Intranasal immunisation with a 62 kDa proteinase combined with cholera toxin or CpG adjuvant protects against Trichomonas vaginalis genital tract infections in mice

Trichomonosis, caused by the protozoan parasite Trichomonas vaginalis, is one of the most frequent sexually transmitted diseases and is widely spread in all continents. Trichomonas vaginalis as well as other protozoan organisms have high levels of proteolitic activity mainly of the cysteine–proteina...

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Veröffentlicht in:	International journal for parasitology 2005-11, Vol.35 (13), p.1333-1337
Hauptverfasser:	Hernández, Hilda M., Figueredo, Mabel, Garrido, Nidia, Sánchez, Lizet, Sarracent, Jorge
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvant Adjuvants, Immunologic Administration, Intranasal Animals Antibodies, Protozoan - biosynthesis Antigens, Protozoan - immunology Biological and medical sciences Cholera Toxin - immunology Female Fundamental and applied biological sciences. Psychology Immunization - methods Immunoglobulin A - biosynthesis Immunoglobulin G - biosynthesis Life cycle. Host-agent relationship. Pathogenesis Mice Mice, Inbred BALB C Oligodeoxyribonucleotides - immunology Peptide Hydrolases - immunology Protection Proteinase Protozoa Protozoan Vaccines - immunology Trichomonas vaginalis Trichomonas vaginalis - immunology Trichomonas Vaginitis - immunology Trichomonas Vaginitis - prevention & control Vagina - immunology
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