Antimycobacterial brominated metabolites from two species of marine sponges

Abstract A screening of 500 crude extracts of marine invertebrates against the growth of MYCOBACTERIUM TUBERCULOSIS H37Rv yielded MeOH extracts of the sponges APLYSINA CAULIFORMIS and PACHYCHALINA sp. with significant activity. Further bioassay-guided fractionation of both crude extracts led to the...

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Veröffentlicht in:	Planta medica 2006-04, Vol.72 (5), p.437-441
Hauptverfasser:	Oliveira, M.F. de, Oliveira, J.H.H.L. de, Galetti, F.C.S, Souza, A.O. de, Silva, C.L, Hajdu, E, Peixinho, S, Berlinck, R.G.S
Format:	Artikel
Sprache:	eng
Schlagworte:	animal pathogenic bacteria Animals Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use antibacterial properties Aplysina cauliformis azoles Biological and medical sciences deoxyfistularin fistularin General pharmacology human health Humans Inhibitory Concentration 50 Macrophages - drug effects Medical sciences Microbial Sensitivity Tests Mycobacterium tuberculosis Mycobacterium tuberculosis - drug effects Original Paper Pachychalina Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments phenylacetic acid Phytotherapy Porifera Porifera - metabolism
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