Adaptive responses to mitochondrial dysfunction in the rho degrees Namalwa cell

Mitochondrial function depends on the synchronised expression of nuclear and mitochondrial-encoded genes. The expression of many nuclear genes is sensitive to the functional state of mitochondria. Mitochondria containing mutated mtDNA populations have been shown to withstand stress to a high level o...

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Veröffentlicht in:	Mitochondrion 2005-06, Vol.5 (3), p.173
Hauptverfasser:	Behan, Aine, Doyle, Sineaid, Farrell, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation, Physiological Adenosine Triphosphatases - analysis Adenosine Triphosphatases - metabolism Cell Culture Techniques Cell Hypoxia - drug effects Cell Line, Tumor Cobalt - toxicity DNA, Mitochondrial - drug effects DNA, Mitochondrial - genetics DNA-Binding Proteins - analysis DNA-Binding Proteins - genetics Ethidium - pharmacology Gene Expression Regulation, Neoplastic Humans Hypoxia-Inducible Factor 1 Hypoxia-Inducible Factor 1, alpha Subunit Kinetics Mitochondria - genetics Mitochondria - metabolism Mitochondrial Proteins - analysis Mitochondrial Proteins - genetics Mitochondrial Proteins - metabolism Nuclear Proteins - analysis Nuclear Proteins - genetics Oligonucleotide Array Sequence Analysis Oxidative Phosphorylation Polymerase Chain Reaction Transcription Factors - analysis Transcription Factors - genetics Transcription, Genetic
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