Molecular Genetics of RB1--The Retinoblastoma Gene

Thirty-seven years ago Alfred Knudson proposed his "two-hit" theory of the molecular etiology of retinoblastoma, establishing an elegant conceptual paradigm for tumorigenesis in general. A great body of work has subsequently elucidated the structure and function of the RB1 gene and the bio...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Seminars in ophthalmology 2007-10, Vol.22 (4), p.247-254
Hauptverfasser:	Leiderman, Yannek I., Kiss, Szilárd, Mukai, Shizuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Genes, Retinoblastoma - physiology Humans Molecular Biology Retinal Neoplasms - genetics retinoblastoma Retinoblastoma - genetics retinoblastoma gene Retinoblastoma Protein - genetics tumor suppressor
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!