Neocortical Neurogenesis in Humans Is Restricted to Development

Stem cells generate neurons in discrete regions in the postnatal mammalian brain. However, the extent of neurogenesis in the adult human brain has been difficult to establish. We have taken advantage of the integration of$^{14}C$, generated by nuclear bomb tests during the Cold War, in DNA to establ...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2006-08, Vol.103 (33), p.12564-12568
Hauptverfasser:	Bhardwaj, Ratan D., Curtis, Maurice A., Spalding, Kirsty L., Buchholz, Bruce A., Fink, David, Björk-Eriksson, Thomas, Nordborg, Claes, Gage, Fred H., Druid, Henrik, Eriksson, Peter S., Frisén, Jonas
Format:	Artikel
Sprache:	eng
Schlagworte:	80 and over Adults Aged Aged, 80 and over Aging Aging - physiology Animals Antimetabolites Antimetabolites - metabolism Atmosphere Atmospherics Autopsy Biological Sciences Brain Bromodeoxyuridine Bromodeoxyuridine - metabolism Carbon Radioisotopes Carbon Radioisotopes - metabolism Cell nucleus Cellular biology Cellular immunity cytology embryology growth & development Human body Humans Medical and Health Sciences Medicin och hälsovetenskap metabolism Middle Aged Neocortex Neocortex - cytology Neocortex - embryology Neocortex - growth & development Neurogenesis Neurons Nuclear Warfare physiology Radiocarbon Rodents Stem Cells Stem Cells - cytology Stem Cells - physiology Time Factors
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