Modulation of oxidative damage by nitroxide free radicals

Piperidine nitroxides like 2,2,6,6-tetramethyl-1-piperidinyloxy (TEMPO) are persistent free radicals in non-acidic aqueous solutions and organic solvents that may have value as therapeutic agents in medicine. In biological environments, they undergo mostly reduction to stable hydroxylamines but can...

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Veröffentlicht in:	Free radical research 2007-01, Vol.41 (3), p.303-315
Hauptverfasser:	Dragutan, Ileana, Mehlhorn, Rolf J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants - chemistry Cyclic N-Oxides - chemistry Ferricyanides - chemistry Free Radicals - chemistry Nitrogen Oxides - chemistry nitroxide Organic Chemicals - chemistry Oxidation-Reduction oxidative damage Oxidative Stress Oxoammonium Piperidines - chemistry Quaternary Ammonium Compounds - chemistry Solutions - chemistry Sulfhydryl Compounds - chemistry thiol oxidation Water - chemistry
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