Atopic dermatitis - topical therapy: Do patients apply much too little?
Background: The treatment of atopic dermatitis still remains a challenge. Little research has been done on the issue of the extent to which patients correctly use prescribed topical preparations under everyday conditions. Aims: To investigate what quantity of topical preparations is applied by outpa...
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| Veröffentlicht in: | The Journal of dermatological treatment 2005-04, Vol.16 (2), p.95-101 |
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| creator | Niemeier, V. Kupfer, J. Schill, W. -B. Gieler, U. |
| description | Background: The treatment of atopic dermatitis still remains a challenge. Little research has been done on the issue of the extent to which patients correctly use prescribed topical preparations under everyday conditions. Aims: To investigate what quantity of topical preparations is applied by outpatients in daily routine treatment over a 26-week period and to what extent this consumption is related to the course of the severity of patients' skin conditions. Methods: Thirty adult outpatients (20 female and 10 male) with atopic dermatitis were examined at four different times during 26 weeks. For treatment and skin care these patients were given a topical glucocorticoid preparation (prednicarbate) and the corresponding emollient. Results: The average severity rating (SCORAD) was 29.6 (before therapy 33.9, after 26 weeks 27.4). The SCORAD indices improved by a mean of 6.5 points (p |
| doi_str_mv | 10.1080/09546630510027895 |
| format | Article |
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Little research has been done on the issue of the extent to which patients correctly use prescribed topical preparations under everyday conditions. Aims: To investigate what quantity of topical preparations is applied by outpatients in daily routine treatment over a 26-week period and to what extent this consumption is related to the course of the severity of patients' skin conditions. Methods: Thirty adult outpatients (20 female and 10 male) with atopic dermatitis were examined at four different times during 26 weeks. For treatment and skin care these patients were given a topical glucocorticoid preparation (prednicarbate) and the corresponding emollient. Results: The average severity rating (SCORAD) was 29.6 (before therapy 33.9, after 26 weeks 27.4). The SCORAD indices improved by a mean of 6.5 points (p<0.05). Conclusion: Patients who applied the correct amount of the prednicarbate-containing preparations (not less than 90% of 0.5 g dm2) to the areas of affected skin showed a significant improvement in SCORAD indices across the four measuring times.</description><identifier>ISSN: 0954-6634</identifier><identifier>EISSN: 1471-1753</identifier><identifier>DOI: 10.1080/09546630510027895</identifier><identifier>PMID: 16019623</identifier><language>eng</language><publisher>Oslo: Informa UK Ltd</publisher><subject>Administration, Topical ; Adult ; Adults ; Biological and medical sciences ; compliance ; Dermatitis, Atopic - drug therapy ; emollients ; Emollients - administration & dosage ; Female ; glucocorticoids ; Glucocorticoids - administration & dosage ; Humans ; Male ; Medical sciences ; Pharmacology. Drug treatments ; Prednisolone - administration & dosage ; Prednisolone - analogs & derivatives ; Self Administration ; Severity of Illness Index ; skin disease ; Skin, nail, hair, dermoskeleton ; Time Factors</subject><ispartof>The Journal of dermatological treatment, 2005-04, Vol.16 (2), p.95-101</ispartof><rights>2005 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 2005</rights><rights>2005 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c500t-c14402301085d2e3baa46e845d22806ee0bb845c67b6efec97398f4cf1d817823</citedby><cites>FETCH-LOGICAL-c500t-c14402301085d2e3baa46e845d22806ee0bb845c67b6efec97398f4cf1d817823</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.1080/09546630510027895$$EPDF$$P50$$Ginformaworld$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.1080/09546630510027895$$EHTML$$P50$$Ginformaworld$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,59647,60436,61221,61402</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16737013$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16019623$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Niemeier, V.</creatorcontrib><creatorcontrib>Kupfer, J.</creatorcontrib><creatorcontrib>Schill, W. -B.</creatorcontrib><creatorcontrib>Gieler, U.</creatorcontrib><title>Atopic dermatitis - topical therapy: Do patients apply much too little?</title><title>The Journal of dermatological treatment</title><addtitle>J Dermatolog Treat</addtitle><description>Background: The treatment of atopic dermatitis still remains a challenge. Little research has been done on the issue of the extent to which patients correctly use prescribed topical preparations under everyday conditions. Aims: To investigate what quantity of topical preparations is applied by outpatients in daily routine treatment over a 26-week period and to what extent this consumption is related to the course of the severity of patients' skin conditions. Methods: Thirty adult outpatients (20 female and 10 male) with atopic dermatitis were examined at four different times during 26 weeks. For treatment and skin care these patients were given a topical glucocorticoid preparation (prednicarbate) and the corresponding emollient. Results: The average severity rating (SCORAD) was 29.6 (before therapy 33.9, after 26 weeks 27.4). The SCORAD indices improved by a mean of 6.5 points (p<0.05). Conclusion: Patients who applied the correct amount of the prednicarbate-containing preparations (not less than 90% of 0.5 g dm2) to the areas of affected skin showed a significant improvement in SCORAD indices across the four measuring times.</description><subject>Administration, Topical</subject><subject>Adult</subject><subject>Adults</subject><subject>Biological and medical sciences</subject><subject>compliance</subject><subject>Dermatitis, Atopic - drug therapy</subject><subject>emollients</subject><subject>Emollients - administration & dosage</subject><subject>Female</subject><subject>glucocorticoids</subject><subject>Glucocorticoids - administration & dosage</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Pharmacology. Drug treatments</subject><subject>Prednisolone - administration & dosage</subject><subject>Prednisolone - analogs & derivatives</subject><subject>Self Administration</subject><subject>Severity of Illness Index</subject><subject>skin disease</subject><subject>Skin, nail, hair, dermoskeleton</subject><subject>Time Factors</subject><issn>0954-6634</issn><issn>1471-1753</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMFO3DAQhi0E6i7bPgCXyhe4BcZx4jgtEkJAFySkXtpz5DgTbZATp7YjlLfHyy6iVSVO1ni-fzTzEXLC4JyBhAso80wIDjkDSAtZ5gdkybKCJazI-SFZbvtJBLIFOfb-CYBxAfITWTABrBQpX5L1dbBjp2mDrlehC52nCX39UoaGDTo1zt_oraVj7OIQPFXjaGbaT3oTOUtNF4LBq8_kqFXG45f9uyK_f9z9urlPHn-uH26uHxOdA4REsyyDlENcP29S5LVSmUCZxSKVIBChrmOlRVELbFGXBS9lm-mWNZIVMuUrcrabOzr7Z0Ifqr7zGo1RA9rJV0IC59vTVoTtQO2s9w7banRdr9xcMai29qr_7MXM1_3wqe6xeU_sdUXgdA8oHwW1Tg26839xBS-i5Mhd7rhuaG0U-2ydaaqgZmPdW4h_tMf3f-IbVCZstHJYPdnJDVHwB1e8ACMqmvY</recordid><startdate>20050401</startdate><enddate>20050401</enddate><creator>Niemeier, V.</creator><creator>Kupfer, J.</creator><creator>Schill, W. -B.</creator><creator>Gieler, U.</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20050401</creationdate><title>Atopic dermatitis - topical therapy: Do patients apply much too little?</title><author>Niemeier, V. ; Kupfer, J. ; Schill, W. -B. ; Gieler, U.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c500t-c14402301085d2e3baa46e845d22806ee0bb845c67b6efec97398f4cf1d817823</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Administration, Topical</topic><topic>Adult</topic><topic>Adults</topic><topic>Biological and medical sciences</topic><topic>compliance</topic><topic>Dermatitis, Atopic - drug therapy</topic><topic>emollients</topic><topic>Emollients - administration & dosage</topic><topic>Female</topic><topic>glucocorticoids</topic><topic>Glucocorticoids - administration & dosage</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Pharmacology. Drug treatments</topic><topic>Prednisolone - administration & dosage</topic><topic>Prednisolone - analogs & derivatives</topic><topic>Self Administration</topic><topic>Severity of Illness Index</topic><topic>skin disease</topic><topic>Skin, nail, hair, dermoskeleton</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Niemeier, V.</creatorcontrib><creatorcontrib>Kupfer, J.</creatorcontrib><creatorcontrib>Schill, W. -B.</creatorcontrib><creatorcontrib>Gieler, U.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of dermatological treatment</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Niemeier, V.</au><au>Kupfer, J.</au><au>Schill, W. -B.</au><au>Gieler, U.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Atopic dermatitis - topical therapy: Do patients apply much too little?</atitle><jtitle>The Journal of dermatological treatment</jtitle><addtitle>J Dermatolog Treat</addtitle><date>2005-04-01</date><risdate>2005</risdate><volume>16</volume><issue>2</issue><spage>95</spage><epage>101</epage><pages>95-101</pages><issn>0954-6634</issn><eissn>1471-1753</eissn><abstract>Background: The treatment of atopic dermatitis still remains a challenge. Little research has been done on the issue of the extent to which patients correctly use prescribed topical preparations under everyday conditions. Aims: To investigate what quantity of topical preparations is applied by outpatients in daily routine treatment over a 26-week period and to what extent this consumption is related to the course of the severity of patients' skin conditions. Methods: Thirty adult outpatients (20 female and 10 male) with atopic dermatitis were examined at four different times during 26 weeks. For treatment and skin care these patients were given a topical glucocorticoid preparation (prednicarbate) and the corresponding emollient. Results: The average severity rating (SCORAD) was 29.6 (before therapy 33.9, after 26 weeks 27.4). The SCORAD indices improved by a mean of 6.5 points (p<0.05). Conclusion: Patients who applied the correct amount of the prednicarbate-containing preparations (not less than 90% of 0.5 g dm2) to the areas of affected skin showed a significant improvement in SCORAD indices across the four measuring times.</abstract><cop>Oslo</cop><pub>Informa UK Ltd</pub><pmid>16019623</pmid><doi>10.1080/09546630510027895</doi><tpages>7</tpages></addata></record> |
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| subjects | Administration, Topical Adult Adults Biological and medical sciences compliance Dermatitis, Atopic - drug therapy emollients Emollients - administration & dosage Female glucocorticoids Glucocorticoids - administration & dosage Humans Male Medical sciences Pharmacology. Drug treatments Prednisolone - administration & dosage Prednisolone - analogs & derivatives Self Administration Severity of Illness Index skin disease Skin, nail, hair, dermoskeleton Time Factors |
| title | Atopic dermatitis - topical therapy: Do patients apply much too little? |
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