Antioxidant Vitamins and Adrenocorticotrophic Hormone-Induced Hypertension in Rats

This study examined whether the anti-oxidants ascorbic acid, α- or γ-tocopherol, could modify adrenocorticotrophic hormone (ACTH)-hypertension in Sprague-Dawley rats, a model associated with increased oxidative stress. Systolic blood pressure (SBP) was measured by the tail-cuff method. After four da...

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Veröffentlicht in:	Clinical and experimental hypertension (1993) 2007-10, Vol.29 (7), p.465-478
Hauptverfasser:	Schyvens, Christopher G., Andrews, Miles C., Tam, Rachel, Mori, Trevor A., Croft, Kevin D., McKenzie, Katja U.S., Whitworth, Judith A., Zhang, Yi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenocorticotropic Hormone - adverse effects Animals Antioxidants - pharmacology Arterial hypertension. Arterial hypotension ascorbic acid Ascorbic Acid - pharmacology Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Clinical manifestations. Epidemiology. Investigative techniques. Etiology Disease Models, Animal Experimental diseases hypertension Hypertension - chemically induced Hypertension - drug therapy Male Medical sciences Oxidative Stress - drug effects Rats Rats, Sprague-Dawley Systole - drug effects tocopherol Tocopherols - pharmacology Vitamins - pharmacology
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