Treating dry skin and pruritus with a bath oil containing soya oil and lauromacrogols
ABSTRACT The efficacy and safety of a bath oil containing soya oil and anti-pruritic lauromacrogols* have been demonstrated in experimental and clinical studies. In order to generate more efficacy and safety-related data on the day-to-day use in paediatric practice, a post-marketing surveillance stu...
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Veröffentlicht in: | Current medical research and opinion 2005-11, Vol.21 (11), p.1735-1739 |
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description | ABSTRACT
The efficacy and safety of a bath oil containing soya oil and anti-pruritic lauromacrogols* have been demonstrated in experimental and clinical studies. In order to generate more efficacy and safety-related data on the day-to-day use in paediatric practice, a post-marketing surveillance study has been conducted. More than 3500 patients – the vast majority (61.4%) aged 0–4 years – were included in this investigation. Atopic eczema was diagnosed in 86.4% of the cases. The average duration of treatment was 42 days.
*Balneum Plus bath oil, Hermal
The results confirm that the anti-pruritic bath oil is both well-tolerated and effective in treating dry and itchy skin diseases. The sum score of symptoms decreased during the treatment of symptoms decreased during the treatment period from 7.21 to 2.71 mean score points. The physicians assessed the global efficacy in 89.4% of the cases as ‘very good’ or ‘good’. Anti-pruritic properties of the combination were rated ‘very good’ or ‘good’ in 84.3%. The local tolerability was stated to be ‘good’ or ‘very good’ in 96.8% of the patients. In total, only 10 out of the 3566 patients, 0.28% respectively, experienced discomfort.
Moreover, the physicians estimated that the bath oil therapy helped to reduce therapeutics like steroids in nearly 60% of patients. The potential to reduce use of external steroids and other specific therapeutics is also of particular relevance from a pharmacoeconomic point of view. |
doi_str_mv | 10.1185/030079905X62963 |
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The efficacy and safety of a bath oil containing soya oil and anti-pruritic lauromacrogols* have been demonstrated in experimental and clinical studies. In order to generate more efficacy and safety-related data on the day-to-day use in paediatric practice, a post-marketing surveillance study has been conducted. More than 3500 patients – the vast majority (61.4%) aged 0–4 years – were included in this investigation. Atopic eczema was diagnosed in 86.4% of the cases. The average duration of treatment was 42 days.
*Balneum Plus bath oil, Hermal
The results confirm that the anti-pruritic bath oil is both well-tolerated and effective in treating dry and itchy skin diseases. The sum score of symptoms decreased during the treatment of symptoms decreased during the treatment period from 7.21 to 2.71 mean score points. The physicians assessed the global efficacy in 89.4% of the cases as ‘very good’ or ‘good’. Anti-pruritic properties of the combination were rated ‘very good’ or ‘good’ in 84.3%. The local tolerability was stated to be ‘good’ or ‘very good’ in 96.8% of the patients. In total, only 10 out of the 3566 patients, 0.28% respectively, experienced discomfort.
Moreover, the physicians estimated that the bath oil therapy helped to reduce therapeutics like steroids in nearly 60% of patients. The potential to reduce use of external steroids and other specific therapeutics is also of particular relevance from a pharmacoeconomic point of view.</description><identifier>ISSN: 0300-7995</identifier><identifier>EISSN: 1473-4877</identifier><identifier>DOI: 10.1185/030079905X62963</identifier><identifier>PMID: 16307693</identifier><identifier>CODEN: CMROCX</identifier><language>eng</language><publisher>England: Informa UK Ltd</publisher><subject>Adolescent ; Adult ; Antipruritics - therapeutic use ; Baths ; Child ; Child, Preschool ; Dermatologic Agents - therapeutic use ; Dry skin ; Emollients - therapeutic use ; Humans ; Infant ; Lauromacrogols ; Polyethylene Glycols - chemistry ; Polyethylene Glycols - therapeutic use ; Product Surveillance, Postmarketing ; Pruritus ; Pruritus - therapy ; Skin Diseases - pathology ; Skin Diseases - therapy ; Soya oil ; Soybean Oil - therapeutic use ; Treatment Outcome</subject><ispartof>Current medical research and opinion, 2005-11, Vol.21 (11), p.1735-1739</ispartof><rights>2005 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 2005</rights><rights>Copyright Librapharm Nov 2005</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c423t-4a111e2d23897120f1f541c49ec68067bcf829ca56f99db1abc119f89974231f3</citedby><cites>FETCH-LOGICAL-c423t-4a111e2d23897120f1f541c49ec68067bcf829ca56f99db1abc119f89974231f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.1185/030079905X62963$$EPDF$$P50$$Ginformahealthcare$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.1185/030079905X62963$$EHTML$$P50$$Ginformahealthcare$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,59620,59726,60409,60515,61194,61229,61375,61410</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16307693$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bettzuege-Pfaff, Barbara I.</creatorcontrib><creatorcontrib>Melzer, Antje</creatorcontrib><title>Treating dry skin and pruritus with a bath oil containing soya oil and lauromacrogols</title><title>Current medical research and opinion</title><addtitle>Curr Med Res Opin</addtitle><description>ABSTRACT
The efficacy and safety of a bath oil containing soya oil and anti-pruritic lauromacrogols* have been demonstrated in experimental and clinical studies. In order to generate more efficacy and safety-related data on the day-to-day use in paediatric practice, a post-marketing surveillance study has been conducted. More than 3500 patients – the vast majority (61.4%) aged 0–4 years – were included in this investigation. Atopic eczema was diagnosed in 86.4% of the cases. The average duration of treatment was 42 days.
*Balneum Plus bath oil, Hermal
The results confirm that the anti-pruritic bath oil is both well-tolerated and effective in treating dry and itchy skin diseases. The sum score of symptoms decreased during the treatment of symptoms decreased during the treatment period from 7.21 to 2.71 mean score points. The physicians assessed the global efficacy in 89.4% of the cases as ‘very good’ or ‘good’. Anti-pruritic properties of the combination were rated ‘very good’ or ‘good’ in 84.3%. The local tolerability was stated to be ‘good’ or ‘very good’ in 96.8% of the patients. In total, only 10 out of the 3566 patients, 0.28% respectively, experienced discomfort.
Moreover, the physicians estimated that the bath oil therapy helped to reduce therapeutics like steroids in nearly 60% of patients. The potential to reduce use of external steroids and other specific therapeutics is also of particular relevance from a pharmacoeconomic point of view.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Antipruritics - therapeutic use</subject><subject>Baths</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Dermatologic Agents - therapeutic use</subject><subject>Dry skin</subject><subject>Emollients - therapeutic use</subject><subject>Humans</subject><subject>Infant</subject><subject>Lauromacrogols</subject><subject>Polyethylene Glycols - chemistry</subject><subject>Polyethylene Glycols - therapeutic use</subject><subject>Product Surveillance, Postmarketing</subject><subject>Pruritus</subject><subject>Pruritus - therapy</subject><subject>Skin Diseases - pathology</subject><subject>Skin Diseases - therapy</subject><subject>Soya oil</subject><subject>Soybean Oil - therapeutic use</subject><subject>Treatment Outcome</subject><issn>0300-7995</issn><issn>1473-4877</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kE1r3DAQhkVpaLZpz70V00NvbvRh66O3Epq2EMglgd7EWJaySmVpK9mE_feVswuhgZwGZp7nZWYQ-kDwF0Jkf44ZxkIp3P_mVHH2Cm1IJ1jbSSFeo806beu4P0VvS7nHmFCp1Bt0SjjDgiu2Qbc32cLs410z5n1T_vjYQBybXV6yn5fSPPh520AzQC3Jh8akOIOPq1DSHh57qxBgyWkCk9NdCuUdOnEQin1_rGfo9vL7zcXP9ur6x6-Lb1et6Sib2w4IIZaOlEklCMWOuL4jplPWcIm5GIyTVBnouVNqHAgMhhDl6g2i-sSxM_T5kLvL6e9iy6wnX4wNAaJNS9FcSiYEJxX89Ay8T0uOdTdNscSY9nSFzg9QvaKUbJ3eZT9B3muC9fpu_ezd1fh4jF2GyY5P_PG_Ffh6AHx0KU_wkHIY9Qz7kLLLEI0vmr2crv6TtxbCvDWQ7dP2L7n_AMTQnn8</recordid><startdate>200511</startdate><enddate>200511</enddate><creator>Bettzuege-Pfaff, Barbara I.</creator><creator>Melzer, Antje</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><general>Informa Healthcare</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>S0X</scope><scope>7X8</scope></search><sort><creationdate>200511</creationdate><title>Treating dry skin and pruritus with a bath oil containing soya oil and lauromacrogols</title><author>Bettzuege-Pfaff, Barbara I. ; Melzer, Antje</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c423t-4a111e2d23897120f1f541c49ec68067bcf829ca56f99db1abc119f89974231f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Antipruritics - therapeutic use</topic><topic>Baths</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Dermatologic Agents - therapeutic use</topic><topic>Dry skin</topic><topic>Emollients - therapeutic use</topic><topic>Humans</topic><topic>Infant</topic><topic>Lauromacrogols</topic><topic>Polyethylene Glycols - chemistry</topic><topic>Polyethylene Glycols - therapeutic use</topic><topic>Product Surveillance, Postmarketing</topic><topic>Pruritus</topic><topic>Pruritus - therapy</topic><topic>Skin Diseases - pathology</topic><topic>Skin Diseases - therapy</topic><topic>Soya oil</topic><topic>Soybean Oil - therapeutic use</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bettzuege-Pfaff, Barbara I.</creatorcontrib><creatorcontrib>Melzer, Antje</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>SIRS Editorial</collection><collection>MEDLINE - Academic</collection><jtitle>Current medical research and opinion</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bettzuege-Pfaff, Barbara I.</au><au>Melzer, Antje</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Treating dry skin and pruritus with a bath oil containing soya oil and lauromacrogols</atitle><jtitle>Current medical research and opinion</jtitle><addtitle>Curr Med Res Opin</addtitle><date>2005-11</date><risdate>2005</risdate><volume>21</volume><issue>11</issue><spage>1735</spage><epage>1739</epage><pages>1735-1739</pages><issn>0300-7995</issn><eissn>1473-4877</eissn><coden>CMROCX</coden><abstract>ABSTRACT
The efficacy and safety of a bath oil containing soya oil and anti-pruritic lauromacrogols* have been demonstrated in experimental and clinical studies. In order to generate more efficacy and safety-related data on the day-to-day use in paediatric practice, a post-marketing surveillance study has been conducted. More than 3500 patients – the vast majority (61.4%) aged 0–4 years – were included in this investigation. Atopic eczema was diagnosed in 86.4% of the cases. The average duration of treatment was 42 days.
*Balneum Plus bath oil, Hermal
The results confirm that the anti-pruritic bath oil is both well-tolerated and effective in treating dry and itchy skin diseases. The sum score of symptoms decreased during the treatment of symptoms decreased during the treatment period from 7.21 to 2.71 mean score points. The physicians assessed the global efficacy in 89.4% of the cases as ‘very good’ or ‘good’. Anti-pruritic properties of the combination were rated ‘very good’ or ‘good’ in 84.3%. The local tolerability was stated to be ‘good’ or ‘very good’ in 96.8% of the patients. In total, only 10 out of the 3566 patients, 0.28% respectively, experienced discomfort.
Moreover, the physicians estimated that the bath oil therapy helped to reduce therapeutics like steroids in nearly 60% of patients. The potential to reduce use of external steroids and other specific therapeutics is also of particular relevance from a pharmacoeconomic point of view.</abstract><cop>England</cop><pub>Informa UK Ltd</pub><pmid>16307693</pmid><doi>10.1185/030079905X62963</doi><tpages>5</tpages></addata></record> |
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source | MEDLINE; Taylor & Francis Medical Library - CRKN; Taylor & Francis Journals Complete |
subjects | Adolescent Adult Antipruritics - therapeutic use Baths Child Child, Preschool Dermatologic Agents - therapeutic use Dry skin Emollients - therapeutic use Humans Infant Lauromacrogols Polyethylene Glycols - chemistry Polyethylene Glycols - therapeutic use Product Surveillance, Postmarketing Pruritus Pruritus - therapy Skin Diseases - pathology Skin Diseases - therapy Soya oil Soybean Oil - therapeutic use Treatment Outcome |
title | Treating dry skin and pruritus with a bath oil containing soya oil and lauromacrogols |
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