Feasibility of delivering grid therapy using a multileaf collimator
The feasibility of using a multileaf collimator (MLC) for grid therapy is demonstrated in this study. Grids with the projected field openings of 10 mm × 10 mm and 5 mm × 5 mm were created using multiple MLC-shaped fields. The deposited doses were measured with films at different depths in a solid wa...
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Veröffentlicht in: | Medical physics (Lancaster) 2006-01, Vol.33 (1), p.76-82 |
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creator | Ha, Jonathan K. Zhang, Guowei Naqvi, Shahid A. Regine, William F. Yu, Cedric X. |
description | The feasibility of using a multileaf collimator (MLC) for grid therapy is demonstrated in this study. Grids with the projected field openings of
10
mm
×
10
mm
and
5
mm
×
5
mm
were created using multiple MLC-shaped fields. The deposited doses were measured with films at different depths in a solid water phantom and compared to those of Cerrobend grid collimators of similar hole sizes and hole separations. At the depth of maximum dose
(
d
max
)
, the valley-to-peak dose ratios of the MLC grids were found to be about 11% and 19% for the respective
10
mm
×
10
mm
and
5
mm
×
5
mm
grid openings, and those of the corresponding grid blocks were about 15% and 20%. To quantify the dose contributed by transmission in the blocked areas due to the limited leaf thickness, Monte Carlo simulations (based on convolution/superposition method) were performed to calculate the doses in the solid water phantom using an ideal MLC with no leakage and perfect divergence in both the leaf end and side. About 7% reduction in the valley-to-peak dose ratio was found for both grid sizes at
d
max
. The results clearly showed that MLCs can be used to provide grid treatments with at least as good dosimetric properties as those of the Cerrobend grid blocks, though the former would in general require a longer delivery time. |
doi_str_mv | 10.1118/1.2140116 |
format | Article |
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10
mm
×
10
mm
and
5
mm
×
5
mm
were created using multiple MLC-shaped fields. The deposited doses were measured with films at different depths in a solid water phantom and compared to those of Cerrobend grid collimators of similar hole sizes and hole separations. At the depth of maximum dose
(
d
max
)
, the valley-to-peak dose ratios of the MLC grids were found to be about 11% and 19% for the respective
10
mm
×
10
mm
and
5
mm
×
5
mm
grid openings, and those of the corresponding grid blocks were about 15% and 20%. To quantify the dose contributed by transmission in the blocked areas due to the limited leaf thickness, Monte Carlo simulations (based on convolution/superposition method) were performed to calculate the doses in the solid water phantom using an ideal MLC with no leakage and perfect divergence in both the leaf end and side. About 7% reduction in the valley-to-peak dose ratio was found for both grid sizes at
d
max
. The results clearly showed that MLCs can be used to provide grid treatments with at least as good dosimetric properties as those of the Cerrobend grid blocks, though the former would in general require a longer delivery time.</description><identifier>ISSN: 0094-2405</identifier><identifier>EISSN: 2473-4209</identifier><identifier>DOI: 10.1118/1.2140116</identifier><identifier>PMID: 16485412</identifier><identifier>CODEN: MPHYA6</identifier><language>eng</language><publisher>United States: American Association of Physicists in Medicine</publisher><subject>Ancillary equipment ; Cancer ; Collimation ; COLLIMATORS ; COMPUTERIZED SIMULATION ; Dose Fractionation ; dosimetry ; Drug delivery ; Equipment Design ; Equipment Failure Analysis ; Feasibility Studies ; FILM DOSIMETRY ; FRACTIONATION ; grid therapy ; MONTE CARLO METHOD ; Monte Carlo methods ; multileaf collimator ; Multileaf collimators ; PHANTOMS ; Photon scattering ; Photons ; Radiation Dosage ; RADIATION DOSES ; radiation therapy ; Radiation treatment ; RADIOLOGY AND NUCLEAR MEDICINE ; Radiometry - methods ; RADIOTHERAPY ; Radiotherapy, Conformal - instrumentation ; Radiotherapy, Conformal - methods ; Scattering, Radiation ; spatial fractionation ; THICKNESS ; Treatment strategy ; X‐ray scattering</subject><ispartof>Medical physics (Lancaster), 2006-01, Vol.33 (1), p.76-82</ispartof><rights>American Association of Physicists in Medicine</rights><rights>2006 American Association of Physicists in Medicine</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5406-ceabe65494572b300155af654c83068323184463d202bd76326116447d2c6bea3</citedby><cites>FETCH-LOGICAL-c5406-ceabe65494572b300155af654c83068323184463d202bd76326116447d2c6bea3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1118%2F1.2140116$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1118%2F1.2140116$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>230,314,780,784,885,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16485412$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink><backlink>$$Uhttps://www.osti.gov/biblio/20774988$$D View this record in Osti.gov$$Hfree_for_read</backlink></links><search><creatorcontrib>Ha, Jonathan K.</creatorcontrib><creatorcontrib>Zhang, Guowei</creatorcontrib><creatorcontrib>Naqvi, Shahid A.</creatorcontrib><creatorcontrib>Regine, William F.</creatorcontrib><creatorcontrib>Yu, Cedric X.</creatorcontrib><title>Feasibility of delivering grid therapy using a multileaf collimator</title><title>Medical physics (Lancaster)</title><addtitle>Med Phys</addtitle><description>The feasibility of using a multileaf collimator (MLC) for grid therapy is demonstrated in this study. Grids with the projected field openings of
10
mm
×
10
mm
and
5
mm
×
5
mm
were created using multiple MLC-shaped fields. The deposited doses were measured with films at different depths in a solid water phantom and compared to those of Cerrobend grid collimators of similar hole sizes and hole separations. At the depth of maximum dose
(
d
max
)
, the valley-to-peak dose ratios of the MLC grids were found to be about 11% and 19% for the respective
10
mm
×
10
mm
and
5
mm
×
5
mm
grid openings, and those of the corresponding grid blocks were about 15% and 20%. To quantify the dose contributed by transmission in the blocked areas due to the limited leaf thickness, Monte Carlo simulations (based on convolution/superposition method) were performed to calculate the doses in the solid water phantom using an ideal MLC with no leakage and perfect divergence in both the leaf end and side. About 7% reduction in the valley-to-peak dose ratio was found for both grid sizes at
d
max
. The results clearly showed that MLCs can be used to provide grid treatments with at least as good dosimetric properties as those of the Cerrobend grid blocks, though the former would in general require a longer delivery time.</description><subject>Ancillary equipment</subject><subject>Cancer</subject><subject>Collimation</subject><subject>COLLIMATORS</subject><subject>COMPUTERIZED SIMULATION</subject><subject>Dose Fractionation</subject><subject>dosimetry</subject><subject>Drug delivery</subject><subject>Equipment Design</subject><subject>Equipment Failure Analysis</subject><subject>Feasibility Studies</subject><subject>FILM DOSIMETRY</subject><subject>FRACTIONATION</subject><subject>grid therapy</subject><subject>MONTE CARLO METHOD</subject><subject>Monte Carlo methods</subject><subject>multileaf collimator</subject><subject>Multileaf collimators</subject><subject>PHANTOMS</subject><subject>Photon scattering</subject><subject>Photons</subject><subject>Radiation Dosage</subject><subject>RADIATION DOSES</subject><subject>radiation therapy</subject><subject>Radiation treatment</subject><subject>RADIOLOGY AND NUCLEAR MEDICINE</subject><subject>Radiometry - methods</subject><subject>RADIOTHERAPY</subject><subject>Radiotherapy, Conformal - instrumentation</subject><subject>Radiotherapy, Conformal - methods</subject><subject>Scattering, Radiation</subject><subject>spatial fractionation</subject><subject>THICKNESS</subject><subject>Treatment strategy</subject><subject>X‐ray scattering</subject><issn>0094-2405</issn><issn>2473-4209</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kF1LwzAUhoMobn5c-Aek4JVC58lH0_ZGkOFUmOiFXoc0TbdI15Skm_Tf29mCA5lXgcNz3pz3QegCwwRjnNziCcEMMOYHaExYTENGID1EY4CUhYRBNEIn3n8CAKcRHKMR5iyJGCZjNJ1p6U1mStO0gS2CXJdmo52pFsHCmTxoltrJug3WfjuSwWpdNqbUsgiULUuzko11Z-iokKXX58N7ij5mD-_Tp3D--vg8vZ-HKmLAQ6VlpnnEUhbFJKMAOIpk0Q1UQoEnlFCcMMZpToBkecwp4V0lxuKcKJ5pSU_RVZ9rfWOEV6bRaqlsVWnVCAJxzNIk6ajrnlLOeu90IWrX3elagUFsdQksBl0de9mz9Tpb6fyXHPx0QNgDX13pdn-SeHkbAu96fnudbIyt9u_smBe2ED_mu4CbfQEb63Y-rPPiP_hv12_PG6F2</recordid><startdate>200601</startdate><enddate>200601</enddate><creator>Ha, Jonathan K.</creator><creator>Zhang, Guowei</creator><creator>Naqvi, Shahid A.</creator><creator>Regine, William F.</creator><creator>Yu, Cedric X.</creator><general>American Association of Physicists in Medicine</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>OTOTI</scope></search><sort><creationdate>200601</creationdate><title>Feasibility of delivering grid therapy using a multileaf collimator</title><author>Ha, Jonathan K. ; Zhang, Guowei ; Naqvi, Shahid A. ; Regine, William F. ; Yu, Cedric X.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5406-ceabe65494572b300155af654c83068323184463d202bd76326116447d2c6bea3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Ancillary equipment</topic><topic>Cancer</topic><topic>Collimation</topic><topic>COLLIMATORS</topic><topic>COMPUTERIZED SIMULATION</topic><topic>Dose Fractionation</topic><topic>dosimetry</topic><topic>Drug delivery</topic><topic>Equipment Design</topic><topic>Equipment Failure Analysis</topic><topic>Feasibility Studies</topic><topic>FILM DOSIMETRY</topic><topic>FRACTIONATION</topic><topic>grid therapy</topic><topic>MONTE CARLO METHOD</topic><topic>Monte Carlo methods</topic><topic>multileaf collimator</topic><topic>Multileaf collimators</topic><topic>PHANTOMS</topic><topic>Photon scattering</topic><topic>Photons</topic><topic>Radiation Dosage</topic><topic>RADIATION DOSES</topic><topic>radiation therapy</topic><topic>Radiation treatment</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>Radiometry - methods</topic><topic>RADIOTHERAPY</topic><topic>Radiotherapy, Conformal - instrumentation</topic><topic>Radiotherapy, Conformal - methods</topic><topic>Scattering, Radiation</topic><topic>spatial fractionation</topic><topic>THICKNESS</topic><topic>Treatment strategy</topic><topic>X‐ray scattering</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ha, Jonathan K.</creatorcontrib><creatorcontrib>Zhang, Guowei</creatorcontrib><creatorcontrib>Naqvi, Shahid A.</creatorcontrib><creatorcontrib>Regine, William F.</creatorcontrib><creatorcontrib>Yu, Cedric X.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>OSTI.GOV</collection><jtitle>Medical physics (Lancaster)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ha, Jonathan K.</au><au>Zhang, Guowei</au><au>Naqvi, Shahid A.</au><au>Regine, William F.</au><au>Yu, Cedric X.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Feasibility of delivering grid therapy using a multileaf collimator</atitle><jtitle>Medical physics (Lancaster)</jtitle><addtitle>Med Phys</addtitle><date>2006-01</date><risdate>2006</risdate><volume>33</volume><issue>1</issue><spage>76</spage><epage>82</epage><pages>76-82</pages><issn>0094-2405</issn><eissn>2473-4209</eissn><coden>MPHYA6</coden><abstract>The feasibility of using a multileaf collimator (MLC) for grid therapy is demonstrated in this study. Grids with the projected field openings of
10
mm
×
10
mm
and
5
mm
×
5
mm
were created using multiple MLC-shaped fields. The deposited doses were measured with films at different depths in a solid water phantom and compared to those of Cerrobend grid collimators of similar hole sizes and hole separations. At the depth of maximum dose
(
d
max
)
, the valley-to-peak dose ratios of the MLC grids were found to be about 11% and 19% for the respective
10
mm
×
10
mm
and
5
mm
×
5
mm
grid openings, and those of the corresponding grid blocks were about 15% and 20%. To quantify the dose contributed by transmission in the blocked areas due to the limited leaf thickness, Monte Carlo simulations (based on convolution/superposition method) were performed to calculate the doses in the solid water phantom using an ideal MLC with no leakage and perfect divergence in both the leaf end and side. About 7% reduction in the valley-to-peak dose ratio was found for both grid sizes at
d
max
. The results clearly showed that MLCs can be used to provide grid treatments with at least as good dosimetric properties as those of the Cerrobend grid blocks, though the former would in general require a longer delivery time.</abstract><cop>United States</cop><pub>American Association of Physicists in Medicine</pub><pmid>16485412</pmid><doi>10.1118/1.2140116</doi><tpages>7</tpages></addata></record> |
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language | eng |
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source | MEDLINE; Access via Wiley Online Library |
subjects | Ancillary equipment Cancer Collimation COLLIMATORS COMPUTERIZED SIMULATION Dose Fractionation dosimetry Drug delivery Equipment Design Equipment Failure Analysis Feasibility Studies FILM DOSIMETRY FRACTIONATION grid therapy MONTE CARLO METHOD Monte Carlo methods multileaf collimator Multileaf collimators PHANTOMS Photon scattering Photons Radiation Dosage RADIATION DOSES radiation therapy Radiation treatment RADIOLOGY AND NUCLEAR MEDICINE Radiometry - methods RADIOTHERAPY Radiotherapy, Conformal - instrumentation Radiotherapy, Conformal - methods Scattering, Radiation spatial fractionation THICKNESS Treatment strategy X‐ray scattering |
title | Feasibility of delivering grid therapy using a multileaf collimator |
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