LOC387715/HTRA1 and Complement Factor H Variants in Patients with Age-Related Macular Degeneration Seen at the Mayo Clinic

Purpose: To confirm association of the complement factor H allelic variant (CFH Y402H) and the LOC387715/HTRA1 (LOC387715 A69S) risk alleles with age-related macular degeneration (AMD). Study Population: Study of 89 Caucasian patients with neovascular (exudative) AMD and 232 Caucasian controls.Metho...

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Veröffentlicht in:	Ophthalmic genetics 2007-12, Vol.28 (4), p.203-207
Hauptverfasser:	Pulido, Jose S., Peterson, Lisa M., Mutapcic, Lejla, Bryant, Sandra, Highsmith, W. Edward
Format:	Artikel
Sprache:	eng
Schlagworte:	Age-related macular degeneration association study Base Sequence Complement Factor H - genetics complement H DNA Primers Genetic Predisposition to Disease genetics Humans Macular Degeneration - genetics Minnesota Polymerase Chain Reaction Polymorphism, Single Nucleotide
Online-Zugang:	Volltext
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