The neuroprotective KDI domain of gamma 1-laminin is a universal and potent inhibitor of ionotropic glutamate receptors

Previous work from this laboratory indicates that the KDI (Lys-Asp-Ile) domain of gamma 1-laminin promotes functional regeneration of adult rat spinal cord injuries and protects adult rat hippocampal neurons against massive neuronal death induced by intracerebral injection of the glutamate analogue...

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Veröffentlicht in:	Journal of neuroscience research 2005-09, Vol.81 (6), p.797
Hauptverfasser:	Möykkynen, Tommi, Liebkind, Ron, Sjöberg, Jari, Korpi, Esa R, Liesi, Päivi
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line Cells, Cultured Electrophysiology Excitatory Amino Acid Antagonists Humans Immunohistochemistry Laminin - pharmacology Membrane Potentials - physiology Nerve Regeneration - drug effects Neurons - physiology Neuroprotective Agents - pharmacology Patch-Clamp Techniques Receptors, AMPA - drug effects Receptors, Glutamate - drug effects Receptors, N-Methyl-D-Aspartate - drug effects
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