Suramin prevents fulminant hepatic failure resulting in reduction of lethality through the suppression of NF-kappaB activity

Suramin is a symmetrical polysulfonated naphthylamine derivative of urea. There have been few studies on the effect of suramin on cytokines. We examined the effects of suramin on production of inflammatory cytokines. We made an acute liver injury model treated with d-galactosamine (GalN) and lipopol...

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