Acetyl-L-Carnitine Prevents Selenite-Induced Cataractogenesis in an Experimental Animal Model

Purpose: To investigate whether acetyl-L-carnitine (ALCAR) retards selenite-induced cataractogenesis in vivo. Methods: On postpartum day 10, group I pups received intraperitoneal saline and group II and group III pups received subcutaneous sodium selenite; Group III pups also received intraperitonea...

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Veröffentlicht in:	Current eye research 2007-11, Vol.32 (11), p.961-971
Hauptverfasser:	Elanchezhian, R., Ramesh, E., Sakthivel, M., Isai, M., Geraldine, P., Rajamohan, M., Jesudasan, C. Nelson, Thomas, P. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	acetyl-L-carnitine Acetylcarnitine - therapeutic use Animals antioxidant enzymes Antioxidants Catalase - metabolism Cataract - chemically induced Cataract - enzymology Cataract - prevention & control cataractogenesis Disease Models, Animal Electrophoresis, Polyacrylamide Gel Glutathione Peroxidase - metabolism Glutathione Reductase Glutathione Transferase - metabolism Injections, Subcutaneous Lens, Crystalline - drug effects Lens, Crystalline - enzymology Lipid Peroxidation Oxidation-Reduction Oxidative Stress Rats Rats, Wistar selenite cataract Sodium Selenite - toxicity Superoxide Dismutase - metabolism
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