A Case of Chondrosarcoma Developing in a Recurrent Retroperitoneal Mass after Chemotherapy for Testicular Germ Cell Tumor
Teratomas with malignant transformation occur in a small proportion of patients with metastatic germ cell tumors treated with platinum-based chemotherapy. Chondrosarcoma has rarely been reported as a component of the second non-germ cell malignancy. We report the case of a 37-year-old man who develo...
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Veröffentlicht in: | Urologia internationalis 2006-01, Vol.77 (1), p.86-88 |
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creator | Assimakopoulos, Stelios F. Koutras, Angelos Ravazoula, Panayiota Makatsoris, Thomas Petsas, Theodore Iconomou, Gregoris Nikolopoulou, Vassiliki Kalofonos, Haralabos P. |
description | Teratomas with malignant transformation occur in a small proportion of patients with metastatic germ cell tumors treated with platinum-based chemotherapy. Chondrosarcoma has rarely been reported as a component of the second non-germ cell malignancy. We report the case of a 37-year-old man who developed a chondrosarcoma in a recurrent retroperitoneal mass after chemotherapy for testicular germ cell tumor. Malignant transformation of the retroperitoneal teratomatous mass occurred in the absence of any symptoms or clinical signs, elevation in serum tumor markers, or the presence of atypical elements in previously resected specimens, suggesting the need for close radiographic follow-up of these patients. |
doi_str_mv | 10.1159/000092942 |
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Chondrosarcoma has rarely been reported as a component of the second non-germ cell malignancy. We report the case of a 37-year-old man who developed a chondrosarcoma in a recurrent retroperitoneal mass after chemotherapy for testicular germ cell tumor. Malignant transformation of the retroperitoneal teratomatous mass occurred in the absence of any symptoms or clinical signs, elevation in serum tumor markers, or the presence of atypical elements in previously resected specimens, suggesting the need for close radiographic follow-up of these patients.</description><identifier>ISSN: 0042-1138</identifier><identifier>EISSN: 1423-0399</identifier><identifier>DOI: 10.1159/000092942</identifier><identifier>PMID: 16825823</identifier><language>eng</language><publisher>Basel, Switzerland</publisher><subject>Adult ; Case Report ; Chondrosarcoma - diagnosis ; Humans ; Male ; Neoplasm Recurrence, Local - diagnosis ; Neoplasms, Germ Cell and Embryonal - drug therapy ; Neoplasms, Second Primary - diagnosis ; Retroperitoneal Neoplasms - diagnosis ; Testicular Neoplasms - drug therapy</subject><ispartof>Urologia internationalis, 2006-01, Vol.77 (1), p.86-88</ispartof><rights>2006 S. 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Chondrosarcoma has rarely been reported as a component of the second non-germ cell malignancy. We report the case of a 37-year-old man who developed a chondrosarcoma in a recurrent retroperitoneal mass after chemotherapy for testicular germ cell tumor. Malignant transformation of the retroperitoneal teratomatous mass occurred in the absence of any symptoms or clinical signs, elevation in serum tumor markers, or the presence of atypical elements in previously resected specimens, suggesting the need for close radiographic follow-up of these patients.</description><subject>Adult</subject><subject>Case Report</subject><subject>Chondrosarcoma - diagnosis</subject><subject>Humans</subject><subject>Male</subject><subject>Neoplasm Recurrence, Local - diagnosis</subject><subject>Neoplasms, Germ Cell and Embryonal - drug therapy</subject><subject>Neoplasms, Second Primary - diagnosis</subject><subject>Retroperitoneal Neoplasms - diagnosis</subject><subject>Testicular Neoplasms - drug therapy</subject><issn>0042-1138</issn><issn>1423-0399</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpt0M9LwzAUB_Agis7pwbMgwZuHan6sW3McVedgKsh2Lm_ty6y2TXnphP33RjfmxVwSHh--4X0Zu5DiVsrY3IlwjDIDdcB6cqB0JLQxh6wnxEBFUurkhJ16_yFEwGZ0zE7kMFFxonSPbcY8BY_cWZ6-u6Yg54FyVwO_xy-sXFs2K142HPgb5msibLrw6si1SGXnGoSKP4P3HGyHFDKwdt07ErQbbh3xOfquzNcVEJ8g1TzFquLzde3ojB1ZqDye7-4-Wzw-zNOnaPY6mabjWZRrLboIlZBmZIcQg5Q2MTC0uVIQJghQ6CKJYaSWOehEK1wOddh5kCTKxmJkC4iN7rObbW4edvOENmuprIE2mRTZT33Zvr5gr7a2XS9rLP7krq8ArrfgE2iFtAeL6ctvQtYWNqDLf9H2j284ooA0</recordid><startdate>20060101</startdate><enddate>20060101</enddate><creator>Assimakopoulos, Stelios F.</creator><creator>Koutras, Angelos</creator><creator>Ravazoula, Panayiota</creator><creator>Makatsoris, Thomas</creator><creator>Petsas, Theodore</creator><creator>Iconomou, Gregoris</creator><creator>Nikolopoulou, Vassiliki</creator><creator>Kalofonos, Haralabos P.</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20060101</creationdate><title>A Case of Chondrosarcoma Developing in a Recurrent Retroperitoneal Mass after Chemotherapy for Testicular Germ Cell Tumor</title><author>Assimakopoulos, Stelios F. ; Koutras, Angelos ; Ravazoula, Panayiota ; Makatsoris, Thomas ; Petsas, Theodore ; Iconomou, Gregoris ; Nikolopoulou, Vassiliki ; Kalofonos, Haralabos P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c330t-e20197f6a5a11f89a6fc22a7f6eaad3d85a72bca3832eb630044882f507fda593</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Adult</topic><topic>Case Report</topic><topic>Chondrosarcoma - diagnosis</topic><topic>Humans</topic><topic>Male</topic><topic>Neoplasm Recurrence, Local - diagnosis</topic><topic>Neoplasms, Germ Cell and Embryonal - drug therapy</topic><topic>Neoplasms, Second Primary - diagnosis</topic><topic>Retroperitoneal Neoplasms - diagnosis</topic><topic>Testicular Neoplasms - drug therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Assimakopoulos, Stelios F.</creatorcontrib><creatorcontrib>Koutras, Angelos</creatorcontrib><creatorcontrib>Ravazoula, Panayiota</creatorcontrib><creatorcontrib>Makatsoris, Thomas</creatorcontrib><creatorcontrib>Petsas, Theodore</creatorcontrib><creatorcontrib>Iconomou, Gregoris</creatorcontrib><creatorcontrib>Nikolopoulou, Vassiliki</creatorcontrib><creatorcontrib>Kalofonos, Haralabos P.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Urologia internationalis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Assimakopoulos, Stelios F.</au><au>Koutras, Angelos</au><au>Ravazoula, Panayiota</au><au>Makatsoris, Thomas</au><au>Petsas, Theodore</au><au>Iconomou, Gregoris</au><au>Nikolopoulou, Vassiliki</au><au>Kalofonos, Haralabos P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Case of Chondrosarcoma Developing in a Recurrent Retroperitoneal Mass after Chemotherapy for Testicular Germ Cell Tumor</atitle><jtitle>Urologia internationalis</jtitle><addtitle>Urol Int</addtitle><date>2006-01-01</date><risdate>2006</risdate><volume>77</volume><issue>1</issue><spage>86</spage><epage>88</epage><pages>86-88</pages><issn>0042-1138</issn><eissn>1423-0399</eissn><abstract>Teratomas with malignant transformation occur in a small proportion of patients with metastatic germ cell tumors treated with platinum-based chemotherapy. Chondrosarcoma has rarely been reported as a component of the second non-germ cell malignancy. We report the case of a 37-year-old man who developed a chondrosarcoma in a recurrent retroperitoneal mass after chemotherapy for testicular germ cell tumor. Malignant transformation of the retroperitoneal teratomatous mass occurred in the absence of any symptoms or clinical signs, elevation in serum tumor markers, or the presence of atypical elements in previously resected specimens, suggesting the need for close radiographic follow-up of these patients.</abstract><cop>Basel, Switzerland</cop><pmid>16825823</pmid><doi>10.1159/000092942</doi><tpages>3</tpages></addata></record> |
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source | MEDLINE; Karger Journals |
subjects | Adult Case Report Chondrosarcoma - diagnosis Humans Male Neoplasm Recurrence, Local - diagnosis Neoplasms, Germ Cell and Embryonal - drug therapy Neoplasms, Second Primary - diagnosis Retroperitoneal Neoplasms - diagnosis Testicular Neoplasms - drug therapy |
title | A Case of Chondrosarcoma Developing in a Recurrent Retroperitoneal Mass after Chemotherapy for Testicular Germ Cell Tumor |
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