In vivo pressure estimation using subharmonic contrast microbubble signals: proof of concept

Changes in ambient pressure affects the reflectivity of ultrasound contrast microbubbles leading to an excellent correlation between subharmonic signals and hydrostatic pressure. The aortas of two dogs were scanned with an experiment pulse-echo system to validate in vivo pressure estimation based on...

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Veröffentlicht in:	IEEE transactions on ultrasonics, ferroelectrics, and frequency control ferroelectrics, and frequency control, 2005-04, Vol.52 (4), p.581-583
Hauptverfasser:	Forsberg, F., Ji-Bin Liu, Shi, W.T., Furuse, J., Shimizu, M., Goldberg, B.B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acoustics Algorithms Animals Aorta Aorta - diagnostic imaging Aorta - physiology Bandwidth Biocompatibility Biological and medical sciences Biomedical materials Blood Pressure Determination - methods Cardiovascular system Contrast Media Dogs Echocardiography - methods Exact sciences and technology Feasibility Studies Ferric Compounds Frequency estimation Fundamental areas of phenomenology (including applications) General equipment and techniques Image Enhancement - methods Image Interpretation, Computer-Assisted - methods In vivo In vivo testing In vivo tests Instruments, apparatus, components and techniques common to several branches of physics and astronomy Investigative techniques, diagnostic techniques (general aspects) Iron Medical sciences Microbubbles Microorganisms Oxides Physics Pressure measurement Pulse amplifiers Pulse generation Reproducibility of Results Scattering Sensitivity and Specificity Shape Surgical implants Transducers Ultrasonic imaging Ultrasonic investigative techniques Ultrasonics, quantum acoustics, and physical effects of sound
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Zusammenfassung:	Changes in ambient pressure affects the reflectivity of ultrasound contrast microbubbles leading to an excellent correlation between subharmonic signals and hydrostatic pressure. The aortas of two dogs were scanned with an experiment pulse-echo system to validate in vivo pressure estimation based on subharmonic microbubble signals. Results matched well with instantaneous pressure measurements (from 20-60 mmHg) obtained simultaneously with a pressure catheter (root mean square errors
ISSN:	0885-3010 1525-8955
DOI:	10.1109/TUFFC.2005.1428040