Effects of polyphyllin D, a steroidal saponin in Paris Polyphylla, in growth inhibition of human breast cancer cells and in xenograft

Paris Polyphylla is a traditional Chinese Medical herb that has been used in treating cancer for thousands of year. Without studies on the anticancer effects of Paris Polyphylla being initiated before, we have first studied the component of Paris Polyphylla and have spotted out a steroidal saponin,...

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Veröffentlicht in:	Cancer biology & therapy 2005-11, Vol.4 (11), p.1248-1254
Hauptverfasser:	Lee, Mei-Sze, Chan, Judy Yuet-Wa, Kong, Siu-Kai, Yu, Biao, Eng-Choon, Vincent Ooi, Nai-Ching, Henry Wong, Mak Chung-Wai, Thomas, Fung, Kwok-Pui
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis - drug effects Binding Biology Bioscience Breast Neoplasms - metabolism Breast Neoplasms - pathology Calcium Cancer Cell Cell Line, Tumor Cell Proliferation - drug effects Cell Survival - drug effects Cycle Diosgenin - analogs & derivatives Diosgenin - pharmacology Dose-Response Relationship, Drug Female Humans Inhibitory Concentration 50 Landes Mice Mice, Nude Molecular Structure Neoplasm Transplantation Organogenesis Proteins Saponins - chemistry Saponins - pharmacology Transplantation, Heterologous Xenograft Model Antitumor Assays
Online-Zugang:	Volltext
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