Inhibition of nitric oxide and reactive oxygen species production improves the ability of a sunscreen to protect from sunburn, immunosuppression and photocarcinogenesis

Summary Background More effective strategies are required for the prevention of skin cancer, which is caused by ultraviolet (UV) radiation in sunlight. Sunscreens containing UV filters or reflectors offer some protection from sunlight. Pharmacologically active compounds that reduce UV damage offer...

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Veröffentlicht in:	British journal of dermatology (1951) 2006-08, Vol.155 (2), p.408-415
Hauptverfasser:	Russo, P.A.J., Halliday, G.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	2,2'-Dipyridyl - pharmacology Animals Biological and medical sciences Burns Cell Transformation, Neoplastic - drug effects Cell Transformation, Neoplastic - metabolism Cell Transformation, Neoplastic - radiation effects Chelating Agents - pharmacology Dermatology Diseases of the skin. Cosmetics Enzyme Inhibitors - pharmacology Female Immune Tolerance - drug effects Medical sciences Mice Mice, Hairless Neoplasms, Radiation-Induced - metabolism Neoplasms, Radiation-Induced - prevention & control nitric oxide Nitric Oxide - antagonists & inhibitors Nitric Oxide - biosynthesis omega-N-Methylarginine - pharmacology Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) reactive oxygen species Reactive Oxygen Species - antagonists & inhibitors Reactive Oxygen Species - metabolism skin cancer Skin Neoplasms - etiology Skin Neoplasms - metabolism Skin Neoplasms - prevention & control Sunburn - prevention & control sunlight Sunscreening Agents - chemistry Sunscreening Agents - pharmacology sunscreens Traumas. Diseases due to physical agents Tumors of the skin and soft tissue. Premalignant lesions ultraviolet radiation Ultraviolet Rays - adverse effects
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