Stimulation of Erythrocyte Phosphatidylserine Exposure by Paclitaxel

Side effects of cytostatic treatment include development of anemia resulting from either decreased generation or accelerated clearance of circulating erythrocytes. Recent experiments revealed a novel kind of stress-induced erythrocyte death, i.e. eryptosis, which is characterized by enhanced cytosol...

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Veröffentlicht in:	Cellular physiology and biochemistry 2006-01, Vol.18 (1-3), p.151-164
Hauptverfasser:	Lang, Philipp A., Huober, Jens, Bachmann, Cornelia, Kempe, Daniela S., Sobiesiak, Malgorzata, Akel, Ahmad, Niemoeller, Olivier M., Dreischer, Peter, Eisele, Kerstin, Klarl, Barbara A., Gulbins, Erich, Lang, Florian, Wieder, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Combined Chemotherapy Protocols - therapeutic use Blood Cell Count Calcium - metabolism Carboplatin - administration & dosage Cell Size - drug effects Ceramides - metabolism Deoxycytidine - administration & dosage Deoxycytidine - analogs & derivatives Endometrial Neoplasms - blood Endometrial Neoplasms - drug therapy Erythrocytes - drug effects Erythrocytes - metabolism Female Hematocrit Humans Mice Mice, Inbred C57BL Original Paper Osmotic Pressure Ovarian Neoplasms - blood Ovarian Neoplasms - drug therapy Paclitaxel - administration & dosage Paclitaxel - pharmacology Phosphatidylserines - blood Phosphatidylserines - metabolism Protein Binding - drug effects Sphingomyelin Phosphodiesterase - metabolism Time Factors
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