Activation of Peroxisome Proliferator–Activated Receptor (PPAR)δ Promotes Reversal of Multiple Metabolic Abnormalities, Reduces Oxidative Stress, and Increases Fatty Acid Oxidation in Moderately Obese Men

Activation of Peroxisome Proliferator–Activated Receptor (PPAR)δ Promotes Reversal of Multiple Metabolic Abnormalities, Reduces Oxidative Stress, and Increases Fatty Acid Oxidation in Moderately Obese Men Ulf Risérus 1 , Dennis Sprecher 2 , Tony Johnson 2 , Eric Olson 2 , Sandra Hirschberg 2 , Aixue...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2008-02, Vol.57 (2), p.332-339
Hauptverfasser:	RISERUS, Ulf, SPRECHER, Dennis, STRUM, Jay C, BASU, Samar, CHEESEMAN, Jane, FIELDING, Barbara A, HUMPHREYS, Sandy M, DANOFF, Theodore, MOORE, Niall R, MURGATROYD, Peter, O'RAHILLY, Stephen, SUTTON, Pauline, JOHNSON, Tony, WILLSON, Tim, HASSALL, David, FRAYN, Keith N, KARPE, Fredrik, OLSON, Eric, HIRSCHBERG, Sandra, AIXUE LIU, ZEKE FANG, HEGDE, Priti, RICHARDS, Duncan, SAROV-BLAT, Leli
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Apolipoproteins B - blood Apolipoproteins B - drug effects Biological and medical sciences Care and treatment Cholesterol, HDL - blood Cholesterol, HDL - drug effects Diabetes. Impaired glucose tolerance Double-Blind Method Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Fat metabolism Fatty Acids - metabolism Fibric acids Genetic aspects Humans Magnetic Resonance Imaging Male Medical sciences MEDICIN MEDICINE Metabolic diseases Metabolic syndrome X Middle Aged Obesity Obesity - physiopathology Oxidation-Reduction Oxidative stress Oxidative Stress - physiology Peroxisomes Physiological aspects Placebos PPAR delta - agonists PPAR delta - physiology Thiazoles - pharmacology Triglycerides - blood
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