Performance of a direct-detection active matrix flat panel dosimeter (AMFPD) for IMRT measurements
The dosimetric performance of a direct-detection active matrix flat panel dosimeter (AMFPD) is reported for intensity modulated radiation therapy (IMRT) measurements. The AMFPD consists of a -Si : H photodiodes and thin-film transistors deposited on a glass substrate with no overlying scintillator s...
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creator | Chen, Yu Moran, Jean M. Roberts, Donald A. El-Mohri, Youcef Antonuk, Larry E. Fraass, Benedick A. |
description | The dosimetric performance of a direct-detection active matrix flat panel dosimeter (AMFPD) is reported for intensity modulated radiation therapy (IMRT) measurements. The AMFPD consists of
a
-Si
:
H
photodiodes and thin-film transistors deposited on a glass substrate with no overlying scintillator screen or metal plate. The device is operated at 0.8 frames per second in a continuous acquisition or fluoroscopic mode. The effect of the applied bias voltage across the photodiodes on the response of the AMFPD was evaluated because this parameter affects dark signal, lag contributions, and pixel sensitivity. In addition, the AMPFD response was evaluated as a function of dose, dose rate, and energy, for static fields at 10 cm depth. In continuous acquisition mode, the AMFPD maintained a linear dose response
(
r
2
>
0.99999
)
up to at least 1040 cGy. In order to obtain reliable integrated dose results for IMRT fields, the effects of lag on the radiation signal were minimized by operating the system at the highest frame rate and at an appropriate reverse bias voltage. Segmental MLC and dynamic MLC IMRT fields were measured with the AMFPD, and the results were compared to film, using standard methods for reliable film dosimetry. Both AMFPD and film measurements were independently converted to dose in cGy.
γ
and
χ
values were calculated as indices of agreement. The results from the AMFPD were in excellent agreement with those from film. When
2
%
of
D
max
and 2 mm of distance to agreement were used as the criteria,
98
%
of the region of interest (defined as the region where dose is greater than
5
%
of
D
max
) satisfied
|
χ
|
≤
1
on average across the cases that were tested. |
doi_str_mv | 10.1118/1.2805993 |
format | Article |
fullrecord | <record><control><sourceid>wiley_pubme</sourceid><recordid>TN_cdi_pubmed_primary_18196816</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>MP5993</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5093-d6745c6bbd7bdfd53412071ab054bb19d2321d5c4fccb73c1fc0898828e75e183</originalsourceid><addsrcrecordid>eNp9kV1LHDEUhoO06Gp74R8ogd5UYWxOMplJbgTxq4JLF9HrkE-csjNZktHqvzfLLFSQ7dV78-Q5Oe9B6BDICQCIn3BCBeFSsh00o3XLqpoS-QnNCJF1RWvC99B-zn8IIQ3jZBftgQDZCGhmyCx8CjH1erAex4A1dl3ydqycH0t0ccC6xLPHvR5T94LDUo94pQe_xC7mri9Ywj_O5leLiyNcTPhmfnePe6_zU_K9H8b8BX0Oepn9100eoIery_vzX9Xt7-ub87PbynIiWeWatua2Mca1xgXHWQ2UtKAN4bUxIB1lFBy3dbDWtMxCsERIIajwLfcg2AH6PnljHjuVbVcWeLRxGMoeigJhVEhWqKOJsinmnHxQq9T1Or0qIGrdpgK1abOw3yZ29WR67_6Rm_oKUE3A327pX7eb1HyxEZ5O_Pp3et3u9jfvDqNiUFqVwxTB8TbBc0zvBq5c-B_8cdc36TStfg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>Performance of a direct-detection active matrix flat panel dosimeter (AMFPD) for IMRT measurements</title><source>MEDLINE</source><source>Access via Wiley Online Library</source><creator>Chen, Yu ; Moran, Jean M. ; Roberts, Donald A. ; El-Mohri, Youcef ; Antonuk, Larry E. ; Fraass, Benedick A.</creator><creatorcontrib>Chen, Yu ; Moran, Jean M. ; Roberts, Donald A. ; El-Mohri, Youcef ; Antonuk, Larry E. ; Fraass, Benedick A.</creatorcontrib><description>The dosimetric performance of a direct-detection active matrix flat panel dosimeter (AMFPD) is reported for intensity modulated radiation therapy (IMRT) measurements. The AMFPD consists of
a
-Si
:
H
photodiodes and thin-film transistors deposited on a glass substrate with no overlying scintillator screen or metal plate. The device is operated at 0.8 frames per second in a continuous acquisition or fluoroscopic mode. The effect of the applied bias voltage across the photodiodes on the response of the AMFPD was evaluated because this parameter affects dark signal, lag contributions, and pixel sensitivity. In addition, the AMPFD response was evaluated as a function of dose, dose rate, and energy, for static fields at 10 cm depth. In continuous acquisition mode, the AMFPD maintained a linear dose response
(
r
2
>
0.99999
)
up to at least 1040 cGy. In order to obtain reliable integrated dose results for IMRT fields, the effects of lag on the radiation signal were minimized by operating the system at the highest frame rate and at an appropriate reverse bias voltage. Segmental MLC and dynamic MLC IMRT fields were measured with the AMFPD, and the results were compared to film, using standard methods for reliable film dosimetry. Both AMFPD and film measurements were independently converted to dose in cGy.
γ
and
χ
values were calculated as indices of agreement. The results from the AMFPD were in excellent agreement with those from film. When
2
%
of
D
max
and 2 mm of distance to agreement were used as the criteria,
98
%
of the region of interest (defined as the region where dose is greater than
5
%
of
D
max
) satisfied
|
χ
|
≤
1
on average across the cases that were tested.</description><identifier>ISSN: 0094-2405</identifier><identifier>EISSN: 2473-4209</identifier><identifier>DOI: 10.1118/1.2805993</identifier><identifier>PMID: 18196816</identifier><identifier>CODEN: MPHYA6</identifier><language>eng</language><publisher>United States: American Association of Physicists in Medicine</publisher><subject>amorphous silicon ; Ancillary equipment ; Charged currents ; Dark currents ; Dose-Response Relationship, Radiation ; DOSEMETERS ; dosimeters ; dosimetry ; Electric fields ; ELECTRIC POTENTIAL ; FILM DOSIMETRY ; flat panel dosimeter ; Fluoroscopy ; Glass ; Head - diagnostic imaging ; Humans ; Image sensors ; IMRT ; Intensity modulated radiation therapy ; Linear Models ; Male ; Mammography ; Medical imaging ; Neck - diagnostic imaging ; PHOTODIODES ; Prostate - diagnostic imaging ; QUALITY ASSURANCE ; Quality assurance in radiotherapy ; RADIATION DOSES ; radiation therapy ; Radiography ; RADIOLOGY AND NUCLEAR MEDICINE ; Radiometry - instrumentation ; RADIOTHERAPY ; Radiotherapy, Intensity-Modulated - methods ; SI SEMICONDUCTOR DETECTORS ; SILICON ; silicon radiation detectors ; thin film transistors ; THIN FILMS ; TRANSISTORS ; Transistors, Electronic ; Treatment strategy ; Wedges and compensators ; X-Ray Film</subject><ispartof>Medical physics (Lancaster), 2007-12, Vol.34 (12), p.4911-4922</ispartof><rights>American Association of Physicists in Medicine</rights><rights>2007 American Association of Physicists in Medicine</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5093-d6745c6bbd7bdfd53412071ab054bb19d2321d5c4fccb73c1fc0898828e75e183</citedby><cites>FETCH-LOGICAL-c5093-d6745c6bbd7bdfd53412071ab054bb19d2321d5c4fccb73c1fc0898828e75e183</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1118%2F1.2805993$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1118%2F1.2805993$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>230,315,781,785,886,1418,27928,27929,45578,45579</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18196816$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/21032893$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Chen, Yu</creatorcontrib><creatorcontrib>Moran, Jean M.</creatorcontrib><creatorcontrib>Roberts, Donald A.</creatorcontrib><creatorcontrib>El-Mohri, Youcef</creatorcontrib><creatorcontrib>Antonuk, Larry E.</creatorcontrib><creatorcontrib>Fraass, Benedick A.</creatorcontrib><title>Performance of a direct-detection active matrix flat panel dosimeter (AMFPD) for IMRT measurements</title><title>Medical physics (Lancaster)</title><addtitle>Med Phys</addtitle><description>The dosimetric performance of a direct-detection active matrix flat panel dosimeter (AMFPD) is reported for intensity modulated radiation therapy (IMRT) measurements. The AMFPD consists of
a
-Si
:
H
photodiodes and thin-film transistors deposited on a glass substrate with no overlying scintillator screen or metal plate. The device is operated at 0.8 frames per second in a continuous acquisition or fluoroscopic mode. The effect of the applied bias voltage across the photodiodes on the response of the AMFPD was evaluated because this parameter affects dark signal, lag contributions, and pixel sensitivity. In addition, the AMPFD response was evaluated as a function of dose, dose rate, and energy, for static fields at 10 cm depth. In continuous acquisition mode, the AMFPD maintained a linear dose response
(
r
2
>
0.99999
)
up to at least 1040 cGy. In order to obtain reliable integrated dose results for IMRT fields, the effects of lag on the radiation signal were minimized by operating the system at the highest frame rate and at an appropriate reverse bias voltage. Segmental MLC and dynamic MLC IMRT fields were measured with the AMFPD, and the results were compared to film, using standard methods for reliable film dosimetry. Both AMFPD and film measurements were independently converted to dose in cGy.
γ
and
χ
values were calculated as indices of agreement. The results from the AMFPD were in excellent agreement with those from film. When
2
%
of
D
max
and 2 mm of distance to agreement were used as the criteria,
98
%
of the region of interest (defined as the region where dose is greater than
5
%
of
D
max
) satisfied
|
χ
|
≤
1
on average across the cases that were tested.</description><subject>amorphous silicon</subject><subject>Ancillary equipment</subject><subject>Charged currents</subject><subject>Dark currents</subject><subject>Dose-Response Relationship, Radiation</subject><subject>DOSEMETERS</subject><subject>dosimeters</subject><subject>dosimetry</subject><subject>Electric fields</subject><subject>ELECTRIC POTENTIAL</subject><subject>FILM DOSIMETRY</subject><subject>flat panel dosimeter</subject><subject>Fluoroscopy</subject><subject>Glass</subject><subject>Head - diagnostic imaging</subject><subject>Humans</subject><subject>Image sensors</subject><subject>IMRT</subject><subject>Intensity modulated radiation therapy</subject><subject>Linear Models</subject><subject>Male</subject><subject>Mammography</subject><subject>Medical imaging</subject><subject>Neck - diagnostic imaging</subject><subject>PHOTODIODES</subject><subject>Prostate - diagnostic imaging</subject><subject>QUALITY ASSURANCE</subject><subject>Quality assurance in radiotherapy</subject><subject>RADIATION DOSES</subject><subject>radiation therapy</subject><subject>Radiography</subject><subject>RADIOLOGY AND NUCLEAR MEDICINE</subject><subject>Radiometry - instrumentation</subject><subject>RADIOTHERAPY</subject><subject>Radiotherapy, Intensity-Modulated - methods</subject><subject>SI SEMICONDUCTOR DETECTORS</subject><subject>SILICON</subject><subject>silicon radiation detectors</subject><subject>thin film transistors</subject><subject>THIN FILMS</subject><subject>TRANSISTORS</subject><subject>Transistors, Electronic</subject><subject>Treatment strategy</subject><subject>Wedges and compensators</subject><subject>X-Ray Film</subject><issn>0094-2405</issn><issn>2473-4209</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kV1LHDEUhoO06Gp74R8ogd5UYWxOMplJbgTxq4JLF9HrkE-csjNZktHqvzfLLFSQ7dV78-Q5Oe9B6BDICQCIn3BCBeFSsh00o3XLqpoS-QnNCJF1RWvC99B-zn8IIQ3jZBftgQDZCGhmyCx8CjH1erAex4A1dl3ydqycH0t0ccC6xLPHvR5T94LDUo94pQe_xC7mri9Ywj_O5leLiyNcTPhmfnePe6_zU_K9H8b8BX0Oepn9100eoIery_vzX9Xt7-ub87PbynIiWeWatua2Mca1xgXHWQ2UtKAN4bUxIB1lFBy3dbDWtMxCsERIIajwLfcg2AH6PnljHjuVbVcWeLRxGMoeigJhVEhWqKOJsinmnHxQq9T1Or0qIGrdpgK1abOw3yZ29WR67_6Rm_oKUE3A327pX7eb1HyxEZ5O_Pp3et3u9jfvDqNiUFqVwxTB8TbBc0zvBq5c-B_8cdc36TStfg</recordid><startdate>200712</startdate><enddate>200712</enddate><creator>Chen, Yu</creator><creator>Moran, Jean M.</creator><creator>Roberts, Donald A.</creator><creator>El-Mohri, Youcef</creator><creator>Antonuk, Larry E.</creator><creator>Fraass, Benedick A.</creator><general>American Association of Physicists in Medicine</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>OTOTI</scope></search><sort><creationdate>200712</creationdate><title>Performance of a direct-detection active matrix flat panel dosimeter (AMFPD) for IMRT measurements</title><author>Chen, Yu ; Moran, Jean M. ; Roberts, Donald A. ; El-Mohri, Youcef ; Antonuk, Larry E. ; Fraass, Benedick A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5093-d6745c6bbd7bdfd53412071ab054bb19d2321d5c4fccb73c1fc0898828e75e183</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>amorphous silicon</topic><topic>Ancillary equipment</topic><topic>Charged currents</topic><topic>Dark currents</topic><topic>Dose-Response Relationship, Radiation</topic><topic>DOSEMETERS</topic><topic>dosimeters</topic><topic>dosimetry</topic><topic>Electric fields</topic><topic>ELECTRIC POTENTIAL</topic><topic>FILM DOSIMETRY</topic><topic>flat panel dosimeter</topic><topic>Fluoroscopy</topic><topic>Glass</topic><topic>Head - diagnostic imaging</topic><topic>Humans</topic><topic>Image sensors</topic><topic>IMRT</topic><topic>Intensity modulated radiation therapy</topic><topic>Linear Models</topic><topic>Male</topic><topic>Mammography</topic><topic>Medical imaging</topic><topic>Neck - diagnostic imaging</topic><topic>PHOTODIODES</topic><topic>Prostate - diagnostic imaging</topic><topic>QUALITY ASSURANCE</topic><topic>Quality assurance in radiotherapy</topic><topic>RADIATION DOSES</topic><topic>radiation therapy</topic><topic>Radiography</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>Radiometry - instrumentation</topic><topic>RADIOTHERAPY</topic><topic>Radiotherapy, Intensity-Modulated - methods</topic><topic>SI SEMICONDUCTOR DETECTORS</topic><topic>SILICON</topic><topic>silicon radiation detectors</topic><topic>thin film transistors</topic><topic>THIN FILMS</topic><topic>TRANSISTORS</topic><topic>Transistors, Electronic</topic><topic>Treatment strategy</topic><topic>Wedges and compensators</topic><topic>X-Ray Film</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chen, Yu</creatorcontrib><creatorcontrib>Moran, Jean M.</creatorcontrib><creatorcontrib>Roberts, Donald A.</creatorcontrib><creatorcontrib>El-Mohri, Youcef</creatorcontrib><creatorcontrib>Antonuk, Larry E.</creatorcontrib><creatorcontrib>Fraass, Benedick A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>OSTI.GOV</collection><jtitle>Medical physics (Lancaster)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chen, Yu</au><au>Moran, Jean M.</au><au>Roberts, Donald A.</au><au>El-Mohri, Youcef</au><au>Antonuk, Larry E.</au><au>Fraass, Benedick A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Performance of a direct-detection active matrix flat panel dosimeter (AMFPD) for IMRT measurements</atitle><jtitle>Medical physics (Lancaster)</jtitle><addtitle>Med Phys</addtitle><date>2007-12</date><risdate>2007</risdate><volume>34</volume><issue>12</issue><spage>4911</spage><epage>4922</epage><pages>4911-4922</pages><issn>0094-2405</issn><eissn>2473-4209</eissn><coden>MPHYA6</coden><abstract>The dosimetric performance of a direct-detection active matrix flat panel dosimeter (AMFPD) is reported for intensity modulated radiation therapy (IMRT) measurements. The AMFPD consists of
a
-Si
:
H
photodiodes and thin-film transistors deposited on a glass substrate with no overlying scintillator screen or metal plate. The device is operated at 0.8 frames per second in a continuous acquisition or fluoroscopic mode. The effect of the applied bias voltage across the photodiodes on the response of the AMFPD was evaluated because this parameter affects dark signal, lag contributions, and pixel sensitivity. In addition, the AMPFD response was evaluated as a function of dose, dose rate, and energy, for static fields at 10 cm depth. In continuous acquisition mode, the AMFPD maintained a linear dose response
(
r
2
>
0.99999
)
up to at least 1040 cGy. In order to obtain reliable integrated dose results for IMRT fields, the effects of lag on the radiation signal were minimized by operating the system at the highest frame rate and at an appropriate reverse bias voltage. Segmental MLC and dynamic MLC IMRT fields were measured with the AMFPD, and the results were compared to film, using standard methods for reliable film dosimetry. Both AMFPD and film measurements were independently converted to dose in cGy.
γ
and
χ
values were calculated as indices of agreement. The results from the AMFPD were in excellent agreement with those from film. When
2
%
of
D
max
and 2 mm of distance to agreement were used as the criteria,
98
%
of the region of interest (defined as the region where dose is greater than
5
%
of
D
max
) satisfied
|
χ
|
≤
1
on average across the cases that were tested.</abstract><cop>United States</cop><pub>American Association of Physicists in Medicine</pub><pmid>18196816</pmid><doi>10.1118/1.2805993</doi><tpages>12</tpages><oa>free_for_read</oa></addata></record> |
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issn | 0094-2405 2473-4209 |
language | eng |
recordid | cdi_pubmed_primary_18196816 |
source | MEDLINE; Access via Wiley Online Library |
subjects | amorphous silicon Ancillary equipment Charged currents Dark currents Dose-Response Relationship, Radiation DOSEMETERS dosimeters dosimetry Electric fields ELECTRIC POTENTIAL FILM DOSIMETRY flat panel dosimeter Fluoroscopy Glass Head - diagnostic imaging Humans Image sensors IMRT Intensity modulated radiation therapy Linear Models Male Mammography Medical imaging Neck - diagnostic imaging PHOTODIODES Prostate - diagnostic imaging QUALITY ASSURANCE Quality assurance in radiotherapy RADIATION DOSES radiation therapy Radiography RADIOLOGY AND NUCLEAR MEDICINE Radiometry - instrumentation RADIOTHERAPY Radiotherapy, Intensity-Modulated - methods SI SEMICONDUCTOR DETECTORS SILICON silicon radiation detectors thin film transistors THIN FILMS TRANSISTORS Transistors, Electronic Treatment strategy Wedges and compensators X-Ray Film |
title | Performance of a direct-detection active matrix flat panel dosimeter (AMFPD) for IMRT measurements |
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