Gliotoxin Is a Virulence Factor of Aspergillus fumigatus: gliP Deletion Attenuates Virulence in Mice Immunosuppressed with Hydrocortisone
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Veröffentlicht in: | Eukaryotic Cell 2007-09, Vol.6 (9), p.1562-1569 |
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creator | Sugui, Janyce A Pardo, Julian Chang, Yun C Zarember, Kol A Nardone, Glenn Galvez, Eva M Müllbacher, Arno Gallin, John I Simon, Markus M Kwon-Chung, Kyung J |
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</description><identifier>ISSN: 1535-9778</identifier><identifier>EISSN: 1535-9786</identifier><identifier>DOI: 10.1128/EC.00141-07</identifier><identifier>PMID: 17601876</identifier><language>eng</language><publisher>United States: American Society for Microbiology</publisher><subject>Animals ; Apoptosis ; Aspergillosis - microbiology ; Aspergillosis - pathology ; Aspergillus fumigatus ; Aspergillus fumigatus - genetics ; Aspergillus fumigatus - pathogenicity ; bcl-2 Homologous Antagonist-Killer Protein - metabolism ; Fungal Proteins - genetics ; Gene Deletion ; Gliotoxin - biosynthesis ; Humans ; Hydrocortisone - pharmacology ; Immunosuppression ; Mice ; Mice, Inbred BALB C ; Neutrophils - metabolism ; Neutrophils - microbiology ; Peptide Synthases - genetics ; Respiratory Burst ; Superoxides - metabolism ; Virulence - genetics ; Virulence Factors - biosynthesis ; Virulence Factors - genetics</subject><ispartof>Eukaryotic Cell, 2007-09, Vol.6 (9), p.1562-1569</ispartof><rights>Copyright © 2007, American Society for Microbiology 2007</rights><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c481t-7a7506469f0060ad0a27faeb29079ef222a63a3a4397904a0e5dcdcb7e810aa13</citedby><cites>FETCH-LOGICAL-c481t-7a7506469f0060ad0a27faeb29079ef222a63a3a4397904a0e5dcdcb7e810aa13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2043361/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC2043361/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,3179,3180,27915,27916,53782,53784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17601876$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sugui, Janyce A</creatorcontrib><creatorcontrib>Pardo, Julian</creatorcontrib><creatorcontrib>Chang, Yun C</creatorcontrib><creatorcontrib>Zarember, Kol A</creatorcontrib><creatorcontrib>Nardone, Glenn</creatorcontrib><creatorcontrib>Galvez, Eva M</creatorcontrib><creatorcontrib>Müllbacher, Arno</creatorcontrib><creatorcontrib>Gallin, John I</creatorcontrib><creatorcontrib>Simon, Markus M</creatorcontrib><creatorcontrib>Kwon-Chung, Kyung J</creatorcontrib><title>Gliotoxin Is a Virulence Factor of Aspergillus fumigatus: gliP Deletion Attenuates Virulence in Mice Immunosuppressed with Hydrocortisone</title><title>Eukaryotic Cell</title><addtitle>Eukaryot Cell</addtitle><description>Classifications
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</description><subject>Animals</subject><subject>Apoptosis</subject><subject>Aspergillosis - microbiology</subject><subject>Aspergillosis - pathology</subject><subject>Aspergillus fumigatus</subject><subject>Aspergillus fumigatus - genetics</subject><subject>Aspergillus fumigatus - pathogenicity</subject><subject>bcl-2 Homologous Antagonist-Killer Protein - metabolism</subject><subject>Fungal Proteins - genetics</subject><subject>Gene Deletion</subject><subject>Gliotoxin - biosynthesis</subject><subject>Humans</subject><subject>Hydrocortisone - pharmacology</subject><subject>Immunosuppression</subject><subject>Mice</subject><subject>Mice, Inbred BALB C</subject><subject>Neutrophils - metabolism</subject><subject>Neutrophils - microbiology</subject><subject>Peptide Synthases - genetics</subject><subject>Respiratory Burst</subject><subject>Superoxides - metabolism</subject><subject>Virulence - genetics</subject><subject>Virulence Factors - biosynthesis</subject><subject>Virulence Factors - genetics</subject><issn>1535-9778</issn><issn>1535-9786</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc1u1DAUhS0EomVgxR55gdigFP8kdsICaTRM25GKYAFsrTvJTcaQxKl_KH0E3poMMyplxeaeK_nTZ1uHkOecnXEuyjfr1RljPOcZ0w_IKS9kkVW6VA_vdl2ekCchfJupotLyMTnhWjFeanVKfl301kX30450EyjQr9anHsca6TnU0XnqWroME_rO9n0KtE2D7SCm8JZ2vf1E32OP0bqRLmPEMUHEcM8xWz_YOTfDkEYX0jR5DAEbemPjjl7eNt7Vzkcb3IhPyaMW-oDPjrkgX87Xn1eX2dXHi81qeZXVecljpkEXTOWqahlTDBoGQreAW1ExXWErhAAlQUIuK12xHBgWTd3UW40lZwBcLsi7g3dK2wGbGsfooTeTtwP4W-PAmn9PRrsznfthBMulVHvBq6PAu-uEIZrBhhr7HkZ0KRhViqJUPP8vKJjkupzngrw-gLV3IXhs717Dmdl3bNYr86djw_RMv7j_gb_ssdQZeHkAdrbb3ViPBsJgMH3f322UqQwvlJC_AfmYsds</recordid><startdate>20070901</startdate><enddate>20070901</enddate><creator>Sugui, Janyce A</creator><creator>Pardo, Julian</creator><creator>Chang, Yun C</creator><creator>Zarember, Kol A</creator><creator>Nardone, Glenn</creator><creator>Galvez, Eva M</creator><creator>Müllbacher, Arno</creator><creator>Gallin, John I</creator><creator>Simon, Markus M</creator><creator>Kwon-Chung, Kyung J</creator><general>American Society for Microbiology</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7T7</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>M7N</scope><scope>P64</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20070901</creationdate><title>Gliotoxin Is a Virulence Factor of Aspergillus fumigatus: gliP Deletion Attenuates Virulence in Mice Immunosuppressed with Hydrocortisone</title><author>Sugui, Janyce A ; 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</abstract><cop>United States</cop><pub>American Society for Microbiology</pub><pmid>17601876</pmid><doi>10.1128/EC.00141-07</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
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source | American Society for Microbiology; MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
subjects | Animals Apoptosis Aspergillosis - microbiology Aspergillosis - pathology Aspergillus fumigatus Aspergillus fumigatus - genetics Aspergillus fumigatus - pathogenicity bcl-2 Homologous Antagonist-Killer Protein - metabolism Fungal Proteins - genetics Gene Deletion Gliotoxin - biosynthesis Humans Hydrocortisone - pharmacology Immunosuppression Mice Mice, Inbred BALB C Neutrophils - metabolism Neutrophils - microbiology Peptide Synthases - genetics Respiratory Burst Superoxides - metabolism Virulence - genetics Virulence Factors - biosynthesis Virulence Factors - genetics |
title | Gliotoxin Is a Virulence Factor of Aspergillus fumigatus: gliP Deletion Attenuates Virulence in Mice Immunosuppressed with Hydrocortisone |
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