Premature Ovarian Failure in Androgen Receptor-Deficient Mice

Premature ovarian failure (POF) syndrome, an early decline of ovarian function in women, is frequently associated with X chromosome abnormalities ranging from various Xq deletions to complete loss of one of the X chromosomes. However, the genetic locus responsible for the POF remains unknown, and no...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2006-01, Vol.103 (1), p.224-229
Hauptverfasser:	Shiina, Hiroko, Matsumoto, Takahiro, Sato, Takashi, Igarashi, Katsuhide, Miyamoto, Junko, Takemasa, Sayuri, Sakari, Matomo, Takada, Ichiro, Nakamura, Takashi, Metzger, Daniel, Chambon, Pierre, Kanno, Jun, Yoshikawa, Hiroyuki, Kato, Shigeaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgens Animals Biochemistry, Molecular Biology Biological Sciences Blotting, Western Chromosomes Female Female animals Follicles Follicular development Genotypes Granulosa cells Immunohistochemistry Life Sciences Luciferases Mice Mice, Knockout Molecular biology Nucleotides Oligonucleotide Array Sequence Analysis Ovarian Failure, Premature Ovarian Follicle Ovarian Follicle - anatomy & histology Ovarian Follicle - growth & development Ovaries Primary Ovarian Insufficiency - genetics Receptors, Androgen Receptors, Androgen - deficiency Receptors, Androgen - genetics Receptors, Androgen - metabolism Reproductive system Reverse Transcriptase Polymerase Chain Reaction RNA Rodents Sex chromosomes Women X Chromosome X Chromosome - genetics
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