Cryoglobulinemic syndrome: presentation of four cases with skin involvement
Cryoglobulins are serum immunoglobulins that precipitate reversibly when the serum is cooled below 371 degrees C. In cryoglobulinemic syndrome, a multitude of organs can be involved, but many patients suffer from a moderate, chronic disease consisting of palpable purpura, arthralgia and fatigue. Ski...
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| Veröffentlicht in: | Actas dermo-sifiliográficas 2006-03, Vol.97 (2), p.126 |
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| container_title | Actas dermo-sifiliográficas |
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| creator | Suárez-Amor, Oscar Sánchez-Aguilar, Dolores Labandeira, Javier Pereiro, Jr, Manuel Toribio, Jaime |
| description | Cryoglobulins are serum immunoglobulins that precipitate reversibly when the serum is cooled below 371 degrees C. In cryoglobulinemic syndrome, a multitude of organs can be involved, but many patients suffer from a moderate, chronic disease consisting of palpable purpura, arthralgia and fatigue. Skin involvement is especially useful in aiding early recognition of this entity. We present four patients with cryoglobulinemic syndrome and skin lesions, in whom it was not possible to find an etiological or associated factor. We discuss the etiopathogenesis, clinical and pathological findings, treatment and prognosis of this entity. |
| doi_str_mv | 10.1016/S0001-7310(06)73364-6 |
| format | Article |
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In cryoglobulinemic syndrome, a multitude of organs can be involved, but many patients suffer from a moderate, chronic disease consisting of palpable purpura, arthralgia and fatigue. Skin involvement is especially useful in aiding early recognition of this entity. We present four patients with cryoglobulinemic syndrome and skin lesions, in whom it was not possible to find an etiological or associated factor. We discuss the etiopathogenesis, clinical and pathological findings, treatment and prognosis of this entity.</description><identifier>ISSN: 0001-7310</identifier><identifier>DOI: 10.1016/S0001-7310(06)73364-6</identifier><identifier>PMID: 16595115</identifier><language>spa</language><publisher>Spain</publisher><subject>Adrenal Cortex Hormones - therapeutic use ; Adult ; Aged, 80 and over ; Combined Modality Therapy ; Cryoglobulinemia - complications ; Cryoglobulinemia - diagnosis ; Cryoglobulinemia - drug therapy ; Debridement ; Facial Dermatoses - drug therapy ; Facial Dermatoses - etiology ; Female ; Foot Dermatoses - drug therapy ; Foot Dermatoses - etiology ; Foot Ulcer - drug therapy ; Foot Ulcer - etiology ; Foot Ulcer - surgery ; Humans ; Immunosuppressive Agents - therapeutic use ; Leg ; Middle Aged ; Pruritus - drug therapy ; Pruritus - etiology ; Recurrence ; Syndrome ; Vasculitis, Leukocytoclastic, Cutaneous - drug therapy ; Vasculitis, Leukocytoclastic, Cutaneous - etiology</subject><ispartof>Actas dermo-sifiliográficas, 2006-03, Vol.97 (2), p.126</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,27929,27930</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16595115$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Suárez-Amor, Oscar</creatorcontrib><creatorcontrib>Sánchez-Aguilar, Dolores</creatorcontrib><creatorcontrib>Labandeira, Javier</creatorcontrib><creatorcontrib>Pereiro, Jr, Manuel</creatorcontrib><creatorcontrib>Toribio, Jaime</creatorcontrib><title>Cryoglobulinemic syndrome: presentation of four cases with skin involvement</title><title>Actas dermo-sifiliográficas</title><addtitle>Actas Dermosifiliogr</addtitle><description>Cryoglobulins are serum immunoglobulins that precipitate reversibly when the serum is cooled below 371 degrees C. In cryoglobulinemic syndrome, a multitude of organs can be involved, but many patients suffer from a moderate, chronic disease consisting of palpable purpura, arthralgia and fatigue. Skin involvement is especially useful in aiding early recognition of this entity. We present four patients with cryoglobulinemic syndrome and skin lesions, in whom it was not possible to find an etiological or associated factor. We discuss the etiopathogenesis, clinical and pathological findings, treatment and prognosis of this entity.</description><subject>Adrenal Cortex Hormones - therapeutic use</subject><subject>Adult</subject><subject>Aged, 80 and over</subject><subject>Combined Modality Therapy</subject><subject>Cryoglobulinemia - complications</subject><subject>Cryoglobulinemia - diagnosis</subject><subject>Cryoglobulinemia - drug therapy</subject><subject>Debridement</subject><subject>Facial Dermatoses - drug therapy</subject><subject>Facial Dermatoses - etiology</subject><subject>Female</subject><subject>Foot Dermatoses - drug therapy</subject><subject>Foot Dermatoses - etiology</subject><subject>Foot Ulcer - drug therapy</subject><subject>Foot Ulcer - etiology</subject><subject>Foot Ulcer - surgery</subject><subject>Humans</subject><subject>Immunosuppressive Agents - therapeutic use</subject><subject>Leg</subject><subject>Middle Aged</subject><subject>Pruritus - drug therapy</subject><subject>Pruritus - etiology</subject><subject>Recurrence</subject><subject>Syndrome</subject><subject>Vasculitis, Leukocytoclastic, Cutaneous - drug therapy</subject><subject>Vasculitis, Leukocytoclastic, Cutaneous - etiology</subject><issn>0001-7310</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9j0tLxDAcxHNQ3HX1Iyg56qH6T_NqvUnxhQse1POSpIlG26Qk7cp-ews-TsMMP4YZhE4IXBAg4vIZAEghKYEzEOeSUsEKsYeW__ECHeb8AVByCuIALYjgNSeEL9Fjk3bxrYt66nywvTc470KbYm-v8JBstmFUo48BR4ddnBI2KtuMv_z4jvOnD9iHbey2tp_BI7TvVJft8a-u0OvtzUtzX6yf7h6a63UxEKjGQjnJrVLzNqvbthJUOssEU6wUhjtlHKVSaMmYLQ3UVVsrpqiURtfUzFbTFTr96R0m3dt2MyTfq7Tb_L2i3_UST9k</recordid><startdate>200603</startdate><enddate>200603</enddate><creator>Suárez-Amor, Oscar</creator><creator>Sánchez-Aguilar, Dolores</creator><creator>Labandeira, Javier</creator><creator>Pereiro, Jr, Manuel</creator><creator>Toribio, Jaime</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>200603</creationdate><title>Cryoglobulinemic syndrome: presentation of four cases with skin involvement</title><author>Suárez-Amor, Oscar ; Sánchez-Aguilar, Dolores ; Labandeira, Javier ; Pereiro, Jr, Manuel ; Toribio, Jaime</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p108t-af75eaa001ebdd8637fe464a426c5facf3376b744e2c098d9a4a377cb93c98db3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>spa</language><creationdate>2006</creationdate><topic>Adrenal Cortex Hormones - therapeutic use</topic><topic>Adult</topic><topic>Aged, 80 and over</topic><topic>Combined Modality Therapy</topic><topic>Cryoglobulinemia - complications</topic><topic>Cryoglobulinemia - diagnosis</topic><topic>Cryoglobulinemia - drug therapy</topic><topic>Debridement</topic><topic>Facial Dermatoses - drug therapy</topic><topic>Facial Dermatoses - etiology</topic><topic>Female</topic><topic>Foot Dermatoses - drug therapy</topic><topic>Foot Dermatoses - etiology</topic><topic>Foot Ulcer - drug therapy</topic><topic>Foot Ulcer - etiology</topic><topic>Foot Ulcer - surgery</topic><topic>Humans</topic><topic>Immunosuppressive Agents - therapeutic use</topic><topic>Leg</topic><topic>Middle Aged</topic><topic>Pruritus - drug therapy</topic><topic>Pruritus - etiology</topic><topic>Recurrence</topic><topic>Syndrome</topic><topic>Vasculitis, Leukocytoclastic, Cutaneous - drug therapy</topic><topic>Vasculitis, Leukocytoclastic, Cutaneous - etiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Suárez-Amor, Oscar</creatorcontrib><creatorcontrib>Sánchez-Aguilar, Dolores</creatorcontrib><creatorcontrib>Labandeira, Javier</creatorcontrib><creatorcontrib>Pereiro, Jr, Manuel</creatorcontrib><creatorcontrib>Toribio, Jaime</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Actas dermo-sifiliográficas</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Suárez-Amor, Oscar</au><au>Sánchez-Aguilar, Dolores</au><au>Labandeira, Javier</au><au>Pereiro, Jr, Manuel</au><au>Toribio, Jaime</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cryoglobulinemic syndrome: presentation of four cases with skin involvement</atitle><jtitle>Actas dermo-sifiliográficas</jtitle><addtitle>Actas Dermosifiliogr</addtitle><date>2006-03</date><risdate>2006</risdate><volume>97</volume><issue>2</issue><spage>126</spage><pages>126-</pages><issn>0001-7310</issn><abstract>Cryoglobulins are serum immunoglobulins that precipitate reversibly when the serum is cooled below 371 degrees C. In cryoglobulinemic syndrome, a multitude of organs can be involved, but many patients suffer from a moderate, chronic disease consisting of palpable purpura, arthralgia and fatigue. Skin involvement is especially useful in aiding early recognition of this entity. We present four patients with cryoglobulinemic syndrome and skin lesions, in whom it was not possible to find an etiological or associated factor. We discuss the etiopathogenesis, clinical and pathological findings, treatment and prognosis of this entity.</abstract><cop>Spain</cop><pmid>16595115</pmid><doi>10.1016/S0001-7310(06)73364-6</doi></addata></record> |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Adrenal Cortex Hormones - therapeutic use Adult Aged, 80 and over Combined Modality Therapy Cryoglobulinemia - complications Cryoglobulinemia - diagnosis Cryoglobulinemia - drug therapy Debridement Facial Dermatoses - drug therapy Facial Dermatoses - etiology Female Foot Dermatoses - drug therapy Foot Dermatoses - etiology Foot Ulcer - drug therapy Foot Ulcer - etiology Foot Ulcer - surgery Humans Immunosuppressive Agents - therapeutic use Leg Middle Aged Pruritus - drug therapy Pruritus - etiology Recurrence Syndrome Vasculitis, Leukocytoclastic, Cutaneous - drug therapy Vasculitis, Leukocytoclastic, Cutaneous - etiology |
| title | Cryoglobulinemic syndrome: presentation of four cases with skin involvement |
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