Testing Differential Gene Expression in Functional Groups Goeman’s Global Test versus an ANCOVA Approach

Objectives: Single genes are not, in general, the primary focus of gene expression experiments. The researcher might be more interested in relevant pathways, functional sets, or genomic regions consisting of several genes. Efficient statistical tools to handle this task are of interest to research o...

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Veröffentlicht in:	Methods of information in medicine 2005, Vol.44 (3), p.449-453
Hauptverfasser:	Mansmann, U, Meister, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Analysis of Variance ANCOVA Biomarkers, Tumor Gene Expression Profiling - methods Gene Expression Profiling - standards Genetic Research global test Mathematical Computing Microarrays Oligonucleotide Array Sequence Analysis - methods Oligonucleotide Array Sequence Analysis - standards permutation test Signal Transduction - genetics
Online-Zugang:	Volltext
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