Rapidly developing optic neuritis secondary to ethambutol: possible mechanism of injury
Optic neuritis has been described among the toxic effects of Ethambutol. This side effect is dose related. The mean duration of Ethambutol induced optic neuritis (EON) is three months. We report a case of EON after few days of exposure to Ethambutol and the symptoms resolved after discontinuation of...
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Veröffentlicht in: | Journal of the Pakistan Medical Association 2005-07, Vol.55 (7), p.300 |
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description | Optic neuritis has been described among the toxic effects of Ethambutol. This side effect is dose related. The mean duration of Ethambutol induced optic neuritis (EON) is three months. We report a case of EON after few days of exposure to Ethambutol and the symptoms resolved after discontinuation of Ethambutol. This most likely represents an idiosyncratic reaction which is different as compared to dose related optic neuritis. |
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This side effect is dose related. The mean duration of Ethambutol induced optic neuritis (EON) is three months. We report a case of EON after few days of exposure to Ethambutol and the symptoms resolved after discontinuation of Ethambutol. This most likely represents an idiosyncratic reaction which is different as compared to dose related optic neuritis.</description><identifier>ISSN: 0030-9982</identifier><identifier>PMID: 16108516</identifier><language>eng</language><publisher>Pakistan</publisher><subject>Adult ; Antitubercular Agents - adverse effects ; Disease Progression ; Ethambutol - adverse effects ; Female ; Humans ; Optic Neuritis - chemically induced ; Optic Neuritis - diagnosis ; Time Factors</subject><ispartof>Journal of the Pakistan Medical Association, 2005-07, Vol.55 (7), p.300</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16108516$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ali, Sajjad</creatorcontrib><creatorcontrib>Usman, Uzma</creatorcontrib><creatorcontrib>Wasay, Mohammad</creatorcontrib><title>Rapidly developing optic neuritis secondary to ethambutol: possible mechanism of injury</title><title>Journal of the Pakistan Medical Association</title><addtitle>J Pak Med Assoc</addtitle><description>Optic neuritis has been described among the toxic effects of Ethambutol. This side effect is dose related. The mean duration of Ethambutol induced optic neuritis (EON) is three months. We report a case of EON after few days of exposure to Ethambutol and the symptoms resolved after discontinuation of Ethambutol. This most likely represents an idiosyncratic reaction which is different as compared to dose related optic neuritis.</description><subject>Adult</subject><subject>Antitubercular Agents - adverse effects</subject><subject>Disease Progression</subject><subject>Ethambutol - adverse effects</subject><subject>Female</subject><subject>Humans</subject><subject>Optic Neuritis - chemically induced</subject><subject>Optic Neuritis - diagnosis</subject><subject>Time Factors</subject><issn>0030-9982</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1j8tKAzEUQLNQ2lr7C5IfGLhJJpkZd1J8QUGQgsuSp02ZPJhkhPl7BXV1dodzrtAGgEEzDD1do5tSLgBUcIAVWhNBoOdEbNDHu8zejAs29suOKfv4iVOuXuNo58lXX3CxOkUjpwXXhG09y6DmmsZ7nFMpXo0WB6vPMvoScHLYx8s8Lbfo2smx2N0ft-j49HjcvzSHt-fX_cOhyYS2tXFKEOI6KYeWE2e6jg3OdZxLRiXAIBhRnDoNraaOd0oCJ5TrVmhqqOo526K7X22eVbDmlCcffkpP_4PsG27cTP8</recordid><startdate>200507</startdate><enddate>200507</enddate><creator>Ali, Sajjad</creator><creator>Usman, Uzma</creator><creator>Wasay, Mohammad</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>200507</creationdate><title>Rapidly developing optic neuritis secondary to ethambutol: possible mechanism of injury</title><author>Ali, Sajjad ; Usman, Uzma ; Wasay, Mohammad</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p124t-fb611f7aa9451fd7739ff755a32a009631b52fc04c2f57ba05125c46c2d2b853</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Adult</topic><topic>Antitubercular Agents - adverse effects</topic><topic>Disease Progression</topic><topic>Ethambutol - adverse effects</topic><topic>Female</topic><topic>Humans</topic><topic>Optic Neuritis - chemically induced</topic><topic>Optic Neuritis - diagnosis</topic><topic>Time Factors</topic><toplevel>online_resources</toplevel><creatorcontrib>Ali, Sajjad</creatorcontrib><creatorcontrib>Usman, Uzma</creatorcontrib><creatorcontrib>Wasay, Mohammad</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Journal of the Pakistan Medical Association</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ali, Sajjad</au><au>Usman, Uzma</au><au>Wasay, Mohammad</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Rapidly developing optic neuritis secondary to ethambutol: possible mechanism of injury</atitle><jtitle>Journal of the Pakistan Medical Association</jtitle><addtitle>J Pak Med Assoc</addtitle><date>2005-07</date><risdate>2005</risdate><volume>55</volume><issue>7</issue><spage>300</spage><pages>300-</pages><issn>0030-9982</issn><abstract>Optic neuritis has been described among the toxic effects of Ethambutol. This side effect is dose related. The mean duration of Ethambutol induced optic neuritis (EON) is three months. We report a case of EON after few days of exposure to Ethambutol and the symptoms resolved after discontinuation of Ethambutol. This most likely represents an idiosyncratic reaction which is different as compared to dose related optic neuritis.</abstract><cop>Pakistan</cop><pmid>16108516</pmid></addata></record> |
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source | MEDLINE; Directory of Open Access Journals; EZB Electronic Journals Library |
subjects | Adult Antitubercular Agents - adverse effects Disease Progression Ethambutol - adverse effects Female Humans Optic Neuritis - chemically induced Optic Neuritis - diagnosis Time Factors |
title | Rapidly developing optic neuritis secondary to ethambutol: possible mechanism of injury |
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