Performance of a direct-detection active matrix flat panel dosimeter (AMFPD) for IMRT measurements

The dosimetric performance of a direct-detection active matrix flat panel dosimeter (AMFPD) is reported for intensity modulated radiation therapy (IMRT) measurements. The AMFPD consists of a -Si : H photodiodes and thin-film transistors deposited on a glass substrate with no overlying scintillator s...

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Veröffentlicht in:Medical physics (Lancaster) 2007-12, Vol.34 (12), p.4911-4922
Hauptverfasser: Chen, Yu, Moran, Jean M., Roberts, Donald A., El-Mohri, Youcef, Antonuk, Larry E., Fraass, Benedick A.
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container_end_page 4922
container_issue 12
container_start_page 4911
container_title Medical physics (Lancaster)
container_volume 34
creator Chen, Yu
Moran, Jean M.
Roberts, Donald A.
El-Mohri, Youcef
Antonuk, Larry E.
Fraass, Benedick A.
description The dosimetric performance of a direct-detection active matrix flat panel dosimeter (AMFPD) is reported for intensity modulated radiation therapy (IMRT) measurements. The AMFPD consists of a -Si : H photodiodes and thin-film transistors deposited on a glass substrate with no overlying scintillator screen or metal plate. The device is operated at 0.8 frames per second in a continuous acquisition or fluoroscopic mode. The effect of the applied bias voltage across the photodiodes on the response of the AMFPD was evaluated because this parameter affects dark signal, lag contributions, and pixel sensitivity. In addition, the AMPFD response was evaluated as a function of dose, dose rate, and energy, for static fields at 10 cm depth. In continuous acquisition mode, the AMFPD maintained a linear dose response ( r 2 > 0.99999 ) up to at least 1040 cGy. In order to obtain reliable integrated dose results for IMRT fields, the effects of lag on the radiation signal were minimized by operating the system at the highest frame rate and at an appropriate reverse bias voltage. Segmental MLC and dynamic MLC IMRT fields were measured with the AMFPD, and the results were compared to film, using standard methods for reliable film dosimetry. Both AMFPD and film measurements were independently converted to dose in cGy. γ and χ values were calculated as indices of agreement. The results from the AMFPD were in excellent agreement with those from film. When 2 % of D max and 2 mm of distance to agreement were used as the criteria, 98 % of the region of interest (defined as the region where dose is greater than 5 % of D max ) satisfied | χ | ≤ 1 on average across the cases that were tested.
doi_str_mv 10.1118/1.2805993
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Segmental MLC and dynamic MLC IMRT fields were measured with the AMFPD, and the results were compared to film, using standard methods for reliable film dosimetry. Both AMFPD and film measurements were independently converted to dose in cGy. γ and χ values were calculated as indices of agreement. The results from the AMFPD were in excellent agreement with those from film. When 2 % of D max and 2 mm of distance to agreement were used as the criteria, 98 % of the region of interest (defined as the region where dose is greater than 5 % of D max ) satisfied | χ | ≤ 1 on average across the cases that were tested.</description><subject>amorphous silicon</subject><subject>Ancillary equipment</subject><subject>Charged currents</subject><subject>Dark currents</subject><subject>Dose-Response Relationship, Radiation</subject><subject>DOSEMETERS</subject><subject>dosimeters</subject><subject>dosimetry</subject><subject>Electric fields</subject><subject>ELECTRIC POTENTIAL</subject><subject>FILM DOSIMETRY</subject><subject>flat panel dosimeter</subject><subject>Fluoroscopy</subject><subject>Glass</subject><subject>Head - diagnostic imaging</subject><subject>Humans</subject><subject>Image sensors</subject><subject>IMRT</subject><subject>Intensity modulated radiation therapy</subject><subject>Linear Models</subject><subject>Male</subject><subject>Mammography</subject><subject>Medical imaging</subject><subject>Neck - diagnostic imaging</subject><subject>PHOTODIODES</subject><subject>Prostate - diagnostic imaging</subject><subject>QUALITY ASSURANCE</subject><subject>Quality assurance in radiotherapy</subject><subject>RADIATION DOSES</subject><subject>radiation therapy</subject><subject>Radiography</subject><subject>RADIOLOGY AND NUCLEAR MEDICINE</subject><subject>Radiometry - instrumentation</subject><subject>RADIOTHERAPY</subject><subject>Radiotherapy, Intensity-Modulated - methods</subject><subject>SI SEMICONDUCTOR DETECTORS</subject><subject>SILICON</subject><subject>silicon radiation detectors</subject><subject>thin film transistors</subject><subject>THIN FILMS</subject><subject>TRANSISTORS</subject><subject>Transistors, Electronic</subject><subject>Treatment strategy</subject><subject>Wedges and compensators</subject><subject>X-Ray Film</subject><issn>0094-2405</issn><issn>2473-4209</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kV1LHDEUhoO06Gp74R8ogd5UYWxOMplJbgTxq4JLF9HrkE-csjNZktHqvzfLLFSQ7dV78-Q5Oe9B6BDICQCIn3BCBeFSsh00o3XLqpoS-QnNCJF1RWvC99B-zn8IIQ3jZBftgQDZCGhmyCx8CjH1erAex4A1dl3ydqycH0t0ccC6xLPHvR5T94LDUo94pQe_xC7mri9Ywj_O5leLiyNcTPhmfnePe6_zU_K9H8b8BX0Oepn9100eoIery_vzX9Xt7-ub87PbynIiWeWatua2Mca1xgXHWQ2UtKAN4bUxIB1lFBy3dbDWtMxCsERIIajwLfcg2AH6PnljHjuVbVcWeLRxGMoeigJhVEhWqKOJsinmnHxQq9T1Or0qIGrdpgK1abOw3yZ29WR67_6Rm_oKUE3A327pX7eb1HyxEZ5O_Pp3et3u9jfvDqNiUFqVwxTB8TbBc0zvBq5c-B_8cdc36TStfg</recordid><startdate>200712</startdate><enddate>200712</enddate><creator>Chen, Yu</creator><creator>Moran, Jean M.</creator><creator>Roberts, Donald A.</creator><creator>El-Mohri, Youcef</creator><creator>Antonuk, Larry E.</creator><creator>Fraass, Benedick A.</creator><general>American Association of Physicists in Medicine</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>OTOTI</scope></search><sort><creationdate>200712</creationdate><title>Performance of a direct-detection active matrix flat panel dosimeter (AMFPD) for IMRT measurements</title><author>Chen, Yu ; Moran, Jean M. ; Roberts, Donald A. ; El-Mohri, Youcef ; Antonuk, Larry E. ; Fraass, Benedick A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5093-d6745c6bbd7bdfd53412071ab054bb19d2321d5c4fccb73c1fc0898828e75e183</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>amorphous silicon</topic><topic>Ancillary equipment</topic><topic>Charged currents</topic><topic>Dark currents</topic><topic>Dose-Response Relationship, Radiation</topic><topic>DOSEMETERS</topic><topic>dosimeters</topic><topic>dosimetry</topic><topic>Electric fields</topic><topic>ELECTRIC POTENTIAL</topic><topic>FILM DOSIMETRY</topic><topic>flat panel dosimeter</topic><topic>Fluoroscopy</topic><topic>Glass</topic><topic>Head - diagnostic imaging</topic><topic>Humans</topic><topic>Image sensors</topic><topic>IMRT</topic><topic>Intensity modulated radiation therapy</topic><topic>Linear Models</topic><topic>Male</topic><topic>Mammography</topic><topic>Medical imaging</topic><topic>Neck - diagnostic imaging</topic><topic>PHOTODIODES</topic><topic>Prostate - diagnostic imaging</topic><topic>QUALITY ASSURANCE</topic><topic>Quality assurance in radiotherapy</topic><topic>RADIATION DOSES</topic><topic>radiation therapy</topic><topic>Radiography</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>Radiometry - instrumentation</topic><topic>RADIOTHERAPY</topic><topic>Radiotherapy, Intensity-Modulated - methods</topic><topic>SI SEMICONDUCTOR DETECTORS</topic><topic>SILICON</topic><topic>silicon radiation detectors</topic><topic>thin film transistors</topic><topic>THIN FILMS</topic><topic>TRANSISTORS</topic><topic>Transistors, Electronic</topic><topic>Treatment strategy</topic><topic>Wedges and compensators</topic><topic>X-Ray Film</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chen, Yu</creatorcontrib><creatorcontrib>Moran, Jean M.</creatorcontrib><creatorcontrib>Roberts, Donald A.</creatorcontrib><creatorcontrib>El-Mohri, Youcef</creatorcontrib><creatorcontrib>Antonuk, Larry E.</creatorcontrib><creatorcontrib>Fraass, Benedick A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>OSTI.GOV</collection><jtitle>Medical physics (Lancaster)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chen, Yu</au><au>Moran, Jean M.</au><au>Roberts, Donald A.</au><au>El-Mohri, Youcef</au><au>Antonuk, Larry E.</au><au>Fraass, Benedick A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Performance of a direct-detection active matrix flat panel dosimeter (AMFPD) for IMRT measurements</atitle><jtitle>Medical physics (Lancaster)</jtitle><addtitle>Med Phys</addtitle><date>2007-12</date><risdate>2007</risdate><volume>34</volume><issue>12</issue><spage>4911</spage><epage>4922</epage><pages>4911-4922</pages><issn>0094-2405</issn><eissn>2473-4209</eissn><coden>MPHYA6</coden><abstract>The dosimetric performance of a direct-detection active matrix flat panel dosimeter (AMFPD) is reported for intensity modulated radiation therapy (IMRT) measurements. The AMFPD consists of a -Si : H photodiodes and thin-film transistors deposited on a glass substrate with no overlying scintillator screen or metal plate. The device is operated at 0.8 frames per second in a continuous acquisition or fluoroscopic mode. The effect of the applied bias voltage across the photodiodes on the response of the AMFPD was evaluated because this parameter affects dark signal, lag contributions, and pixel sensitivity. In addition, the AMPFD response was evaluated as a function of dose, dose rate, and energy, for static fields at 10 cm depth. In continuous acquisition mode, the AMFPD maintained a linear dose response ( r 2 &gt; 0.99999 ) up to at least 1040 cGy. In order to obtain reliable integrated dose results for IMRT fields, the effects of lag on the radiation signal were minimized by operating the system at the highest frame rate and at an appropriate reverse bias voltage. Segmental MLC and dynamic MLC IMRT fields were measured with the AMFPD, and the results were compared to film, using standard methods for reliable film dosimetry. Both AMFPD and film measurements were independently converted to dose in cGy. γ and χ values were calculated as indices of agreement. The results from the AMFPD were in excellent agreement with those from film. When 2 % of D max and 2 mm of distance to agreement were used as the criteria, 98 % of the region of interest (defined as the region where dose is greater than 5 % of D max ) satisfied | χ | ≤ 1 on average across the cases that were tested.</abstract><cop>United States</cop><pub>American Association of Physicists in Medicine</pub><pmid>18196816</pmid><doi>10.1118/1.2805993</doi><tpages>12</tpages><oa>free_for_read</oa></addata></record>
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subjects amorphous silicon
Ancillary equipment
Charged currents
Dark currents
Dose-Response Relationship, Radiation
DOSEMETERS
dosimeters
dosimetry
Electric fields
ELECTRIC POTENTIAL
FILM DOSIMETRY
flat panel dosimeter
Fluoroscopy
Glass
Head - diagnostic imaging
Humans
Image sensors
IMRT
Intensity modulated radiation therapy
Linear Models
Male
Mammography
Medical imaging
Neck - diagnostic imaging
PHOTODIODES
Prostate - diagnostic imaging
QUALITY ASSURANCE
Quality assurance in radiotherapy
RADIATION DOSES
radiation therapy
Radiography
RADIOLOGY AND NUCLEAR MEDICINE
Radiometry - instrumentation
RADIOTHERAPY
Radiotherapy, Intensity-Modulated - methods
SI SEMICONDUCTOR DETECTORS
SILICON
silicon radiation detectors
thin film transistors
THIN FILMS
TRANSISTORS
Transistors, Electronic
Treatment strategy
Wedges and compensators
X-Ray Film
title Performance of a direct-detection active matrix flat panel dosimeter (AMFPD) for IMRT measurements
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