Lung cancer genetics and pharmacogenomics

Epidermal growth factor receptor (EGFR)-targeted therapies have demonstrated remarkable success in a small subset of non-small cell lung cancer patients. The mechanism of response has been an area of active research, with somatic mutation in a number of genes in the EGFR signal transduction pathway...

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Veröffentlicht in:	Cytogenetic and genome research 2006-11, Vol.115 (3-4), p.298-302
Hauptverfasser:	Joshi, V.A., Kucherlapati, R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - pharmacology Biomarkers, Tumor Exons Gene Dosage Gene Expression Regulation, Neoplastic Genetics Genotype Humans Lung cancer Lung Neoplasms - drug therapy Lung Neoplasms - genetics Mutation Oligonucleotide Array Sequence Analysis Pharmacogenetics - methods Receptor, Epidermal Growth Factor - genetics
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