Human Intestinal Circadian Clock: Expression of Clock Genes in Colonocytes Lining the Crypt

Biological clock components have been detected in many epithelial tissues of the digestive tract of mammals (oral mucosa, pancreas, and liver), suggesting the existence of peripheral circadian clocks that may be entrainable by food. Our aim was to investigate the expression of main peripheral clock...

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Veröffentlicht in:	Chronobiology international 2005-01, Vol.22 (6), p.951-961
Hauptverfasser:	Pardini, L., Kaeffer, B., Trubuil, A., Bourreille, A., Galmiche, J.-P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over ARNTL Transcription Factors Basic Helix-Loop-Helix Transcription Factors - genetics Biological Clocks - physiology Cell Cycle Proteins Cell Line, Tumor circadian rhythm Circadian Rhythm - physiology clock genes CLOCK Proteins colon Colon - physiology Colonic Neoplasms ErbB Receptors - genetics Female Gene Expression Regulation Humans Intestinal Mucosa - physiology Large intestine Life Sciences Male Middle Aged Nuclear Proteins - genetics per-1 per-2 Period Circadian Proteins Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics Trans-Activators - genetics Transcription Factors - genetics
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