Multiple Sclerosis Mortality and Patterns of Comorbidity in the United States from 1990 to 2001

Multiple sclerosis (MS) is a neurodegenerative condition that can result in cognitive and physical disability and shortened life expectancy. However, population-based information is lacking regarding the mortality burden from MS in the United States. We investigated trends in MS mortality rates and...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Neuroepidemiology 2006-02, Vol.26 (2), p.102-107
Hauptverfasser: Redelings, Matthew D., McCoy, Lucie, Sorvillo, Frank
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 107
container_issue 2
container_start_page 102
container_title Neuroepidemiology
container_volume 26
creator Redelings, Matthew D.
McCoy, Lucie
Sorvillo, Frank
description Multiple sclerosis (MS) is a neurodegenerative condition that can result in cognitive and physical disability and shortened life expectancy. However, population-based information is lacking regarding the mortality burden from MS in the United States. We investigated trends in MS mortality rates and examined important comorbidities in the United States from 1990 to 2001. MS deaths were matched by age, sex, and race/ethnicity with randomly selected deaths from other conditions for matched odds ratio comparisons. The overall age-adjusted mortality rate from MS was 1.44/100,000 population. MS mortality rates increased throughout the study period. MS mortality rates were higher in whites than in any other racial/ethnic group, followed by Blacks, Hispanics, American Indians/Alaska Natives, and Asians and Pacific Islanders. Observed mortality rates were more than 10 times lower in Asians and Pacific Islanders than in whites. The odds of pressure ulcers, urinary tract infections, and pneumonia/influenza being reported on the death certificate were higher in MS deaths than in matched controls.
doi_str_mv 10.1159/000090444
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmed_primary_16374035</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>20899617</sourcerecordid><originalsourceid>FETCH-LOGICAL-c361t-e6426ebc81c3961a63c8f06b88b7e892aec35a60ef47c5a32f2e85fd4538a1cb3</originalsourceid><addsrcrecordid>eNqF0TtLxTAUB_Agil4fg7MgwUFwqObdZJSLL1AU1Lmk6alW2-aapIPf3si9KLiYJUN-OTk5f4T2KTmlVJozkpchQog1NKOC8YIwotfRjDBJC8kl2ULbMb4RkrE2m2iLKl4KwuUMVXdTn7pFD_jR9RB87CK-8yHZvkuf2I4NfrApQRgj9i2e-8GHumu-z7oRp1fAz2OXoMGPySaIuA1-wNQYgpPHLD-4izZa20fYW-076Pny4ml-XdzeX93Mz28LxxVNBSjBFNROU8eNolZxp1uiaq3rErRhFhyXVhFoRemk5axloGXbCMm1pa7mO-h4WXcR_McEMVVDFx30vR3BT7FSpeKKlfRfmCdncgdlhkd_4Jufwpg_UTHOjBK6ZBmdLJHLo4sB2moRusGGz4qS6jub6iebbA9XBad6gOZXrsLI4GAJ3m14gfADlte_AFK0j5Q</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>232964872</pqid></control><display><type>article</type><title>Multiple Sclerosis Mortality and Patterns of Comorbidity in the United States from 1990 to 2001</title><source>Karger Journals</source><source>MEDLINE</source><creator>Redelings, Matthew D. ; McCoy, Lucie ; Sorvillo, Frank</creator><creatorcontrib>Redelings, Matthew D. ; McCoy, Lucie ; Sorvillo, Frank</creatorcontrib><description>Multiple sclerosis (MS) is a neurodegenerative condition that can result in cognitive and physical disability and shortened life expectancy. However, population-based information is lacking regarding the mortality burden from MS in the United States. We investigated trends in MS mortality rates and examined important comorbidities in the United States from 1990 to 2001. MS deaths were matched by age, sex, and race/ethnicity with randomly selected deaths from other conditions for matched odds ratio comparisons. The overall age-adjusted mortality rate from MS was 1.44/100,000 population. MS mortality rates increased throughout the study period. MS mortality rates were higher in whites than in any other racial/ethnic group, followed by Blacks, Hispanics, American Indians/Alaska Natives, and Asians and Pacific Islanders. Observed mortality rates were more than 10 times lower in Asians and Pacific Islanders than in whites. The odds of pressure ulcers, urinary tract infections, and pneumonia/influenza being reported on the death certificate were higher in MS deaths than in matched controls.</description><identifier>ISSN: 0251-5350</identifier><identifier>EISSN: 1423-0208</identifier><identifier>DOI: 10.1159/000090444</identifier><identifier>PMID: 16374035</identifier><language>eng</language><publisher>Basel, Switzerland: S. Karger AG</publisher><subject>Adolescent ; Adult ; Age Factors ; Aged ; Aged, 80 and over ; Child ; Child, Preschool ; Continental Population Groups ; Ethnic Groups ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Middle Aged ; Mortality - trends ; Multiple Sclerosis - complications ; Multiple Sclerosis - mortality ; Odds Ratio ; Original Paper ; United States - epidemiology</subject><ispartof>Neuroepidemiology, 2006-02, Vol.26 (2), p.102-107</ispartof><rights>2006 S. Karger AG, Basel</rights><rights>Copyright (c) 2006 S. Karger AG, Basel.</rights><rights>Copyright (c) 2006 S. Karger AG, Basel</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c361t-e6426ebc81c3961a63c8f06b88b7e892aec35a60ef47c5a32f2e85fd4538a1cb3</citedby><cites>FETCH-LOGICAL-c361t-e6426ebc81c3961a63c8f06b88b7e892aec35a60ef47c5a32f2e85fd4538a1cb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,2423,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16374035$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Redelings, Matthew D.</creatorcontrib><creatorcontrib>McCoy, Lucie</creatorcontrib><creatorcontrib>Sorvillo, Frank</creatorcontrib><title>Multiple Sclerosis Mortality and Patterns of Comorbidity in the United States from 1990 to 2001</title><title>Neuroepidemiology</title><addtitle>Neuroepidemiology</addtitle><description>Multiple sclerosis (MS) is a neurodegenerative condition that can result in cognitive and physical disability and shortened life expectancy. However, population-based information is lacking regarding the mortality burden from MS in the United States. We investigated trends in MS mortality rates and examined important comorbidities in the United States from 1990 to 2001. MS deaths were matched by age, sex, and race/ethnicity with randomly selected deaths from other conditions for matched odds ratio comparisons. The overall age-adjusted mortality rate from MS was 1.44/100,000 population. MS mortality rates increased throughout the study period. MS mortality rates were higher in whites than in any other racial/ethnic group, followed by Blacks, Hispanics, American Indians/Alaska Natives, and Asians and Pacific Islanders. Observed mortality rates were more than 10 times lower in Asians and Pacific Islanders than in whites. The odds of pressure ulcers, urinary tract infections, and pneumonia/influenza being reported on the death certificate were higher in MS deaths than in matched controls.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Continental Population Groups</subject><subject>Ethnic Groups</subject><subject>Female</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Mortality - trends</subject><subject>Multiple Sclerosis - complications</subject><subject>Multiple Sclerosis - mortality</subject><subject>Odds Ratio</subject><subject>Original Paper</subject><subject>United States - epidemiology</subject><issn>0251-5350</issn><issn>1423-0208</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqF0TtLxTAUB_Agil4fg7MgwUFwqObdZJSLL1AU1Lmk6alW2-aapIPf3si9KLiYJUN-OTk5f4T2KTmlVJozkpchQog1NKOC8YIwotfRjDBJC8kl2ULbMb4RkrE2m2iLKl4KwuUMVXdTn7pFD_jR9RB87CK-8yHZvkuf2I4NfrApQRgj9i2e-8GHumu-z7oRp1fAz2OXoMGPySaIuA1-wNQYgpPHLD-4izZa20fYW-076Pny4ml-XdzeX93Mz28LxxVNBSjBFNROU8eNolZxp1uiaq3rErRhFhyXVhFoRemk5axloGXbCMm1pa7mO-h4WXcR_McEMVVDFx30vR3BT7FSpeKKlfRfmCdncgdlhkd_4Jufwpg_UTHOjBK6ZBmdLJHLo4sB2moRusGGz4qS6jub6iebbA9XBad6gOZXrsLI4GAJ3m14gfADlte_AFK0j5Q</recordid><startdate>200602</startdate><enddate>200602</enddate><creator>Redelings, Matthew D.</creator><creator>McCoy, Lucie</creator><creator>Sorvillo, Frank</creator><general>S. Karger AG</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TK</scope><scope>7U7</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>88I</scope><scope>8AF</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>S0X</scope><scope>7X8</scope></search><sort><creationdate>200602</creationdate><title>Multiple Sclerosis Mortality and Patterns of Comorbidity in the United States from 1990 to 2001</title><author>Redelings, Matthew D. ; McCoy, Lucie ; Sorvillo, Frank</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c361t-e6426ebc81c3961a63c8f06b88b7e892aec35a60ef47c5a32f2e85fd4538a1cb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age Factors</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Continental Population Groups</topic><topic>Ethnic Groups</topic><topic>Female</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Mortality - trends</topic><topic>Multiple Sclerosis - complications</topic><topic>Multiple Sclerosis - mortality</topic><topic>Odds Ratio</topic><topic>Original Paper</topic><topic>United States - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Redelings, Matthew D.</creatorcontrib><creatorcontrib>McCoy, Lucie</creatorcontrib><creatorcontrib>Sorvillo, Frank</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest Psychology</collection><collection>Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>SIRS Editorial</collection><collection>MEDLINE - Academic</collection><jtitle>Neuroepidemiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Redelings, Matthew D.</au><au>McCoy, Lucie</au><au>Sorvillo, Frank</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Multiple Sclerosis Mortality and Patterns of Comorbidity in the United States from 1990 to 2001</atitle><jtitle>Neuroepidemiology</jtitle><addtitle>Neuroepidemiology</addtitle><date>2006-02</date><risdate>2006</risdate><volume>26</volume><issue>2</issue><spage>102</spage><epage>107</epage><pages>102-107</pages><issn>0251-5350</issn><eissn>1423-0208</eissn><abstract>Multiple sclerosis (MS) is a neurodegenerative condition that can result in cognitive and physical disability and shortened life expectancy. However, population-based information is lacking regarding the mortality burden from MS in the United States. We investigated trends in MS mortality rates and examined important comorbidities in the United States from 1990 to 2001. MS deaths were matched by age, sex, and race/ethnicity with randomly selected deaths from other conditions for matched odds ratio comparisons. The overall age-adjusted mortality rate from MS was 1.44/100,000 population. MS mortality rates increased throughout the study period. MS mortality rates were higher in whites than in any other racial/ethnic group, followed by Blacks, Hispanics, American Indians/Alaska Natives, and Asians and Pacific Islanders. Observed mortality rates were more than 10 times lower in Asians and Pacific Islanders than in whites. The odds of pressure ulcers, urinary tract infections, and pneumonia/influenza being reported on the death certificate were higher in MS deaths than in matched controls.</abstract><cop>Basel, Switzerland</cop><pub>S. Karger AG</pub><pmid>16374035</pmid><doi>10.1159/000090444</doi><tpages>6</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0251-5350
ispartof Neuroepidemiology, 2006-02, Vol.26 (2), p.102-107
issn 0251-5350
1423-0208
language eng
recordid cdi_pubmed_primary_16374035
source Karger Journals; MEDLINE
subjects Adolescent
Adult
Age Factors
Aged
Aged, 80 and over
Child
Child, Preschool
Continental Population Groups
Ethnic Groups
Female
Humans
Infant
Infant, Newborn
Male
Middle Aged
Mortality - trends
Multiple Sclerosis - complications
Multiple Sclerosis - mortality
Odds Ratio
Original Paper
United States - epidemiology
title Multiple Sclerosis Mortality and Patterns of Comorbidity in the United States from 1990 to 2001
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-29T18%3A18%3A11IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Multiple%20Sclerosis%20Mortality%20and%20Patterns%20of%20Comorbidity%20in%20the%20United%20States%20from%201990%20to%202001&rft.jtitle=Neuroepidemiology&rft.au=Redelings,%20Matthew%20D.&rft.date=2006-02&rft.volume=26&rft.issue=2&rft.spage=102&rft.epage=107&rft.pages=102-107&rft.issn=0251-5350&rft.eissn=1423-0208&rft_id=info:doi/10.1159/000090444&rft_dat=%3Cproquest_pubme%3E20899617%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=232964872&rft_id=info:pmid/16374035&rfr_iscdi=true