EFFECT OF AN ACUTE DOSE OF ALCOHOL ON THE PHARMACOKINETICS OF ORAL NIFEDIPINE IN HUMANS

Pharmacokinetic and pharmacodynamic interactions of alcohol and nifedipine were assessed in 10 healthy human volunteers. Doses of 20 mg (2 x 10-mg capsules) of nifedipine were administered with either 150 ml of orange juice or 75 ml of alcohol (94%) in 75 ml of orange juice according to a crossover...

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