Photodynamic therapy as a new treatment of cutaneous leishmaniasis
We assessed the effectiveness of photodynamic therapy in the treatment of cutaneous leishmaniasis in 5 patients. Delta-aminolevulinic acid in a water-in-oil emulsion was applied to the lesions and irradiation was performed. The treatment was repeated once a week for a month. Each time, direct smears...
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| Veröffentlicht in: | Eastern Mediterranean health journal 2006-11, Vol.12 (6), p.902 |
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| container_title | Eastern Mediterranean health journal |
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| creator | Ghaffarifar, F Jorjani, O Mirshams, M Miranbaygi, M H Hosseini, Z K |
| description | We assessed the effectiveness of photodynamic therapy in the treatment of cutaneous leishmaniasis in 5 patients. Delta-aminolevulinic acid in a water-in-oil emulsion was applied to the lesions and irradiation was performed. The treatment was repeated once a week for a month. Each time, direct smears of the lesions were prepared and cultured in NNN media. In direct staining, smears showed no amastigotes after 1 or 2 sessions. Healing and cosmetic outcome after photodynamic therapy was excellent. Only mild local inflammatory reaction was noted with no scarring and 4 months after the last treatment session, there were no clinical signs of recurrence. |
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Delta-aminolevulinic acid in a water-in-oil emulsion was applied to the lesions and irradiation was performed. The treatment was repeated once a week for a month. Each time, direct smears of the lesions were prepared and cultured in NNN media. In direct staining, smears showed no amastigotes after 1 or 2 sessions. Healing and cosmetic outcome after photodynamic therapy was excellent. Only mild local inflammatory reaction was noted with no scarring and 4 months after the last treatment session, there were no clinical signs of recurrence.</description><subject>Aminolevulinic Acid - adverse effects</subject><subject>Aminolevulinic Acid - therapeutic use</subject><subject>Drug Administration Schedule</subject><subject>Drug Monitoring</subject><subject>Humans</subject><subject>Hyperpigmentation - chemically induced</subject><subject>Inflammation - chemically induced</subject><subject>Iran</subject><subject>Leishmaniasis, Cutaneous - drug therapy</subject><subject>Leishmaniasis, Cutaneous - parasitology</subject><subject>Leishmaniasis, Cutaneous - pathology</subject><subject>Parasitology</subject><subject>Photochemotherapy - adverse effects</subject><subject>Photochemotherapy - methods</subject><subject>Photosensitizing Agents - adverse effects</subject><subject>Photosensitizing Agents - therapeutic use</subject><subject>Recurrence</subject><subject>Treatment Outcome</subject><subject>Wound Healing</subject><issn>1020-3397</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1j8tKAzEUQLNQ2tr6C5IfGEhyo5MstfiCQl3outwkN8xIkxkmGWT-XkFdnc3hwLlgGymUaABsu2ZXpXwKoYzRasXWsgUAA2bDHt66oQ5hyZh6z2tHE44Lx8KRZ_ridSKsiXLlQ-R-rphpmAs_U1-6hLnH0pcdu4x4LnT9xy37eHp83780h-Pz6_7-0IxS6dpI72Ib6dYaKaRxWkdN1iJ4wACo71Bia5VyQunwYwFJ8MpF5wJ6CMLDlt38dsfZJQqnceoTTsvpfwa-AY3hRlU</recordid><startdate>200611</startdate><enddate>200611</enddate><creator>Ghaffarifar, F</creator><creator>Jorjani, O</creator><creator>Mirshams, M</creator><creator>Miranbaygi, M H</creator><creator>Hosseini, Z K</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>200611</creationdate><title>Photodynamic therapy as a new treatment of cutaneous leishmaniasis</title><author>Ghaffarifar, F ; Jorjani, O ; Mirshams, M ; Miranbaygi, M H ; Hosseini, Z K</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p124t-1cbf7fe5981018b44f4e99a3c3ad3a46a1a7922b024de593e13c2bfbbdac3d0c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Aminolevulinic Acid - adverse effects</topic><topic>Aminolevulinic Acid - therapeutic use</topic><topic>Drug Administration Schedule</topic><topic>Drug Monitoring</topic><topic>Humans</topic><topic>Hyperpigmentation - chemically induced</topic><topic>Inflammation - chemically induced</topic><topic>Iran</topic><topic>Leishmaniasis, Cutaneous - drug therapy</topic><topic>Leishmaniasis, Cutaneous - parasitology</topic><topic>Leishmaniasis, Cutaneous - pathology</topic><topic>Parasitology</topic><topic>Photochemotherapy - adverse effects</topic><topic>Photochemotherapy - methods</topic><topic>Photosensitizing Agents - adverse effects</topic><topic>Photosensitizing Agents - therapeutic use</topic><topic>Recurrence</topic><topic>Treatment Outcome</topic><topic>Wound Healing</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ghaffarifar, F</creatorcontrib><creatorcontrib>Jorjani, O</creatorcontrib><creatorcontrib>Mirshams, M</creatorcontrib><creatorcontrib>Miranbaygi, M H</creatorcontrib><creatorcontrib>Hosseini, Z K</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Eastern Mediterranean health journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ghaffarifar, F</au><au>Jorjani, O</au><au>Mirshams, M</au><au>Miranbaygi, M H</au><au>Hosseini, Z K</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Photodynamic therapy as a new treatment of cutaneous leishmaniasis</atitle><jtitle>Eastern Mediterranean health journal</jtitle><addtitle>East Mediterr Health J</addtitle><date>2006-11</date><risdate>2006</risdate><volume>12</volume><issue>6</issue><spage>902</spage><pages>902-</pages><issn>1020-3397</issn><abstract>We assessed the effectiveness of photodynamic therapy in the treatment of cutaneous leishmaniasis in 5 patients. Delta-aminolevulinic acid in a water-in-oil emulsion was applied to the lesions and irradiation was performed. The treatment was repeated once a week for a month. Each time, direct smears of the lesions were prepared and cultured in NNN media. In direct staining, smears showed no amastigotes after 1 or 2 sessions. Healing and cosmetic outcome after photodynamic therapy was excellent. Only mild local inflammatory reaction was noted with no scarring and 4 months after the last treatment session, there were no clinical signs of recurrence.</abstract><cop>Egypt</cop><pmid>17333838</pmid></addata></record> |
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| identifier | ISSN: 1020-3397 |
| ispartof | Eastern Mediterranean health journal, 2006-11, Vol.12 (6), p.902 |
| issn | 1020-3397 |
| language | eng |
| recordid | cdi_pubmed_primary_17333838 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Aminolevulinic Acid - adverse effects Aminolevulinic Acid - therapeutic use Drug Administration Schedule Drug Monitoring Humans Hyperpigmentation - chemically induced Inflammation - chemically induced Iran Leishmaniasis, Cutaneous - drug therapy Leishmaniasis, Cutaneous - parasitology Leishmaniasis, Cutaneous - pathology Parasitology Photochemotherapy - adverse effects Photochemotherapy - methods Photosensitizing Agents - adverse effects Photosensitizing Agents - therapeutic use Recurrence Treatment Outcome Wound Healing |
| title | Photodynamic therapy as a new treatment of cutaneous leishmaniasis |
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