c-Jun N-Terminal Kinase 1 Is Required for Toll-Like Receptor 1 Gene Expression in Macrophages

The regulation of innate immune responses to pathogens occurs through the interaction of Toll-like receptors (TLRs) with pathogen-associated molecular patterns and the activation of several signaling pathways whose contribution to the overall innate immune response to pathogens is poorly understood....

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Veröffentlicht in:	Infection and Immunity 2007-10, Vol.75 (10), p.5027-5034
Hauptverfasser:	Izadi, Hooman, Motameni, Amirreza T, Bates, Tonya C, Olivera, Elias R, Villar-Suarez, Vega, Joshi, Ila, Garg, Renu, Osborne, Barbara A, Davis, Roger J, Rincón, Mercedes, Anguita, Juan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacteriology Base Sequence Binding Sites - genetics Biological and medical sciences Borrelia burgdorferi Borrelia burgdorferi - immunology Cell Line Cells, Cultured Fundamental and applied biological sciences. Psychology Gene Expression Regulation Host Response and Inflammation Humans Macrophages - immunology Mice Mice, Inbred C57BL Microbiology Mitogen-Activated Protein Kinase 8 - physiology Molecular Sequence Data Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains Promoter Regions, Genetic Toll-Like Receptor 1 - genetics
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