Monoclonal Antibody Detection of CD46 Clustering beneath Neisseria gonorrhoeae Microcolonies

CD46 (membrane cofactor protein), a complement-regulatory protein that participates in innate and acquired immunity, also serves as a receptor for viral and bacterial pathogens. CD46 isoforms terminate in one of two cytoplasmic tails, Cyt1 or Cyt2, which differ in signaling and trafficking propertie...

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Veröffentlicht in:	Infection and Immunity 2006-04, Vol.74 (4), p.2428-2435
Hauptverfasser:	Weyand, Nathan J, Lee, Shaun W, Higashi, Dustin L, Cawley, Daniel, Yoshihara, Paul, So, Magdalene
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Antibodies, Monoclonal - biosynthesis Antibodies, Monoclonal - metabolism Applied microbiology Bacterial Adhesion - immunology Bacteriology Biological and medical sciences Cell Line, Tumor Cell Polarity - immunology Cellular Microbiology: Pathogen-Host Cell Molecular Interactions Cytoplasm - immunology Epithelial Cells - immunology Epithelial Cells - metabolism Fundamental and applied biological sciences. Psychology Humans Membrane Cofactor Protein - genetics Membrane Cofactor Protein - immunology Membrane Cofactor Protein - metabolism Microbiology Microscopy, Fluorescence Miscellaneous Molecular Sequence Data Neisseria gonorrhoeae Neisseria gonorrhoeae - immunology Neisseria gonorrhoeae - isolation & purification Neisseria gonorrhoeae - metabolism Protein Isoforms - genetics Protein Isoforms - immunology Protein Isoforms - metabolism Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
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