Quantitative genetic studies of antisocial behaviour
This paper will broadly review the currently available twin and adoption data on antisocial behaviour (AB). It is argued that quantitative genetic research can make a significant contribution to further the understanding of how AB develops. Genetically informative study designs are particularly usef...
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| Veröffentlicht in: | Philosophical transactions of the Royal Society of London. Series B. Biological sciences 2008-08, Vol.363 (1503), p.2519-2527 |
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| container_title | Philosophical transactions of the Royal Society of London. Series B. Biological sciences |
| container_volume | 363 |
| creator | Viding, Essi Larsson, Henrik Jones, Alice P |
| description | This paper will broadly review the currently available twin and adoption data on antisocial behaviour (AB). It is argued that quantitative genetic research can make a significant contribution to further the understanding of how AB develops. Genetically informative study designs are particularly useful for investigating several important questions such as whether: the heritability estimates vary as a function of assessment method or gender; the relative importance of genetic and environmental influences varies for different types of AB; the environmental risk factors are truly environmental; and genetic vulnerability influences susceptibility to environmental risk. While the current data are not yet directly translatable for prevention and treatment programmes, quantitative genetic research has concrete translational potential. Quantitative genetic research can supplement neuroscience research in informing about different subtypes of AB, such as AB coupled with callous-unemotional traits. Quantitative genetic research is also important in advancing the understanding of the mechanisms by which environmental risk operates. |
| doi_str_mv | 10.1098/rstb.2008.0037 |
| format | Article |
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Series B. Biological sciences</title><addtitle>Philos Trans R Soc Lond B Biol Sci</addtitle><description>This paper will broadly review the currently available twin and adoption data on antisocial behaviour (AB). It is argued that quantitative genetic research can make a significant contribution to further the understanding of how AB develops. Genetically informative study designs are particularly useful for investigating several important questions such as whether: the heritability estimates vary as a function of assessment method or gender; the relative importance of genetic and environmental influences varies for different types of AB; the environmental risk factors are truly environmental; and genetic vulnerability influences susceptibility to environmental risk. While the current data are not yet directly translatable for prevention and treatment programmes, quantitative genetic research has concrete translational potential. Quantitative genetic research can supplement neuroscience research in informing about different subtypes of AB, such as AB coupled with callous-unemotional traits. Quantitative genetic research is also important in advancing the understanding of the mechanisms by which environmental risk operates.</description><subject>Antisocial behavior</subject><subject>Antisocial Behaviour</subject><subject>Antisocial Personality Disorder - genetics</subject><subject>Behavioral genetics</subject><subject>Callous-Unemotional</subject><subject>callousunemotional</subject><subject>Children</subject><subject>Environmental Risk</subject><subject>Genetic</subject><subject>Genetic Research</subject><subject>Heritability</subject><subject>Humans</subject><subject>Medical genetics</subject><subject>Parenting</subject><subject>Quantitative genetics</subject><subject>Review</subject><subject>Social Behavior Disorders - genetics</subject><subject>Social Environment</subject><subject>Twin studies</subject><subject>Twins</subject><issn>0962-8436</issn><issn>1471-2970</issn><issn>1471-2970</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>D8T</sourceid><recordid>eNp9kktvEzEUhUcIREthyw6UFSsS_PZ4g_oIBKRKqFC6vXJmPImTyTjYnpTw6_F0opQItYuRH_c7vvfoTJa9xmiEkco_-BCnI4JQPkKIyifZMWYSD4mS6Gl2jJQgw5xRcZS9CGGBEFJcsufZEU6XjOT4OGNXrW6ijTrajRnMTGOiLQYhtqU1YeCqQVcNrrC6HkzNXG-sa_3L7Fml62Be7daT7OfnT9cXX4aX3yZfL84uh4VQIg4NF3lOldGE6YoorjArRaWkUpRxJilXSCOKDatKknasNFOpCFEs16XABaYn2bB_N9yadTuFtbcr7bfgtIXd1TLtDHCRXLPEv3-QH9ubM3B-lr4WOGNCJvxjjyd2ZcrCNNHr-kB1WGnsHGZuA0QgIXH3wLvdA979ak2IsLKhMHWtG-PaAEIRmdzQBI56sPAuBG-qfROMoMsRuhyhyxG6HJPg7b-j3eO74BKw7AHvtimCFJCJW1ikcJp0hO8_rs83VFCLOaKAcoqRZJwL-GPXfa9UBBtCa-AOOez__zj0sW4PmnjTqxYhOr_3QBBBuRDkPl4bovm9r2u_hJSO5HCTM5iMBTqfjClcJR73_NzO5rfWGzgYJx3WO2N3lgjHKmlOH9V0ExeuiSnhQyVUbZ3-hbKifwG06w_f</recordid><startdate>20080812</startdate><enddate>20080812</enddate><creator>Viding, Essi</creator><creator>Larsson, Henrik</creator><creator>Jones, Alice P</creator><general>The Royal Society</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>5PM</scope><scope>ADTPV</scope><scope>AOWAS</scope><scope>D91</scope><scope>D8T</scope><scope>ZZAVC</scope></search><sort><creationdate>20080812</creationdate><title>Quantitative genetic studies of antisocial behaviour</title><author>Viding, Essi ; Larsson, Henrik ; Jones, Alice P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c696t-e568839ea24af295914d6f9799345473590a031e4fd20a04deb7922948ad61c13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Antisocial behavior</topic><topic>Antisocial Behaviour</topic><topic>Antisocial Personality Disorder - genetics</topic><topic>Behavioral genetics</topic><topic>Callous-Unemotional</topic><topic>callousunemotional</topic><topic>Children</topic><topic>Environmental Risk</topic><topic>Genetic</topic><topic>Genetic Research</topic><topic>Heritability</topic><topic>Humans</topic><topic>Medical genetics</topic><topic>Parenting</topic><topic>Quantitative genetics</topic><topic>Review</topic><topic>Social Behavior Disorders - genetics</topic><topic>Social Environment</topic><topic>Twin studies</topic><topic>Twins</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Viding, Essi</creatorcontrib><creatorcontrib>Larsson, Henrik</creatorcontrib><creatorcontrib>Jones, Alice P</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>SwePub</collection><collection>SwePub Articles</collection><collection>SWEPUB Örebro universitet</collection><collection>SWEPUB Freely available online</collection><collection>SwePub Articles full text</collection><jtitle>Philosophical transactions of the Royal Society of London. 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Genetically informative study designs are particularly useful for investigating several important questions such as whether: the heritability estimates vary as a function of assessment method or gender; the relative importance of genetic and environmental influences varies for different types of AB; the environmental risk factors are truly environmental; and genetic vulnerability influences susceptibility to environmental risk. While the current data are not yet directly translatable for prevention and treatment programmes, quantitative genetic research has concrete translational potential. Quantitative genetic research can supplement neuroscience research in informing about different subtypes of AB, such as AB coupled with callous-unemotional traits. Quantitative genetic research is also important in advancing the understanding of the mechanisms by which environmental risk operates.</abstract><cop>London</cop><pub>The Royal Society</pub><pmid>18434281</pmid><doi>10.1098/rstb.2008.0037</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Antisocial behavior Antisocial Behaviour Antisocial Personality Disorder - genetics Behavioral genetics Callous-Unemotional callousunemotional Children Environmental Risk Genetic Genetic Research Heritability Humans Medical genetics Parenting Quantitative genetics Review Social Behavior Disorders - genetics Social Environment Twin studies Twins |
| title | Quantitative genetic studies of antisocial behaviour |
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