Venous thromboembolism and fractured neck of femur
Summary The post-operative incidence of venous thromboembolism (VTE) is high for patients undergoing hip fracture surgery. Proven prophylactic measures are available although underutilized due to concern on post-operative bleeding with use of anticoagulants. This study retrospectively reviewed the c...
Gespeichert in:
| Veröffentlicht in: | Thrombosis and haemostasis 2005-11, Vol.94 (5), p.991-996 |
|---|---|
| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 996 |
|---|---|
| container_issue | 5 |
| container_start_page | 991 |
| container_title | Thrombosis and haemostasis |
| container_volume | 94 |
| creator | Hitos, Kerry Fletcher, John P. |
| description | Summary
The post-operative incidence of venous thromboembolism (VTE) is high for patients undergoing hip fracture surgery. Proven prophylactic measures are available although underutilized due to concern on post-operative bleeding with use of anticoagulants. This study retrospectively reviewed the clinical incidence of VTE and utilisation of thromboprophylactic protocols over an eight year period. Demographic details, mechanism of injury, VTE risk factors, prophylactic modalities (mechanical and pharmacological), operation duration, mode of anaesthesia, hospital length of stay (LOS) and post-operative complications with particular attention to suspected deep vein thrombosis (DVT) and/or pulmonary embolism (PE) were analysed. Male to female ratio was 1: 2.7 with a median age of 78 years (IQR: 70–86 years) and 83 years (IQR: 77–87 years) respectively (p |
| doi_str_mv | 10.1160/TH04-10-0696 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmed_primary_16363242</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>68908514</sourcerecordid><originalsourceid>FETCH-LOGICAL-c611t-16c6b8c609c29c25707c45a4eeb383671ee74ffb85c69fb618cf155d61ab0d323</originalsourceid><addsrcrecordid>eNqtkEGL1TAURoMozpvRnWvpRjdaTdI0bZcy6Iww4GYUdyG9vaUZm-aZmyr-e1NecUBwJySESw7flxzGngn-RgjN395ec1UKXnLd6QfsIGvdlLrtvj5kB14pXmqp6jN2TnTHudCqqx-zM6ErXUklD0x-wSWsVKQpBt8HzHt25Au7DMUYLaQ14lAsCN-KMBYj-jU-YY9GOxM-3c8L9vnD-9vL6_Lm09XHy3c3JWghUik06L4FzTuQedUNb0DVViH2VVvpRiA2ahz7tgbdjb0WLYyirgctbM-HSlYX7OUp9xjD9xUpGe8IcJ7tgvnJJn-St7VQGXx9AiEGooijOUbnbfxlBDebI7M52obNUcaf77lr73G4h3cpGXixA5bAzlnDAo7uuUY2XMot6NWJS5NDj-YurHHJRv5VCyeaYLIp2RXjn8jdPuWWLN5MFn2gZLcZwpJwSfkiwuR-oHFEKxo6Ijg7G2-XlSC6YzKq4jy3uP_Y0jT87wZDU_hppuTn6jdGyMw1</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>68908514</pqid></control><display><type>article</type><title>Venous thromboembolism and fractured neck of femur</title><source>MEDLINE</source><source>Thieme Connect Journals</source><creator>Hitos, Kerry ; Fletcher, John P.</creator><creatorcontrib>Hitos, Kerry ; Fletcher, John P.</creatorcontrib><description>Summary
The post-operative incidence of venous thromboembolism (VTE) is high for patients undergoing hip fracture surgery. Proven prophylactic measures are available although underutilized due to concern on post-operative bleeding with use of anticoagulants. This study retrospectively reviewed the clinical incidence of VTE and utilisation of thromboprophylactic protocols over an eight year period. Demographic details, mechanism of injury, VTE risk factors, prophylactic modalities (mechanical and pharmacological), operation duration, mode of anaesthesia, hospital length of stay (LOS) and post-operative complications with particular attention to suspected deep vein thrombosis (DVT) and/or pulmonary embolism (PE) were analysed. Male to female ratio was 1: 2.7 with a median age of 78 years (IQR: 70–86 years) and 83 years (IQR: 77–87 years) respectively (p<0.001). Median hospital LOS was 8 days (IQR: 5–13 days) and differed with mechanism of injury. The in-hospital incidence of VTE was 1.6% (95% CI:1.1–2.5%) with a probably underestimated three month rate of 8.2% (95% CI:5.3–12.4%). Non fatal PE was 0.5% (95% CI: 0.2–1.0%) in-hospital and 2.6% (95% CI: 1.2–5.5%) at three months. Fatal PE was 0.5% (95% CI: 0.2–1.0%) with a three month incidence of 0.4% (95% CI: 0.1–2.4%). The in-hospitalVTE incidence was kept relatively low with use of prophylactic protocols with almost all patients receiving prophylaxis by the end of the study period. Given the five-fold out of hospital increase in incidence, consideration should be given to continue prophylaxis beyond hospital discharge in this high risk group of patients.</description><identifier>ISSN: 0340-6245</identifier><identifier>EISSN: 2567-689X</identifier><identifier>DOI: 10.1160/TH04-10-0696</identifier><identifier>PMID: 16363242</identifier><identifier>CODEN: THHADQ</identifier><language>eng</language><publisher>Stuttgart: Schattauer Verlag für Medizin und Naturwissenschaften</publisher><subject>Aged ; Aged, 80 and over ; Anesthesia ; Anticoagulants - therapeutic use ; Aspirin - therapeutic use ; Biological and medical sciences ; Blood Coagulation Fibrinoylsis and Cellular Haemostasis ; Blood coagulation. Blood cells ; Blood Loss, Surgical ; Blood Transfusion ; Female ; Femoral Neck Fractures - epidemiology ; Femoral Neck Fractures - surgery ; Fundamental and applied biological sciences. Psychology ; Hematologic and hematopoietic diseases ; Heparin, Low-Molecular-Weight - therapeutic use ; Humans ; Incidence ; Male ; Medical sciences ; Molecular and cellular biology ; Patient Readmission ; Platelet Aggregation Inhibitors - therapeutic use ; Platelet diseases and coagulopathies ; Postoperative Complications - epidemiology ; Postoperative Complications - prevention & control ; Retrospective Studies ; Sex Distribution ; Ticlopidine - analogs & derivatives ; Ticlopidine - therapeutic use ; Treatment Outcome ; Venous Thrombosis - epidemiology ; Venous Thrombosis - prevention & control</subject><ispartof>Thrombosis and haemostasis, 2005-11, Vol.94 (5), p.991-996</ispartof><rights>2006 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c611t-16c6b8c609c29c25707c45a4eeb383671ee74ffb85c69fb618cf155d61ab0d323</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.thieme-connect.de/products/ejournals/pdf/10.1160/TH04-10-0696.pdf$$EPDF$$P50$$Gthieme$$H</linktopdf><linktohtml>$$Uhttps://www.thieme-connect.de/products/ejournals/html/10.1160/TH04-10-0696$$EHTML$$P50$$Gthieme$$H</linktohtml><link.rule.ids>314,780,784,3018,27924,27925,54559,54560</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17270226$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16363242$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hitos, Kerry</creatorcontrib><creatorcontrib>Fletcher, John P.</creatorcontrib><title>Venous thromboembolism and fractured neck of femur</title><title>Thrombosis and haemostasis</title><addtitle>Thromb Haemost</addtitle><description>Summary
The post-operative incidence of venous thromboembolism (VTE) is high for patients undergoing hip fracture surgery. Proven prophylactic measures are available although underutilized due to concern on post-operative bleeding with use of anticoagulants. This study retrospectively reviewed the clinical incidence of VTE and utilisation of thromboprophylactic protocols over an eight year period. Demographic details, mechanism of injury, VTE risk factors, prophylactic modalities (mechanical and pharmacological), operation duration, mode of anaesthesia, hospital length of stay (LOS) and post-operative complications with particular attention to suspected deep vein thrombosis (DVT) and/or pulmonary embolism (PE) were analysed. Male to female ratio was 1: 2.7 with a median age of 78 years (IQR: 70–86 years) and 83 years (IQR: 77–87 years) respectively (p<0.001). Median hospital LOS was 8 days (IQR: 5–13 days) and differed with mechanism of injury. The in-hospital incidence of VTE was 1.6% (95% CI:1.1–2.5%) with a probably underestimated three month rate of 8.2% (95% CI:5.3–12.4%). Non fatal PE was 0.5% (95% CI: 0.2–1.0%) in-hospital and 2.6% (95% CI: 1.2–5.5%) at three months. Fatal PE was 0.5% (95% CI: 0.2–1.0%) with a three month incidence of 0.4% (95% CI: 0.1–2.4%). The in-hospitalVTE incidence was kept relatively low with use of prophylactic protocols with almost all patients receiving prophylaxis by the end of the study period. Given the five-fold out of hospital increase in incidence, consideration should be given to continue prophylaxis beyond hospital discharge in this high risk group of patients.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Anesthesia</subject><subject>Anticoagulants - therapeutic use</subject><subject>Aspirin - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Blood Coagulation Fibrinoylsis and Cellular Haemostasis</subject><subject>Blood coagulation. Blood cells</subject><subject>Blood Loss, Surgical</subject><subject>Blood Transfusion</subject><subject>Female</subject><subject>Femoral Neck Fractures - epidemiology</subject><subject>Femoral Neck Fractures - surgery</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Heparin, Low-Molecular-Weight - therapeutic use</subject><subject>Humans</subject><subject>Incidence</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Molecular and cellular biology</subject><subject>Patient Readmission</subject><subject>Platelet Aggregation Inhibitors - therapeutic use</subject><subject>Platelet diseases and coagulopathies</subject><subject>Postoperative Complications - epidemiology</subject><subject>Postoperative Complications - prevention & control</subject><subject>Retrospective Studies</subject><subject>Sex Distribution</subject><subject>Ticlopidine - analogs & derivatives</subject><subject>Ticlopidine - therapeutic use</subject><subject>Treatment Outcome</subject><subject>Venous Thrombosis - epidemiology</subject><subject>Venous Thrombosis - prevention & control</subject><issn>0340-6245</issn><issn>2567-689X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqtkEGL1TAURoMozpvRnWvpRjdaTdI0bZcy6Iww4GYUdyG9vaUZm-aZmyr-e1NecUBwJySESw7flxzGngn-RgjN395ec1UKXnLd6QfsIGvdlLrtvj5kB14pXmqp6jN2TnTHudCqqx-zM6ErXUklD0x-wSWsVKQpBt8HzHt25Au7DMUYLaQ14lAsCN-KMBYj-jU-YY9GOxM-3c8L9vnD-9vL6_Lm09XHy3c3JWghUik06L4FzTuQedUNb0DVViH2VVvpRiA2ahz7tgbdjb0WLYyirgctbM-HSlYX7OUp9xjD9xUpGe8IcJ7tgvnJJn-St7VQGXx9AiEGooijOUbnbfxlBDebI7M52obNUcaf77lr73G4h3cpGXixA5bAzlnDAo7uuUY2XMot6NWJS5NDj-YurHHJRv5VCyeaYLIp2RXjn8jdPuWWLN5MFn2gZLcZwpJwSfkiwuR-oHFEKxo6Ijg7G2-XlSC6YzKq4jy3uP_Y0jT87wZDU_hppuTn6jdGyMw1</recordid><startdate>20051101</startdate><enddate>20051101</enddate><creator>Hitos, Kerry</creator><creator>Fletcher, John P.</creator><general>Schattauer Verlag für Medizin und Naturwissenschaften</general><general>Schattauer GmbH</general><general>Schattauer</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20051101</creationdate><title>Venous thromboembolism and fractured neck of femur</title><author>Hitos, Kerry ; Fletcher, John P.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c611t-16c6b8c609c29c25707c45a4eeb383671ee74ffb85c69fb618cf155d61ab0d323</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Anesthesia</topic><topic>Anticoagulants - therapeutic use</topic><topic>Aspirin - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Blood Coagulation Fibrinoylsis and Cellular Haemostasis</topic><topic>Blood coagulation. Blood cells</topic><topic>Blood Loss, Surgical</topic><topic>Blood Transfusion</topic><topic>Female</topic><topic>Femoral Neck Fractures - epidemiology</topic><topic>Femoral Neck Fractures - surgery</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Hematologic and hematopoietic diseases</topic><topic>Heparin, Low-Molecular-Weight - therapeutic use</topic><topic>Humans</topic><topic>Incidence</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Molecular and cellular biology</topic><topic>Patient Readmission</topic><topic>Platelet Aggregation Inhibitors - therapeutic use</topic><topic>Platelet diseases and coagulopathies</topic><topic>Postoperative Complications - epidemiology</topic><topic>Postoperative Complications - prevention & control</topic><topic>Retrospective Studies</topic><topic>Sex Distribution</topic><topic>Ticlopidine - analogs & derivatives</topic><topic>Ticlopidine - therapeutic use</topic><topic>Treatment Outcome</topic><topic>Venous Thrombosis - epidemiology</topic><topic>Venous Thrombosis - prevention & control</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hitos, Kerry</creatorcontrib><creatorcontrib>Fletcher, John P.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Thrombosis and haemostasis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hitos, Kerry</au><au>Fletcher, John P.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Venous thromboembolism and fractured neck of femur</atitle><jtitle>Thrombosis and haemostasis</jtitle><addtitle>Thromb Haemost</addtitle><date>2005-11-01</date><risdate>2005</risdate><volume>94</volume><issue>5</issue><spage>991</spage><epage>996</epage><pages>991-996</pages><issn>0340-6245</issn><eissn>2567-689X</eissn><coden>THHADQ</coden><abstract>Summary
The post-operative incidence of venous thromboembolism (VTE) is high for patients undergoing hip fracture surgery. Proven prophylactic measures are available although underutilized due to concern on post-operative bleeding with use of anticoagulants. This study retrospectively reviewed the clinical incidence of VTE and utilisation of thromboprophylactic protocols over an eight year period. Demographic details, mechanism of injury, VTE risk factors, prophylactic modalities (mechanical and pharmacological), operation duration, mode of anaesthesia, hospital length of stay (LOS) and post-operative complications with particular attention to suspected deep vein thrombosis (DVT) and/or pulmonary embolism (PE) were analysed. Male to female ratio was 1: 2.7 with a median age of 78 years (IQR: 70–86 years) and 83 years (IQR: 77–87 years) respectively (p<0.001). Median hospital LOS was 8 days (IQR: 5–13 days) and differed with mechanism of injury. The in-hospital incidence of VTE was 1.6% (95% CI:1.1–2.5%) with a probably underestimated three month rate of 8.2% (95% CI:5.3–12.4%). Non fatal PE was 0.5% (95% CI: 0.2–1.0%) in-hospital and 2.6% (95% CI: 1.2–5.5%) at three months. Fatal PE was 0.5% (95% CI: 0.2–1.0%) with a three month incidence of 0.4% (95% CI: 0.1–2.4%). The in-hospitalVTE incidence was kept relatively low with use of prophylactic protocols with almost all patients receiving prophylaxis by the end of the study period. Given the five-fold out of hospital increase in incidence, consideration should be given to continue prophylaxis beyond hospital discharge in this high risk group of patients.</abstract><cop>Stuttgart</cop><pub>Schattauer Verlag für Medizin und Naturwissenschaften</pub><pmid>16363242</pmid><doi>10.1160/TH04-10-0696</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0340-6245 |
| ispartof | Thrombosis and haemostasis, 2005-11, Vol.94 (5), p.991-996 |
| issn | 0340-6245 2567-689X |
| language | eng |
| recordid | cdi_pubmed_primary_16363242 |
| source | MEDLINE; Thieme Connect Journals |
| subjects | Aged Aged, 80 and over Anesthesia Anticoagulants - therapeutic use Aspirin - therapeutic use Biological and medical sciences Blood Coagulation Fibrinoylsis and Cellular Haemostasis Blood coagulation. Blood cells Blood Loss, Surgical Blood Transfusion Female Femoral Neck Fractures - epidemiology Femoral Neck Fractures - surgery Fundamental and applied biological sciences. Psychology Hematologic and hematopoietic diseases Heparin, Low-Molecular-Weight - therapeutic use Humans Incidence Male Medical sciences Molecular and cellular biology Patient Readmission Platelet Aggregation Inhibitors - therapeutic use Platelet diseases and coagulopathies Postoperative Complications - epidemiology Postoperative Complications - prevention & control Retrospective Studies Sex Distribution Ticlopidine - analogs & derivatives Ticlopidine - therapeutic use Treatment Outcome Venous Thrombosis - epidemiology Venous Thrombosis - prevention & control |
| title | Venous thromboembolism and fractured neck of femur |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T14%3A12%3A34IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Venous%20thromboembolism%20and%20fractured%20neck%20of%20femur&rft.jtitle=Thrombosis%20and%20haemostasis&rft.au=Hitos,%20Kerry&rft.date=2005-11-01&rft.volume=94&rft.issue=5&rft.spage=991&rft.epage=996&rft.pages=991-996&rft.issn=0340-6245&rft.eissn=2567-689X&rft.coden=THHADQ&rft_id=info:doi/10.1160/TH04-10-0696&rft_dat=%3Cproquest_pubme%3E68908514%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=68908514&rft_id=info:pmid/16363242&rfr_iscdi=true |