Two acylated flavonoid glycosides from Stachys bombycina, and their free radical scavenging activity
Preparative reversed-phase HPLC analysis of the methanol extract of the aerial parts of Stachys bombycina (Lamiaceae) afforded two acylated flavonoids glycosides, chrysoeriol 7-O-[6-O-acetyl-β-D-allopyranosyl]-(1 → 2)-β-D-glucopyranoside (1) and apigenin 7-O-β-D-(6-p-coumaroyl)-glucopyranoside (2),...
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| Veröffentlicht in: | Pharmazie 2005-11, Vol.60 (11), p.878-880 |
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| creator | Delazar, A. Celik, S. Göktürk, R. S. Unal, O. Nahar, L. Sarker, S. D. |
| description | Preparative reversed-phase HPLC analysis of the methanol extract of the aerial parts of Stachys bombycina (Lamiaceae) afforded two acylated flavonoids glycosides, chrysoeriol 7-O-[6-O-acetyl-β-D-allopyranosyl]-(1 → 2)-β-D-glucopyranoside (1)
and apigenin 7-O-β-D-(6-p-coumaroyl)-glucopyranoside (2), the former being a new natural product. The structures of these compounds were elucidated unambiguously by UV spectroscopic analyses using shift reagents, ESIMS, and 1D and 2D NMR spectroscopic techniques.
The free radical scavenging activity of 1 and 2 compounds were assessed by DPPH assay, and the RC50 values were 1.25 × 10-2 and 7.69 × 10-4 mg/mL, respectively. |
| format | Article |
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and apigenin 7-O-β-D-(6-p-coumaroyl)-glucopyranoside (2), the former being a new natural product. The structures of these compounds were elucidated unambiguously by UV spectroscopic analyses using shift reagents, ESIMS, and 1D and 2D NMR spectroscopic techniques.
The free radical scavenging activity of 1 and 2 compounds were assessed by DPPH assay, and the RC50 values were 1.25 × 10-2 and 7.69 × 10-4 mg/mL, respectively.</description><identifier>ISSN: 0031-7144</identifier><identifier>PMID: 16320954</identifier><language>eng</language><publisher>Germany: Govi-Verlag</publisher><subject>Acylation ; Apigenin - chemistry ; Area Under Curve ; Chromatography, High Pressure Liquid ; Flavones ; Flavonoids - chemistry ; Flavonoids - pharmacology ; Free Radical Scavengers ; Glycosides - chemistry ; Magnetic Resonance Spectroscopy ; Plant Extracts - chemistry ; Plant Extracts - pharmacology ; Spectrometry, Mass, Electrospray Ionization ; Stachys - chemistry</subject><ispartof>Pharmazie, 2005-11, Vol.60 (11), p.878-880</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>288,314,776,780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16320954$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Delazar, A.</creatorcontrib><creatorcontrib>Celik, S.</creatorcontrib><creatorcontrib>Göktürk, R. S.</creatorcontrib><creatorcontrib>Unal, O.</creatorcontrib><creatorcontrib>Nahar, L.</creatorcontrib><creatorcontrib>Sarker, S. D.</creatorcontrib><title>Two acylated flavonoid glycosides from Stachys bombycina, and their free radical scavenging activity</title><title>Pharmazie</title><addtitle>Pharmazie</addtitle><description>Preparative reversed-phase HPLC analysis of the methanol extract of the aerial parts of Stachys bombycina (Lamiaceae) afforded two acylated flavonoids glycosides, chrysoeriol 7-O-[6-O-acetyl-β-D-allopyranosyl]-(1 → 2)-β-D-glucopyranoside (1)
and apigenin 7-O-β-D-(6-p-coumaroyl)-glucopyranoside (2), the former being a new natural product. The structures of these compounds were elucidated unambiguously by UV spectroscopic analyses using shift reagents, ESIMS, and 1D and 2D NMR spectroscopic techniques.
The free radical scavenging activity of 1 and 2 compounds were assessed by DPPH assay, and the RC50 values were 1.25 × 10-2 and 7.69 × 10-4 mg/mL, respectively.</description><subject>Acylation</subject><subject>Apigenin - chemistry</subject><subject>Area Under Curve</subject><subject>Chromatography, High Pressure Liquid</subject><subject>Flavones</subject><subject>Flavonoids - chemistry</subject><subject>Flavonoids - pharmacology</subject><subject>Free Radical Scavengers</subject><subject>Glycosides - chemistry</subject><subject>Magnetic Resonance Spectroscopy</subject><subject>Plant Extracts - chemistry</subject><subject>Plant Extracts - pharmacology</subject><subject>Spectrometry, Mass, Electrospray Ionization</subject><subject>Stachys - chemistry</subject><issn>0031-7144</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kE9v2yAYh33otHTZvkLFaadFAoOxOU7ttlaK1ErrzugNfxwiG1LAntxPP9Kkx3HhJ_Hw6H1_V9U1xpRsWsLYqvqU0gHjmte8-1itCKc1Fg27rvTz34BALQNko5EdYA4-OI36YVEhOW0SsjGM6HcGtV8S2oVxtyjn4RsCr1HeGxcLYQyKoJ2CASUFs_G9833xZje7vHyuPlgYkvlyudfVn58_nm_vN9vHXw-337cbRxnNGyGIZhoDaUXXKEsZEZZSaE0rdGOBKA5YtVYJzpih1Npmx8tz01FFNRGErquvZ-8xhpfJpCxHl5QZBvAmTEnyrmtqJlgBby7gtBuNlsfoRoiLfO-lAE9noKxhfAZ5CFP0ZXbplOzD7OSp21O1cubYEyJrXBPcESrL_05qY2EasswQZf8qUxGvq7v_KN98xz3EEV6LBzdFfjocX0LRQ8ynwOk_v-uPkQ</recordid><startdate>20051101</startdate><enddate>20051101</enddate><creator>Delazar, A.</creator><creator>Celik, S.</creator><creator>Göktürk, R. S.</creator><creator>Unal, O.</creator><creator>Nahar, L.</creator><creator>Sarker, S. D.</creator><general>Govi-Verlag</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20051101</creationdate><title>Two acylated flavonoid glycosides from Stachys bombycina, and their free radical scavenging activity</title><author>Delazar, A. ; Celik, S. ; Göktürk, R. S. ; Unal, O. ; Nahar, L. ; Sarker, S. D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-i343t-991d4d0a17985cf3419f33a7e79d5fa1c6a0c7fc9644e33ff5b63a7583c3d1913</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Acylation</topic><topic>Apigenin - chemistry</topic><topic>Area Under Curve</topic><topic>Chromatography, High Pressure Liquid</topic><topic>Flavones</topic><topic>Flavonoids - chemistry</topic><topic>Flavonoids - pharmacology</topic><topic>Free Radical Scavengers</topic><topic>Glycosides - chemistry</topic><topic>Magnetic Resonance Spectroscopy</topic><topic>Plant Extracts - chemistry</topic><topic>Plant Extracts - pharmacology</topic><topic>Spectrometry, Mass, Electrospray Ionization</topic><topic>Stachys - chemistry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Delazar, A.</creatorcontrib><creatorcontrib>Celik, S.</creatorcontrib><creatorcontrib>Göktürk, R. S.</creatorcontrib><creatorcontrib>Unal, O.</creatorcontrib><creatorcontrib>Nahar, L.</creatorcontrib><creatorcontrib>Sarker, S. D.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Pharmazie</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Delazar, A.</au><au>Celik, S.</au><au>Göktürk, R. S.</au><au>Unal, O.</au><au>Nahar, L.</au><au>Sarker, S. D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Two acylated flavonoid glycosides from Stachys bombycina, and their free radical scavenging activity</atitle><jtitle>Pharmazie</jtitle><addtitle>Pharmazie</addtitle><date>2005-11-01</date><risdate>2005</risdate><volume>60</volume><issue>11</issue><spage>878</spage><epage>880</epage><pages>878-880</pages><issn>0031-7144</issn><abstract>Preparative reversed-phase HPLC analysis of the methanol extract of the aerial parts of Stachys bombycina (Lamiaceae) afforded two acylated flavonoids glycosides, chrysoeriol 7-O-[6-O-acetyl-β-D-allopyranosyl]-(1 → 2)-β-D-glucopyranoside (1)
and apigenin 7-O-β-D-(6-p-coumaroyl)-glucopyranoside (2), the former being a new natural product. The structures of these compounds were elucidated unambiguously by UV spectroscopic analyses using shift reagents, ESIMS, and 1D and 2D NMR spectroscopic techniques.
The free radical scavenging activity of 1 and 2 compounds were assessed by DPPH assay, and the RC50 values were 1.25 × 10-2 and 7.69 × 10-4 mg/mL, respectively.</abstract><cop>Germany</cop><pub>Govi-Verlag</pub><pmid>16320954</pmid><tpages>3</tpages></addata></record> |
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| ispartof | Pharmazie, 2005-11, Vol.60 (11), p.878-880 |
| issn | 0031-7144 |
| language | eng |
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| source | MEDLINE; EZB Free E-Journals; IngentaConnect Open Access Journals |
| subjects | Acylation Apigenin - chemistry Area Under Curve Chromatography, High Pressure Liquid Flavones Flavonoids - chemistry Flavonoids - pharmacology Free Radical Scavengers Glycosides - chemistry Magnetic Resonance Spectroscopy Plant Extracts - chemistry Plant Extracts - pharmacology Spectrometry, Mass, Electrospray Ionization Stachys - chemistry |
| title | Two acylated flavonoid glycosides from Stachys bombycina, and their free radical scavenging activity |
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