Unique Ligand Binding Sites on CXCR4 Probed by a Chemical Biology Approach: Implications for the Design of Selective Human Immunodeficiency Virus Type 1 Inhibitors
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| Veröffentlicht in: | Journal of Virology 2005-12, Vol.79 (24), p.15398-15404 |
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| container_issue | 24 |
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| container_title | Journal of Virology |
| container_volume | 79 |
| creator | Choi, Won-Tak Tian, Shaomin Dong, Chang-Zhi Kumar, Santosh Liu, Dongxiang Madani, Navid An, Jing Sodroski, Joseph G Huang, Ziwei |
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| doi_str_mv | 10.1128/JVI.79.24.15398-15404.2005 |
| format | Article |
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</description><identifier>ISSN: 0022-538X</identifier><identifier>EISSN: 1098-5514</identifier><identifier>DOI: 10.1128/JVI.79.24.15398-15404.2005</identifier><identifier>PMID: 16306611</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>Anti-HIV Agents - pharmacology ; Binding Sites ; Biological and medical sciences ; Cell Line ; Chemokine CXCL12 ; Chemokines, CXC - chemistry ; Chemokines, CXC - pharmacology ; Fundamental and applied biological sciences. Psychology ; HIV-1 - drug effects ; HIV-1 - physiology ; Human immunodeficiency virus 1 ; Human viral diseases ; Humans ; Infectious diseases ; Ligands ; Medical sciences ; Microbiology ; Miscellaneous ; Protein Binding ; Receptors, CXCR4 - metabolism ; Stromal Cells ; Vaccines and Antiviral Agents ; Viral diseases ; Viral diseases of the lymphoid tissue and the blood. Aids ; Virology ; Virus Replication - drug effects</subject><ispartof>Journal of Virology, 2005-12, Vol.79 (24), p.15398-15404</ispartof><rights>2006 INIST-CNRS</rights><rights>Copyright © 2005, American Society for Microbiology 2005</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c579t-80cba67a52642c1576eb337cc171092e3bc76c2b07c8c225efa9bd2ea122199c3</citedby><cites>FETCH-LOGICAL-c579t-80cba67a52642c1576eb337cc171092e3bc76c2b07c8c225efa9bd2ea122199c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1316031/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1316031/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,727,780,784,885,27923,27924,53790,53792</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17320719$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16306611$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Choi, Won-Tak</creatorcontrib><creatorcontrib>Tian, Shaomin</creatorcontrib><creatorcontrib>Dong, Chang-Zhi</creatorcontrib><creatorcontrib>Kumar, Santosh</creatorcontrib><creatorcontrib>Liu, Dongxiang</creatorcontrib><creatorcontrib>Madani, Navid</creatorcontrib><creatorcontrib>An, Jing</creatorcontrib><creatorcontrib>Sodroski, Joseph G</creatorcontrib><creatorcontrib>Huang, Ziwei</creatorcontrib><title>Unique Ligand Binding Sites on CXCR4 Probed by a Chemical Biology Approach: Implications for the Design of Selective Human Immunodeficiency Virus Type 1 Inhibitors</title><title>Journal of Virology</title><addtitle>J Virol</addtitle><description>Article Usage Stats
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</description><subject>Anti-HIV Agents - pharmacology</subject><subject>Binding Sites</subject><subject>Biological and medical sciences</subject><subject>Cell Line</subject><subject>Chemokine CXCL12</subject><subject>Chemokines, CXC - chemistry</subject><subject>Chemokines, CXC - pharmacology</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>HIV-1 - drug effects</subject><subject>HIV-1 - physiology</subject><subject>Human immunodeficiency virus 1</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>Ligands</subject><subject>Medical sciences</subject><subject>Microbiology</subject><subject>Miscellaneous</subject><subject>Protein Binding</subject><subject>Receptors, CXCR4 - metabolism</subject><subject>Stromal Cells</subject><subject>Vaccines and Antiviral Agents</subject><subject>Viral diseases</subject><subject>Viral diseases of the lymphoid tissue and the blood. Aids</subject><subject>Virology</subject><subject>Virus Replication - drug effects</subject><issn>0022-538X</issn><issn>1098-5514</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkttu1DAQhiMEotuFV0AWiN7t4kNiJ71AKsuhi1YC0YN6ZznOJHGV2MFOFu3z8KK43RUtV1yN5Pnmn_HMnySvCV4SQvN3X6_XS1EsabokGSvyBclSnC4pxtmTZEZwfMkykj5NZhhTushYfnOUHIdwizFJU54-T44IZ5hzQmbJ7ytrfk6ANqZRtkIfjK2MbdCFGSEgZ9HqZvUjRd-9K6FC5Q4ptGqhN1p1kXWda3bobBi8U7o9Ret-6GJqNM4GVDuPxhbQRwimscjV6AI60KPZAjqfemUj3k_WVVAbbcDqHbo2fgrocjcAImhtW1Oa0fnwInlWqy7Ay0OcJ1efP12uzhebb1_Wq7PNQmeiGBc51qXiQmWUp1STTHAoGRNaExGXQoGVWnBNSyx0rinNoFZFWVFQhFJSFJrNk_d73WEqe6g02NGrTg7e9MrvpFNG_puxppWN20rCCMeMRIGTg4B3calhlL0JGrpOWXBTkDzPqUhF9l-QFExwTHkET_eg9i4ED_XfaQiWd2aQ0QxSFJKm8t4M8t4M8s4MsfjV4_88lB6uH4G3B0CFeNHaK6tNeOAEo1jEWebJmz3Xmqb9ZTxIFXp5uzWPO7M_9HnLng</recordid><startdate>20051201</startdate><enddate>20051201</enddate><creator>Choi, Won-Tak</creator><creator>Tian, Shaomin</creator><creator>Dong, Chang-Zhi</creator><creator>Kumar, Santosh</creator><creator>Liu, Dongxiang</creator><creator>Madani, Navid</creator><creator>An, Jing</creator><creator>Sodroski, Joseph G</creator><creator>Huang, Ziwei</creator><general>American Society for Microbiology</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>7U9</scope><scope>8FD</scope><scope>FR3</scope><scope>H94</scope><scope>P64</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20051201</creationdate><title>Unique Ligand Binding Sites on CXCR4 Probed by a Chemical Biology Approach: Implications for the Design of Selective Human Immunodeficiency Virus Type 1 Inhibitors</title><author>Choi, Won-Tak ; Tian, Shaomin ; Dong, Chang-Zhi ; Kumar, Santosh ; Liu, Dongxiang ; Madani, Navid ; An, Jing ; Sodroski, Joseph G ; Huang, Ziwei</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c579t-80cba67a52642c1576eb337cc171092e3bc76c2b07c8c225efa9bd2ea122199c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Anti-HIV Agents - pharmacology</topic><topic>Binding Sites</topic><topic>Biological and medical sciences</topic><topic>Cell Line</topic><topic>Chemokine CXCL12</topic><topic>Chemokines, CXC - chemistry</topic><topic>Chemokines, CXC - pharmacology</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>HIV-1 - drug effects</topic><topic>HIV-1 - physiology</topic><topic>Human immunodeficiency virus 1</topic><topic>Human viral diseases</topic><topic>Humans</topic><topic>Infectious diseases</topic><topic>Ligands</topic><topic>Medical sciences</topic><topic>Microbiology</topic><topic>Miscellaneous</topic><topic>Protein Binding</topic><topic>Receptors, CXCR4 - metabolism</topic><topic>Stromal Cells</topic><topic>Vaccines and Antiviral Agents</topic><topic>Viral diseases</topic><topic>Viral diseases of the lymphoid tissue and the blood. 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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>16306611</pmid><doi>10.1128/JVI.79.24.15398-15404.2005</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-538X |
| ispartof | Journal of Virology, 2005-12, Vol.79 (24), p.15398-15404 |
| issn | 0022-538X 1098-5514 |
| language | eng |
| recordid | cdi_pubmed_primary_16306611 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; PubMed Central |
| subjects | Anti-HIV Agents - pharmacology Binding Sites Biological and medical sciences Cell Line Chemokine CXCL12 Chemokines, CXC - chemistry Chemokines, CXC - pharmacology Fundamental and applied biological sciences. Psychology HIV-1 - drug effects HIV-1 - physiology Human immunodeficiency virus 1 Human viral diseases Humans Infectious diseases Ligands Medical sciences Microbiology Miscellaneous Protein Binding Receptors, CXCR4 - metabolism Stromal Cells Vaccines and Antiviral Agents Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Virology Virus Replication - drug effects |
| title | Unique Ligand Binding Sites on CXCR4 Probed by a Chemical Biology Approach: Implications for the Design of Selective Human Immunodeficiency Virus Type 1 Inhibitors |
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