Proteinuria and Fusion of Podocyte Foot Processes in Rats after Infusion of Cytokine from Patients with Idiopathic Minimal Lesion Nephrotic Syndrome

Background/Aims: We report on the isolation of a factor secreted by peripheral blood mononuclear cells from patients with idiopathic minimal lesion nephrotic syndrome (IMLNS) in relapse and its effect on proteinuria and podocyte morphology in the rat. Methods: Peripheral blood mononuclear cells from...

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Veröffentlicht in:	Nephron. Experimental nephrology 2006-01, Vol.102 (3-4), p.e105-e112
Hauptverfasser:	Garin, Eduardo H., Laflam, Paul F., Muffly, Karl
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Animals Apoferritins - administration & dosage Apoferritins - blood beta-Amylase - administration & dosage beta-Amylase - blood Blood Protein Electrophoresis Child Child, Preschool Cytokines - administration & dosage Cytokines - blood Electrophoresis Female Glomerulosclerosis, Focal Segmental - blood Glycoproteins - blood Glycoproteins - chemistry Glycoproteins - pharmacology Humans Hydrogen-Ion Concentration Infusion Pumps Kidney - pathology Male Molecular Weight Nephrotic Syndrome - blood Original Paper Podocytes - pathology Proteinuria - etiology Rats Rats, Sprague-Dawley Recurrence Serum Albumin, Bovine - administration & dosage Serum Albumin, Bovine - pharmacology
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