Induction of Signalling in Non-Erythroid Cells by Pharmacological Levels of Erythropoietin

Erythropoiesis is maintained by the hormone erythropoietin (Epo) binding to its cognate receptor (EpoR) on erythroid progenitor cells. The Epo-EpoR interaction initiates a signal transduction process that regulates the survival, growth and differentiation of these cells. Originally perceived as high...

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Veröffentlicht in:	Neuro-degenerative diseases 2006-01, Vol.3 (1-2), p.94-100
Hauptverfasser:	Dunlop, E.A., Percy, M.J., Boland, M.P., Maxwell, A.P., Lappin, T.R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Carcinoma, Non-Small-Cell Lung Cell Division - drug effects Cell Division - physiology Cell Line, Tumor Erythroid Cells - cytology Erythroid Cells - metabolism Erythropoietin - metabolism Erythropoietin - pharmacology GATA1 Transcription Factor - genetics GATA2 Transcription Factor - genetics GATA3 Transcription Factor - genetics GATA4 Transcription Factor - genetics GATA5 Transcription Factor - genetics GATA6 Transcription Factor - genetics Gene Expression - physiology Humans Lung Neoplasms Receptors, Erythropoietin - genetics Receptors, Erythropoietin - metabolism Recombinant Proteins RNA, Messenger - analysis Signal Transduction - drug effects Signal Transduction - physiology Signaling and Stem Cells
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