Expression of dystroglycan correlates with tumor grade and predicts survival in renal cell carcinoma

The dystroglycan (DG) complex is a transmembrane glycoprotein that forms a continuous link from the extracellular matrix to the actin cytoskeleton. Deregulated expression of DG has been reported in a variety of human malignancies and related to tumor aggressiveness. In this study expression of the α...

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Veröffentlicht in:	Cancer biology & therapy 2007-12, Vol.6 (12), p.1840-1846
Hauptverfasser:	Sgambato, A., Camerini, A., Amoroso, D., Genovese, G., De Luca, F., Cecchi, M., Migaldi, M., Rettino, A., Valsuani, C., Tartarelli, G., Donati, S., Siclari, O., Rossi, G., Cittadini, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma, Clear Cell - genetics Adenocarcinoma, Clear Cell - metabolism Adenocarcinoma, Clear Cell - mortality Adenocarcinoma, Clear Cell - pathology Adult Aged Aged, 80 and over Binding Biology Bioscience Calcium Cancer Carcinoma, Renal Cell - genetics Carcinoma, Renal Cell - metabolism Carcinoma, Renal Cell - mortality Carcinoma, Renal Cell - pathology Cell Cycle Disease-Free Survival Dystroglycans - analysis Dystroglycans - deficiency Dystroglycans - genetics Dystroglycans - physiology Female Gene Expression Regulation, Neoplastic Humans Italy - epidemiology Kaplan-Meier Estimate Kidney Neoplasms - genetics Kidney Neoplasms - metabolism Kidney Neoplasms - mortality Kidney Neoplasms - pathology Landes Male Middle Aged Neoplasm Proteins - analysis Neoplasm Proteins - deficiency Neoplasm Proteins - genetics Neoplasm Proteins - physiology Neoplasm Staging Organogenesis Prognosis Proportional Hazards Models Proteins Recurrence Survival Analysis
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