Bleeding complication due to accumulation of low-molecular-weight heparin in a patient with renal insufficiency
We report of a 71-year-old woman with a history of chronic analgesic nephropathy, who underwent coronary angiography. Because of anterior ventricular aneurysm, anticoagulation with nadroparine was installed. Continued ACE-inhibitor and ASA with additional intravenous contrast substance lead to acute...
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| Veröffentlicht in: | Praxis (Bern. 1994) 2007-05, Vol.96 (18), p.733 |
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| creator | Schneiter, S Huynh-Do, U Heizmann, M |
| description | We report of a 71-year-old woman with a history of chronic analgesic nephropathy, who underwent coronary angiography. Because of anterior ventricular aneurysm, anticoagulation with nadroparine was installed. Continued ACE-inhibitor and ASA with additional intravenous contrast substance lead to acute tubular necrosis with rapid decline of the renal function. Due to accumulation of the low molecular weight heparin, the patient developed an extensive retroperitoneal haematoma with circulatory shock and temporary anuric kidney failure. Low molecular weight heparins are commonly used during percutaneous coronary interventions. They are as safe and efficient compared to unfractioned heparin. But due to their renal elimination, they have to be monitored by measuring anti-factor Xa-activity if creatinine-clearance is |
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Because of anterior ventricular aneurysm, anticoagulation with nadroparine was installed. Continued ACE-inhibitor and ASA with additional intravenous contrast substance lead to acute tubular necrosis with rapid decline of the renal function. Due to accumulation of the low molecular weight heparin, the patient developed an extensive retroperitoneal haematoma with circulatory shock and temporary anuric kidney failure. Low molecular weight heparins are commonly used during percutaneous coronary interventions. They are as safe and efficient compared to unfractioned heparin. But due to their renal elimination, they have to be monitored by measuring anti-factor Xa-activity if creatinine-clearance is <30 ml/min.</description><identifier>ISSN: 1661-8157</identifier><identifier>PMID: 17520842</identifier><language>ger</language><publisher>Switzerland</publisher><subject>Acute Kidney Injury - blood ; Acute Kidney Injury - chemically induced ; Acute Kidney Injury - therapy ; Acute Kidney Injury - urine ; Adolescent ; Age Factors ; Aged ; Anticoagulants - administration & dosage ; Anticoagulants - adverse effects ; Anuria - chemically induced ; Child ; Creatinine - blood ; Creatinine - urine ; Enoxaparin - administration & dosage ; Enoxaparin - adverse effects ; Enoxaparin - therapeutic use ; Factor Xa Inhibitors ; Female ; Glomerular Filtration Rate ; Hematoma - chemically induced ; Hematoma - drug therapy ; Humans ; Meta-Analysis as Topic ; Monitoring, Physiologic ; Nadroparin - administration & dosage ; Nadroparin - adverse effects ; Randomized Controlled Trials as Topic ; Renal Dialysis ; Renal Insufficiency - blood ; Renal Insufficiency - complications ; Renal Insufficiency - urine ; Retroperitoneal Space ; Risk Factors ; Shock - chemically induced ; Time Factors ; Treatment Outcome</subject><ispartof>Praxis (Bern. 1994), 2007-05, Vol.96 (18), p.733</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,782,786</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17520842$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Schneiter, S</creatorcontrib><creatorcontrib>Huynh-Do, U</creatorcontrib><creatorcontrib>Heizmann, M</creatorcontrib><title>Bleeding complication due to accumulation of low-molecular-weight heparin in a patient with renal insufficiency</title><title>Praxis (Bern. 1994)</title><addtitle>Praxis (Bern 1994)</addtitle><description>We report of a 71-year-old woman with a history of chronic analgesic nephropathy, who underwent coronary angiography. Because of anterior ventricular aneurysm, anticoagulation with nadroparine was installed. Continued ACE-inhibitor and ASA with additional intravenous contrast substance lead to acute tubular necrosis with rapid decline of the renal function. Due to accumulation of the low molecular weight heparin, the patient developed an extensive retroperitoneal haematoma with circulatory shock and temporary anuric kidney failure. Low molecular weight heparins are commonly used during percutaneous coronary interventions. They are as safe and efficient compared to unfractioned heparin. But due to their renal elimination, they have to be monitored by measuring anti-factor Xa-activity if creatinine-clearance is <30 ml/min.</description><subject>Acute Kidney Injury - blood</subject><subject>Acute Kidney Injury - chemically induced</subject><subject>Acute Kidney Injury - therapy</subject><subject>Acute Kidney Injury - urine</subject><subject>Adolescent</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Anticoagulants - administration & dosage</subject><subject>Anticoagulants - adverse effects</subject><subject>Anuria - chemically induced</subject><subject>Child</subject><subject>Creatinine - blood</subject><subject>Creatinine - urine</subject><subject>Enoxaparin - administration & dosage</subject><subject>Enoxaparin - adverse effects</subject><subject>Enoxaparin - therapeutic use</subject><subject>Factor Xa Inhibitors</subject><subject>Female</subject><subject>Glomerular Filtration Rate</subject><subject>Hematoma - chemically induced</subject><subject>Hematoma - drug therapy</subject><subject>Humans</subject><subject>Meta-Analysis as Topic</subject><subject>Monitoring, Physiologic</subject><subject>Nadroparin - administration & dosage</subject><subject>Nadroparin - adverse effects</subject><subject>Randomized Controlled Trials as Topic</subject><subject>Renal Dialysis</subject><subject>Renal Insufficiency - blood</subject><subject>Renal Insufficiency - complications</subject><subject>Renal Insufficiency - urine</subject><subject>Retroperitoneal Space</subject><subject>Risk Factors</subject><subject>Shock - chemically induced</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><issn>1661-8157</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1z8tqwzAQBVAtWpo07S8U_YBAkiXZXrahLwhkk32YjEeximwJPwj5-xrSwsCFw-XC3LG1ck6JStlyxR7H8UdKZ2ptH9hKlVbLyug1S2-RqAn9mWPqcgwIU0g9b2biU-KAOHdzvFnyPKaL6FIkXGwQFwrnduItZRhCz5cDnpcu9RO_hKnlA_UQFx9n7wMujtcndu8hjvT8lxt2-Hg_bL_Ebv_5vX3diWyNFkBKOg9Gg5OlptoUUjdofW1NjbqSWEjnPDnfkIdSoau0VLUz2uHJK1UWG_Zym83zqaPmmIfQwXA9_j9e_AINUVV-</recordid><startdate>20070502</startdate><enddate>20070502</enddate><creator>Schneiter, S</creator><creator>Huynh-Do, U</creator><creator>Heizmann, M</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>20070502</creationdate><title>Bleeding complication due to accumulation of low-molecular-weight heparin in a patient with renal insufficiency</title><author>Schneiter, S ; Huynh-Do, U ; Heizmann, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p542-ae106fa42a6072e94302dc5f9549c280c3066fe6fdefa71c6820196426cbf1173</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>ger</language><creationdate>2007</creationdate><topic>Acute Kidney Injury - blood</topic><topic>Acute Kidney Injury - chemically induced</topic><topic>Acute Kidney Injury - therapy</topic><topic>Acute Kidney Injury - urine</topic><topic>Adolescent</topic><topic>Age Factors</topic><topic>Aged</topic><topic>Anticoagulants - administration & dosage</topic><topic>Anticoagulants - adverse effects</topic><topic>Anuria - chemically induced</topic><topic>Child</topic><topic>Creatinine - blood</topic><topic>Creatinine - urine</topic><topic>Enoxaparin - administration & dosage</topic><topic>Enoxaparin - adverse effects</topic><topic>Enoxaparin - therapeutic use</topic><topic>Factor Xa Inhibitors</topic><topic>Female</topic><topic>Glomerular Filtration Rate</topic><topic>Hematoma - chemically induced</topic><topic>Hematoma - drug therapy</topic><topic>Humans</topic><topic>Meta-Analysis as Topic</topic><topic>Monitoring, Physiologic</topic><topic>Nadroparin - administration & dosage</topic><topic>Nadroparin - adverse effects</topic><topic>Randomized Controlled Trials as Topic</topic><topic>Renal Dialysis</topic><topic>Renal Insufficiency - blood</topic><topic>Renal Insufficiency - complications</topic><topic>Renal Insufficiency - urine</topic><topic>Retroperitoneal Space</topic><topic>Risk Factors</topic><topic>Shock - chemically induced</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Schneiter, S</creatorcontrib><creatorcontrib>Huynh-Do, U</creatorcontrib><creatorcontrib>Heizmann, M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Praxis (Bern. 1994)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Schneiter, S</au><au>Huynh-Do, U</au><au>Heizmann, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Bleeding complication due to accumulation of low-molecular-weight heparin in a patient with renal insufficiency</atitle><jtitle>Praxis (Bern. 1994)</jtitle><addtitle>Praxis (Bern 1994)</addtitle><date>2007-05-02</date><risdate>2007</risdate><volume>96</volume><issue>18</issue><spage>733</spage><pages>733-</pages><issn>1661-8157</issn><abstract>We report of a 71-year-old woman with a history of chronic analgesic nephropathy, who underwent coronary angiography. Because of anterior ventricular aneurysm, anticoagulation with nadroparine was installed. Continued ACE-inhibitor and ASA with additional intravenous contrast substance lead to acute tubular necrosis with rapid decline of the renal function. Due to accumulation of the low molecular weight heparin, the patient developed an extensive retroperitoneal haematoma with circulatory shock and temporary anuric kidney failure. Low molecular weight heparins are commonly used during percutaneous coronary interventions. They are as safe and efficient compared to unfractioned heparin. But due to their renal elimination, they have to be monitored by measuring anti-factor Xa-activity if creatinine-clearance is <30 ml/min.</abstract><cop>Switzerland</cop><pmid>17520842</pmid></addata></record> |
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| ispartof | Praxis (Bern. 1994), 2007-05, Vol.96 (18), p.733 |
| issn | 1661-8157 |
| language | ger |
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| source | Hogrefe eContent; MEDLINE |
| subjects | Acute Kidney Injury - blood Acute Kidney Injury - chemically induced Acute Kidney Injury - therapy Acute Kidney Injury - urine Adolescent Age Factors Aged Anticoagulants - administration & dosage Anticoagulants - adverse effects Anuria - chemically induced Child Creatinine - blood Creatinine - urine Enoxaparin - administration & dosage Enoxaparin - adverse effects Enoxaparin - therapeutic use Factor Xa Inhibitors Female Glomerular Filtration Rate Hematoma - chemically induced Hematoma - drug therapy Humans Meta-Analysis as Topic Monitoring, Physiologic Nadroparin - administration & dosage Nadroparin - adverse effects Randomized Controlled Trials as Topic Renal Dialysis Renal Insufficiency - blood Renal Insufficiency - complications Renal Insufficiency - urine Retroperitoneal Space Risk Factors Shock - chemically induced Time Factors Treatment Outcome |
| title | Bleeding complication due to accumulation of low-molecular-weight heparin in a patient with renal insufficiency |
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