Feasibility of delivering grid therapy using a multileaf collimator

The feasibility of using a multileaf collimator (MLC) for grid therapy is demonstrated in this study. Grids with the projected field openings of 10 mm × 10 mm and 5 mm × 5 mm were created using multiple MLC-shaped fields. The deposited doses were measured with films at different depths in a solid wa...

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Veröffentlicht in:Medical physics (Lancaster) 2006-01, Vol.33 (1), p.76-82
Hauptverfasser: Ha, Jonathan K., Zhang, Guowei, Naqvi, Shahid A., Regine, William F., Yu, Cedric X.
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container_issue 1
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container_title Medical physics (Lancaster)
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creator Ha, Jonathan K.
Zhang, Guowei
Naqvi, Shahid A.
Regine, William F.
Yu, Cedric X.
description The feasibility of using a multileaf collimator (MLC) for grid therapy is demonstrated in this study. Grids with the projected field openings of 10 mm × 10 mm and 5 mm × 5 mm were created using multiple MLC-shaped fields. The deposited doses were measured with films at different depths in a solid water phantom and compared to those of Cerrobend grid collimators of similar hole sizes and hole separations. At the depth of maximum dose ( d max ) , the valley-to-peak dose ratios of the MLC grids were found to be about 11% and 19% for the respective 10 mm × 10 mm and 5 mm × 5 mm grid openings, and those of the corresponding grid blocks were about 15% and 20%. To quantify the dose contributed by transmission in the blocked areas due to the limited leaf thickness, Monte Carlo simulations (based on convolution/superposition method) were performed to calculate the doses in the solid water phantom using an ideal MLC with no leakage and perfect divergence in both the leaf end and side. About 7% reduction in the valley-to-peak dose ratio was found for both grid sizes at d max . The results clearly showed that MLCs can be used to provide grid treatments with at least as good dosimetric properties as those of the Cerrobend grid blocks, though the former would in general require a longer delivery time.
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Grids with the projected field openings of 10 mm × 10 mm and 5 mm × 5 mm were created using multiple MLC-shaped fields. The deposited doses were measured with films at different depths in a solid water phantom and compared to those of Cerrobend grid collimators of similar hole sizes and hole separations. At the depth of maximum dose ( d max ) , the valley-to-peak dose ratios of the MLC grids were found to be about 11% and 19% for the respective 10 mm × 10 mm and 5 mm × 5 mm grid openings, and those of the corresponding grid blocks were about 15% and 20%. To quantify the dose contributed by transmission in the blocked areas due to the limited leaf thickness, Monte Carlo simulations (based on convolution/superposition method) were performed to calculate the doses in the solid water phantom using an ideal MLC with no leakage and perfect divergence in both the leaf end and side. About 7% reduction in the valley-to-peak dose ratio was found for both grid sizes at d max . 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Zhang, Guowei ; Naqvi, Shahid A. ; Regine, William F. ; Yu, Cedric X.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5406-ceabe65494572b300155af654c83068323184463d202bd76326116447d2c6bea3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Ancillary equipment</topic><topic>Cancer</topic><topic>Collimation</topic><topic>COLLIMATORS</topic><topic>COMPUTERIZED SIMULATION</topic><topic>Dose Fractionation</topic><topic>dosimetry</topic><topic>Drug delivery</topic><topic>Equipment Design</topic><topic>Equipment Failure Analysis</topic><topic>Feasibility Studies</topic><topic>FILM DOSIMETRY</topic><topic>FRACTIONATION</topic><topic>grid therapy</topic><topic>MONTE CARLO METHOD</topic><topic>Monte Carlo methods</topic><topic>multileaf collimator</topic><topic>Multileaf collimators</topic><topic>PHANTOMS</topic><topic>Photon scattering</topic><topic>Photons</topic><topic>Radiation Dosage</topic><topic>RADIATION DOSES</topic><topic>radiation therapy</topic><topic>Radiation treatment</topic><topic>RADIOLOGY AND NUCLEAR MEDICINE</topic><topic>Radiometry - methods</topic><topic>RADIOTHERAPY</topic><topic>Radiotherapy, Conformal - instrumentation</topic><topic>Radiotherapy, Conformal - methods</topic><topic>Scattering, Radiation</topic><topic>spatial fractionation</topic><topic>THICKNESS</topic><topic>Treatment strategy</topic><topic>X‐ray scattering</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ha, Jonathan K.</creatorcontrib><creatorcontrib>Zhang, Guowei</creatorcontrib><creatorcontrib>Naqvi, Shahid A.</creatorcontrib><creatorcontrib>Regine, William F.</creatorcontrib><creatorcontrib>Yu, Cedric X.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>OSTI.GOV</collection><jtitle>Medical physics (Lancaster)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ha, Jonathan K.</au><au>Zhang, Guowei</au><au>Naqvi, Shahid A.</au><au>Regine, William F.</au><au>Yu, Cedric X.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Feasibility of delivering grid therapy using a multileaf collimator</atitle><jtitle>Medical physics (Lancaster)</jtitle><addtitle>Med Phys</addtitle><date>2006-01</date><risdate>2006</risdate><volume>33</volume><issue>1</issue><spage>76</spage><epage>82</epage><pages>76-82</pages><issn>0094-2405</issn><eissn>2473-4209</eissn><coden>MPHYA6</coden><abstract>The feasibility of using a multileaf collimator (MLC) for grid therapy is demonstrated in this study. Grids with the projected field openings of 10 mm × 10 mm and 5 mm × 5 mm were created using multiple MLC-shaped fields. The deposited doses were measured with films at different depths in a solid water phantom and compared to those of Cerrobend grid collimators of similar hole sizes and hole separations. At the depth of maximum dose ( d max ) , the valley-to-peak dose ratios of the MLC grids were found to be about 11% and 19% for the respective 10 mm × 10 mm and 5 mm × 5 mm grid openings, and those of the corresponding grid blocks were about 15% and 20%. To quantify the dose contributed by transmission in the blocked areas due to the limited leaf thickness, Monte Carlo simulations (based on convolution/superposition method) were performed to calculate the doses in the solid water phantom using an ideal MLC with no leakage and perfect divergence in both the leaf end and side. About 7% reduction in the valley-to-peak dose ratio was found for both grid sizes at d max . The results clearly showed that MLCs can be used to provide grid treatments with at least as good dosimetric properties as those of the Cerrobend grid blocks, though the former would in general require a longer delivery time.</abstract><cop>United States</cop><pub>American Association of Physicists in Medicine</pub><pmid>16485412</pmid><doi>10.1118/1.2140116</doi><tpages>7</tpages></addata></record>
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subjects Ancillary equipment
Cancer
Collimation
COLLIMATORS
COMPUTERIZED SIMULATION
Dose Fractionation
dosimetry
Drug delivery
Equipment Design
Equipment Failure Analysis
Feasibility Studies
FILM DOSIMETRY
FRACTIONATION
grid therapy
MONTE CARLO METHOD
Monte Carlo methods
multileaf collimator
Multileaf collimators
PHANTOMS
Photon scattering
Photons
Radiation Dosage
RADIATION DOSES
radiation therapy
Radiation treatment
RADIOLOGY AND NUCLEAR MEDICINE
Radiometry - methods
RADIOTHERAPY
Radiotherapy, Conformal - instrumentation
Radiotherapy, Conformal - methods
Scattering, Radiation
spatial fractionation
THICKNESS
Treatment strategy
X‐ray scattering
title Feasibility of delivering grid therapy using a multileaf collimator
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