Mitomycin C and Capecitabine Combination (MiXe) in Heavily Pretreated Metastatic Breast Cancer Patients. A Dose-finding Study

Background: No standard chemotherapy has been defined for metastatic breast cancer patients pretreated with anthracyclines and taxanes. In preclinical studies, mitomycin C (MMC) and capecitabine showed a synergistic effect by up-regulation of thymidine phosphorylase, and both drugs were active again...

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Veröffentlicht in:	Anticancer research 2005-11, Vol.25 (6C), p.4513-4517
Hauptverfasser:	MAISANO, Roberto, CARISTI, Nicola, MARE, Marzia, MAFODDA, Antonino, CARBONI, Rita, MONTALTO, Erika, IORFIDA, Monica, NARDI, Mario
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antineoplastic Combined Chemotherapy Protocols - administration & dosage Antineoplastic Combined Chemotherapy Protocols - adverse effects Biological and medical sciences Breast Neoplasms - drug therapy Breast Neoplasms - pathology Capecitabine Deoxycytidine - administration & dosage Deoxycytidine - adverse effects Deoxycytidine - analogs & derivatives Dose-Response Relationship, Drug Drug Administration Schedule Female Fluorouracil - analogs & derivatives Gynecology. Andrology. Obstetrics Humans Mammary gland diseases Medical sciences Middle Aged Mitomycin - administration & dosage Mitomycin - adverse effects Neoplasm Metastasis Tumors
Online-Zugang:	Volltext
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