Primary cilia mediate mechanosensing in bone cells by a calcium-independent mechanism

Primary cilia are sensory organelles that translate extracellular chemical and mechanical cues into cellular responses. Bone is an exquisitely mechanosensitive organ, and its homeostasis depends on the ability of bone cells to sense and respond to mechanical stimuli. One such stimulus is dynamic flu...

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Veröffentlicht in:Proceedings of the National Academy of Sciences - PNAS 2007-08, Vol.104 (33), p.13325-13330
Hauptverfasser: Malone, Amanda M.D, Anderson, Charles T, Tummala, Padmaja, Kwon, Ronald Y, Johnston, Tyler R, Stearns, Tim, Jacobs, Christopher R
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Sprache:eng
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