$Biweekly Docetaxel-Irinotecan Treatment with Filgrastim Support Is Highly Active in Antracycline-Paclitaxel-Refractory Breast Cancer Patients$

Biweekly Docetaxel-Irinotecan Treatment with Filgrastim Support Is Highly Active in Antracycline-Paclitaxel-Refractory Breast Cancer Patients

Purpose: To evaluate the feasibility and activity of combination treatment with docetaxel (DTX) and irinotecan (CPT-11), given together every other week, combined with filgrastim support, in anthracycline- and paclitaxel-pretreated breast cancer (BC) patients. Patients and Methods: Advanced BC patie...

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Veröffentlicht in:	Oncology 2005-01, Vol.68 (4-6), p.391-397
Hauptverfasser:	Frasci, Giuseppe, D’Aiuto, Giuseppe, Thomas, Renato, Comella, Pasquale, Di Bonito, Maurizio, Lapenta, Liliana, D’Aiuto, Massimiliano, Botti, Gerardo, Vallone, Paolo, De Rosa, Vincenzo, D’Aniello, Roberta, Giordano, Renato, Comella, Giuseppe
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Anthracyclines - administration & dosage Antineoplastic Combined Chemotherapy Protocols - therapeutic use Breast cancer Breast Neoplasms - drug therapy Breast Neoplasms - secondary Camptothecin - administration & dosage Camptothecin - analogs & derivatives Chemotherapy Clinical Study Clinical trials Disease-Free Survival Dose-Response Relationship, Drug Feasibility Studies Female Filgrastim Granulocyte Colony-Stimulating Factor - administration & dosage Humans Maximum Tolerated Dose Middle Aged Neoplasm Staging Paclitaxel - administration & dosage Recombinant Proteins Salvage Therapy Taxoids - administration & dosage
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