Role of Aberrant Glycosylation of IgA1 Molecules in the Pathogenesis of IgA Nephropathy

Studies of the properties of immune complexes (IC) in the circulation, urine, and mesangium of IgA nephropathy (IgAN) patients have provided data relevant to the pathogenesis of this disease. IC contain predominantly polymeric IgA1 molecules which are deficient in galactose (Gal) residues on O-linke...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Kidney & blood pressure research 2008-01, Vol.31 (1), p.29-37
Hauptverfasser:	Mestecky, J., Tomana, M., Moldoveanu, Z., Julian, B.A., Suzuki, H., Matousovic, K., Renfrow, M.B., Novak, L., Wyatt, R.J., Novak, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Glomerulonephritis, IGA - immunology Glomerulonephritis, IGA - metabolism Glomerulonephritis, IGA - pathology Glycosylation Humans Immunoglobulin A - metabolism Immunoglobulin A - physiology Review
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!