Structure-activity relationships of salicylic acid and its analogs in the inhibitory action on beta-lactamase

Nineteen compounds related to salicylic acid were evaluated for their in vitro activity of inhibiting beta-lactamase isolated from a resistant strain of Pseudomonas aeruginosa, and their structure-activity relationships were examined. Nitrocefin method was used. The 50% inhibitory concentration (IC5...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Yao hsüeh hsüeh pao 2006-03, Vol.41 (3), p.230
Hauptverfasser:	Yang, Zai-chang, Yang, Xiao-sheng, Wang, Bo-chu, Sun, Qian-yun
Format:	Artikel
Sprache:	chi
Schlagworte:	Anti-Bacterial Agents - chemical synthesis Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology beta-Lactamases - isolation & purification beta-Lactamases - metabolism Cephalosporins - metabolism Inhibitory Concentration 50 Pseudomonas aeruginosa - enzymology Salicylates - chemical synthesis Salicylates - chemistry Salicylates - pharmacology Structure-Activity Relationship
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!