Nicotine, but neither the alpha4beta2 ligand RJR2403 nor an alpha7 nAChR subtype selective agonist, protects against a partial 6-hydroxydopamine lesion of the rat median forebrain bundle

Although previous studies suggest nicotine protects against a 6-hydroxydopamine (6-OHDA)-induced lesion of the nigrostriatal tract in rats, it is not known whether functional motor recovery occurs or which nicotinic acetylcholine receptor (nAChR) subtypes mediate this effect. These issues were inves...

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Veröffentlicht in:Neuropharmacology 2006-09, Vol.51 (3), p.506
Hauptverfasser: Visanji, N P, O'Neill, M J, Duty, S
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Sprache:eng
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