Cigarette smoke disrupts VEGF165-VEGFR-2 receptor signaling complex in rat lungs and patients with COPD: morphological impact of VEGFR-2 inhibition

1 Novartis Institute for Biomedical Research, Horsham, and 2 Respiratory Medicine Unit, Medical Research Council Centre for Inflammation Research, University of Edinburgh, Edinburgh, United Kingdom; and 3 Department of Environmental Medicine, Lung Biology and Disease Program, University of Rochester...

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Veröffentlicht in:	American journal of physiology. Lung cellular and molecular physiology 2006-05, Vol.290 (5), p.L897-L908
Hauptverfasser:	Marwick, John A, Stevenson, Christopher S, Giddings, June, MacNee, William, Butler, Keith, Rahman, Irfan, Kirkham, Paul A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Forced Expiratory Volume Humans Lung - pathology Lung - physiopathology Male Pulmonary Disease, Chronic Obstructive - physiopathology Rats Rats, Sprague-Dawley Signal Transduction - drug effects Smoke - adverse effects Smoking - physiopathology Vascular Endothelial Growth Factor A - drug effects Vascular Endothelial Growth Factor A - genetics Vascular Endothelial Growth Factor A - physiology Vascular Endothelial Growth Factor Receptor-2 - drug effects Vascular Endothelial Growth Factor Receptor-2 - physiology
Online-Zugang:	Volltext
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