A tumor-like lymphocytis mastitis
A 44-year-old woman presenting with an inflammatory and palpable firm breast lump underwent surgical excision. Intraoperative frozen section analysis showed an extensive lesion consisting of ducts with intraluminal "necrosis". In addition, a very dense stromal inflammation was observed aro...
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Veröffentlicht in: | Annales de pathologie 2005-06, Vol.25 (3), p.231 |
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description | A 44-year-old woman presenting with an inflammatory and palpable firm breast lump underwent surgical excision. Intraoperative frozen section analysis showed an extensive lesion consisting of ducts with intraluminal "necrosis". In addition, a very dense stromal inflammation was observed around these ducts, suggesting an invasive ductal carcinoma with predominant intraductal proliferation. However, on paraffin sections, epithelial cells close to the lymphocytic infiltrate were rare, subatrophic, without any neoplastic feature. The density and architecture of the lymphocytic infiltrate mimicked a breast lymphoma. However, immunochemistry and molecular biology investigation favored the diagnosis of a tumor-like lymphocytic mastitis. Although extremely rare, this particular form of lymphocytic mastitis, a diagnostic pitfall particularly during peroperative examination, should be recognized by pathologists. |
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Intraoperative frozen section analysis showed an extensive lesion consisting of ducts with intraluminal "necrosis". In addition, a very dense stromal inflammation was observed around these ducts, suggesting an invasive ductal carcinoma with predominant intraductal proliferation. However, on paraffin sections, epithelial cells close to the lymphocytic infiltrate were rare, subatrophic, without any neoplastic feature. The density and architecture of the lymphocytic infiltrate mimicked a breast lymphoma. However, immunochemistry and molecular biology investigation favored the diagnosis of a tumor-like lymphocytic mastitis. Although extremely rare, this particular form of lymphocytic mastitis, a diagnostic pitfall particularly during peroperative examination, should be recognized by pathologists.</description><identifier>ISSN: 0242-6498</identifier><identifier>PMID: 16230949</identifier><language>fre</language><publisher>France</publisher><subject>Adult ; Breast Neoplasms - pathology ; Diagnosis, Differential ; Female ; Humans ; Inflammation ; Lymphocytes - pathology ; Mastitis - pathology ; Mastitis - surgery ; Necrosis</subject><ispartof>Annales de pathologie, 2005-06, Vol.25 (3), p.231</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16230949$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Giusiano, Sophie</creatorcontrib><creatorcontrib>Andrac-Meyer, Lucile</creatorcontrib><creatorcontrib>Meunier-Carpentier, Séverine</creatorcontrib><creatorcontrib>Xerri, Luc</creatorcontrib><creatorcontrib>Boubli, L</creatorcontrib><creatorcontrib>Taranger-Charpin, Colette</creatorcontrib><title>A tumor-like lymphocytis mastitis</title><title>Annales de pathologie</title><addtitle>Ann Pathol</addtitle><description>A 44-year-old woman presenting with an inflammatory and palpable firm breast lump underwent surgical excision. Intraoperative frozen section analysis showed an extensive lesion consisting of ducts with intraluminal "necrosis". In addition, a very dense stromal inflammation was observed around these ducts, suggesting an invasive ductal carcinoma with predominant intraductal proliferation. However, on paraffin sections, epithelial cells close to the lymphocytic infiltrate were rare, subatrophic, without any neoplastic feature. The density and architecture of the lymphocytic infiltrate mimicked a breast lymphoma. However, immunochemistry and molecular biology investigation favored the diagnosis of a tumor-like lymphocytic mastitis. Although extremely rare, this particular form of lymphocytic mastitis, a diagnostic pitfall particularly during peroperative examination, should be recognized by pathologists.</description><subject>Adult</subject><subject>Breast Neoplasms - pathology</subject><subject>Diagnosis, Differential</subject><subject>Female</subject><subject>Humans</subject><subject>Inflammation</subject><subject>Lymphocytes - pathology</subject><subject>Mastitis - pathology</subject><subject>Mastitis - surgery</subject><subject>Necrosis</subject><issn>0242-6498</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpjYeA0MDIx0jUzsbTgYOAqLs4yMDAwNjc0YWfgMDQzMjawNLHkZFB0VCgpzc0v0s3JzE5VyKnMLcjIT64sySxWyE0sLskEMngYWNMSc4pTeaE0N4Ocm2uIs4duQWlSbmpKfEFRZm5iUWU8zExjggoAHgUrOA</recordid><startdate>200506</startdate><enddate>200506</enddate><creator>Giusiano, Sophie</creator><creator>Andrac-Meyer, Lucile</creator><creator>Meunier-Carpentier, Séverine</creator><creator>Xerri, Luc</creator><creator>Boubli, L</creator><creator>Taranger-Charpin, Colette</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>200506</creationdate><title>A tumor-like lymphocytis mastitis</title><author>Giusiano, Sophie ; Andrac-Meyer, Lucile ; Meunier-Carpentier, Séverine ; Xerri, Luc ; Boubli, L ; Taranger-Charpin, Colette</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-pubmed_primary_162309493</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>fre</language><creationdate>2005</creationdate><topic>Adult</topic><topic>Breast Neoplasms - pathology</topic><topic>Diagnosis, Differential</topic><topic>Female</topic><topic>Humans</topic><topic>Inflammation</topic><topic>Lymphocytes - pathology</topic><topic>Mastitis - pathology</topic><topic>Mastitis - surgery</topic><topic>Necrosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Giusiano, Sophie</creatorcontrib><creatorcontrib>Andrac-Meyer, Lucile</creatorcontrib><creatorcontrib>Meunier-Carpentier, Séverine</creatorcontrib><creatorcontrib>Xerri, Luc</creatorcontrib><creatorcontrib>Boubli, L</creatorcontrib><creatorcontrib>Taranger-Charpin, Colette</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Annales de pathologie</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Giusiano, Sophie</au><au>Andrac-Meyer, Lucile</au><au>Meunier-Carpentier, Séverine</au><au>Xerri, Luc</au><au>Boubli, L</au><au>Taranger-Charpin, Colette</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A tumor-like lymphocytis mastitis</atitle><jtitle>Annales de pathologie</jtitle><addtitle>Ann Pathol</addtitle><date>2005-06</date><risdate>2005</risdate><volume>25</volume><issue>3</issue><spage>231</spage><pages>231-</pages><issn>0242-6498</issn><abstract>A 44-year-old woman presenting with an inflammatory and palpable firm breast lump underwent surgical excision. Intraoperative frozen section analysis showed an extensive lesion consisting of ducts with intraluminal "necrosis". In addition, a very dense stromal inflammation was observed around these ducts, suggesting an invasive ductal carcinoma with predominant intraductal proliferation. However, on paraffin sections, epithelial cells close to the lymphocytic infiltrate were rare, subatrophic, without any neoplastic feature. The density and architecture of the lymphocytic infiltrate mimicked a breast lymphoma. However, immunochemistry and molecular biology investigation favored the diagnosis of a tumor-like lymphocytic mastitis. Although extremely rare, this particular form of lymphocytic mastitis, a diagnostic pitfall particularly during peroperative examination, should be recognized by pathologists.</abstract><cop>France</cop><pmid>16230949</pmid></addata></record> |
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source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
subjects | Adult Breast Neoplasms - pathology Diagnosis, Differential Female Humans Inflammation Lymphocytes - pathology Mastitis - pathology Mastitis - surgery Necrosis |
title | A tumor-like lymphocytis mastitis |
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