Estrogen receptor (ER) beta modulates ERalpha responses to estrogens in the developing rat ventromedial nucleus of the hypothalamus

The mechanisms by which estradiol exerts specific actions on neural function are unclear. In brain the actions of estrogen receptor (ER) alpha are well documented, whereas the functions of ERbeta are not yet fully elucidated. Here, we report that ERbeta inhibits the activity of ERalpha in an anatomi...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2008-09, Vol.149 (9), p.4615
Hauptverfasser:	Gonzales, Keith L, Tetel, Marc J, Wagner, Christine K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Estrogen Receptor alpha - metabolism Estrogen Receptor alpha - physiology Estrogen Receptor beta - metabolism Estrogen Receptor beta - physiology Estrogens - pharmacology Female Nitriles - pharmacology Phenols Preoptic Area - drug effects Preoptic Area - metabolism Protein Binding Pyrazoles - pharmacology Rats Rats, Sprague-Dawley Selective Estrogen Receptor Modulators - pharmacology Tissue Distribution - drug effects Ventromedial Hypothalamic Nucleus - drug effects Ventromedial Hypothalamic Nucleus - growth & development Ventromedial Hypothalamic Nucleus - metabolism
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